Taheri Ahmad Reza; Sherafati Golrokh; Sadrneshin Mohsen; Poorzand Hoorak; Kiafar Bita
Volume 18, Issue 4 , 2015, , Pages 187-188
Abstract
Recent studies suggest that psoriasis may be an independent risk factor for the development of cardiovascular diseases. Myocardial infarction, pulmonary embolism, diabetes mellitus,hypertension, and dyslipidemia have been reported in patients with psoriasis Certain risk factors for cardiovascular diseases ...
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Recent studies suggest that psoriasis may be an independent risk factor for the development of cardiovascular diseases. Myocardial infarction, pulmonary embolism, diabetes mellitus,hypertension, and dyslipidemia have been reported in patients with psoriasis Certain risk factors for cardiovascular diseases may be more prevalent among patients with psoriasis 3,4. The aim of this study was to define the risk factors of cardiovascular diseases in patients with psoriasis in Iran . Twentyfive patients (13 female and 12 male) over 18 years old with active plaque psoriasis regardless of its severity who were treated with psoralenultraviolet A (PUVA) in Imam Reza Dermatology Clinic were enrolled in this study. After obtainingmedical history taking and performing full physical examination, blood pressure, weight, and height of thee particinpants were measured. Then, their body mass index (BMI) was calculated and recorded. The control group consisted of 25 healthy individuals who were age and sex matched. The patients who were pregnant, and those with a history of anysystemic disease or under systemic medications were excluded from the study.
Taheri Ahmad Reza; Farmanbar Mohammad Ali; Kiafar Bita; Khajedaluee Mohammad; Javidi Zari; Nahidi Yalda; Maleki Masoud
Volume 17, Issue 1 , 2014, , Pages 1-7
Abstract
Background: The standard patch test is known as the most reliable test to identify and confirm causative agents of allergic contact dermatitis (ACD). Previous studies have shown that the prevalence of specific allergens varies by geographic area. The results of patch test in patients visiting our dermatology ...
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Background: The standard patch test is known as the most reliable test to identify and confirm causative agents of allergic contact dermatitis (ACD). Previous studies have shown that the prevalence of specific allergens varies by geographic area. The results of patch test in patients visiting our dermatology clinics with suspected ACD were prospectively investigated and compared with those reported in the literature of Iran.Method: We performed the European Standard Series patch test produced by Almiral Hermal GmbH, containing 28 allergens in a group of 100 patients (55 females and 45 males) with suspected ACD who were referred to Emam Reza and Ghaem Hospitals, Mashhad, in 2010-2011. The tests were read after 2 and 4 days.Result: Fifty-four percent of the patients had 1 or more positive reactions of which 65% were relevant to current or past dermatitis. Positive reactions were due to 12 allergens. The most frequent allergens were nickel sulfate (25%) and potassium
Shahzad Shahid; Taheri Ahmad Reza; Javidi Zari; Dorgalaleh Akbar; Tabibian Shadi; Bamedi Taregh; Dorgalaleh Saeed; Moemeni Mohammad
Volume 17, Issue 1 , 2014, , Pages 22-26
Abstract
Background: Vitiligo is a common acquired disorder of the skin. The disease is characterized by depigmented macules and patches on the skin. Autoimmunity has a crucial role in the pathogenesis of the vitiligo. Vitiligo is frequently associated with different autoimmune diseases such as thyroid abnormalities ...
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Background: Vitiligo is a common acquired disorder of the skin. The disease is characterized by depigmented macules and patches on the skin. Autoimmunity has a crucial role in the pathogenesis of the vitiligo. Vitiligo is frequently associated with different autoimmune diseases such as thyroid abnormalities and diabetes. This study aimed to evaluate the association between vitiligo and diabetes mellitus.Method: This case-control study was conducted on 70 patients with established vitiligo disorder and 70 non vitiligo individuals as the control group. In the case group, we performed two tests, fasting blood sugar (FBS) and oral glucose oral tolerance test (OGTT), while only FBS was checked in the control group.Result: The results of our study showed that out of 70 people in the case group, 18 (25.71%) had impaired FBS while only 4 (5.7%) had impaired GTT3. Statistical analysis showed p-value=0.015 which indicated a significant difference in impaired FBS between case and control groups. We had half and 1 hour GTT data (GTT1 and GTT2) and all patients with impaired GTT1 (4 individuals) and GTT2 (5 individuals) were females with a significant difference (P-value = 0.021 and 0.017, respectively).Conclusion: Periodical laboratory investigation for diabetes mellitus in vitiligo patients, particularly in females, seems to be necessary.
Mashayekhi Vahid; Mahmoudi Mahmoud; Rastin Maryam; Tayebi Naser; Taheri Ahmad Reza; Tavakoli Maryam
Volume 15, Issue 3 , 2012, , Pages 69-73
Abstract
Background: Chronic lupoid leishmaniasis (CLL) is a chronicform of cutaneous leishmaniasis that is usually resistant to antileishmania agents and leishmania is not seen in the histologicsections. We used polymerase chain reaction (PCR) to detectleishmania DNA in CLL specimens.Method: This descriptive ...
