Ehsani Amir Hooshang