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Background: Chronic lupoid leishmaniasis (CLL) is a chronicform of cutaneous leishmaniasis that is usually resistant to antileishmania agents and leishmania is not seen in the histologicsections. We used polymerase chain reaction (PCR) to detectleishmania DNA in CLL specimens.Method: This descriptive cross sectional study was done on20 paraffin embedded specimens of CLL cases referred to thedermatology clinic of Imam Reza Hospital, Mashhad, Iran.Patients’ information including age, sex, duration and location ofthe lesion was obtained and then skin specimens were reviewedhistopathologically and assessed for leishmania DNA using PCR.Result: Eleven male and 9 female patients with a mean age of17.95 years were included in our study. The
Meibodi Naser Tayyebi; Nahidi Yalda; Javidi Zari; Taheri Ahmad Reza; Jahanfakhr Monavar Afzalaghaee Samaneh
Volume 15, Issue 3 , 2012, , Pages 89-94
Abstract
Background: Precancerous lesions are disorders that are highlylikely to become malignant. Early diagnosis of precancerous skinlesions helps to prevent skin cancers. The aim of this study wasclinicopathological assessment of precancerous skin lesions inpatients referred to the dermatology department of ...
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Background: Precancerous lesions are disorders that are highlylikely to become malignant. Early diagnosis of precancerous skinlesions helps to prevent skin cancers. The aim of this study wasclinicopathological assessment of precancerous skin lesions inpatients referred to the dermatology department of Imam Rezahospital.Method: Two hundred and nine patients who were diagnosed withprecancerous lesions and referred to the dermatology departmentof Imam Reza hospital from 1997 to 2007 were studied. Studyparameters included participants’ age, sex and occupation, typeof precancerous skin lesion, clinicopathological type of the lesionand location. The data was collected from the patients’ recordsin the dermatology department and their microscopic slides inthe pathology department.Result: The most common precancerous skin lesion was actinickeratosis (68.4%) followed by Bowen’s disease (7.2%). About67.5% of the patients were male with a mean age of 61.7 years.Moreover, 53.1% of the patients worked outdoors. The mostcommon site of the lesions was head and neck (83.3%) and 18.7%of lesions were associated with malignancy. The most commonpathological form of actinic keratosis was the proliferative type(28.9%).Conclusion: The results of this study showed that precancerousskin lesions were more prevalent in men aged over 50 years, insun-exposed areas and in occupations practiced outdoors. Inaddition to squamous cell carcinoma, these lesions could alsobe associated with basal cell carcinoma.
Mashayekhi Vahid; Maleki Masoud; Javidi Zari; Mahmodi Mahmoud; Taheri Ahmad Reza; Mehrabi Reza
Volume 11, Issue 2 , 2008, , Pages 60-63
Abstract
Background: It appears that chronic lupoid leishmaniasis is the result of type 2 predominant T helper response to parasite and a defect in the down regulation of IL-4 production during infection. The objective of this study was to evaluate the underlying immune status in these patients and their predominant ...
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Background: It appears that chronic lupoid leishmaniasis is the result of type 2 predominant T helper response to parasite and a defect in the down regulation of IL-4 production during infection. The objective of this study was to evaluate the underlying immune status in these patients and their predominant T helper activity we considered serum IgE as an indicator of TH2 activity and IL-4 production as it has been shown in atopic diathesis.Methods: In 34 cases of chronic lupoid leishmaniasis serum IgE level was measured and compared with 34 control cases of age and sex matched healthy individuals without atopic diathesis. P< 0.05 was considered statistically significant.Results: There were 21 females and 13 males with a mean age of 14.35±8.3 years in the patients group. The mean age of the control group was 16.11±8.4 (P>0.05 and matched). Nine patients had atopic diathesis. Mean serum IgE level in patients and in the control group was 102.6±22.4 i.u/ml and 135.6±24.9 i.u/ml, respectively (P>0.05 with no significant difference). Mean serum IgE level in patients without atopic diathesis (25 cases) was 66.8±11.3i.u/ml which was significantly lower than the control group (P<0.05).Conclusion: In this study, serum IgE level in cases with chronic lupoid leishmaniasis was lower than the control group and it seems that in these patients, there is not an underlying Th2 over activity as it is seen in atopic diathesis.
Javidi Zari; Tayyebi-Maybodie Naser; Taheri Ahmad Reza; Nahidi Yalda
Volume 10, Issue 4 , 2007, , Pages 309-315
Abstract
Background and aim: Psoriasis is a dermatologic disease which not only involves the patient physically, but also affects patient's quality of life. Due to its life time duration and psychologic burden, we decided to evaluate patient's quality of life using psoriasis disability index (PDI). Materials ...
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Background and aim: Psoriasis is a dermatologic disease which not only involves the patient physically, but also affects patient's quality of life. Due to its life time duration and psychologic burden, we decided to evaluate patient's quality of life using psoriasis disability index (PDI). Materials and methods: From August 2006 till March 2007, 80 patients referring to Imam-Reza dermatology clinic completed the PDI questionnaire and a demographic questionnaire. Collected data were analyzed by t-test, one way ANOVA tests using SPSS software. Results: 46.2% of patients were male and 53.8% female. The mean age of patients was 40.2 years. 10% had positive family history of psoriasis. 47.5% had a history of hospitalization. 41.3% had articular and 53.8% had nail involvement. Mean morbidity duration was 12.6 years and mean PDI score was 17.4±10 (maximum and minimum scores: 37 and 1 respectively). There was significant difference in mean PDI score in groups considering age, sex, education, location, duration and extent of disease, hospitalization history, nail involvement and type of treatment. Most disability was seen in the treatment field (both sexes) and occupation /school (men) and least disability was seen in individual relationships.Discussion: Psoriasis can reduce the patient's quality of life and satisfaction severely. Therefore supportive strategies can improve their quality of life.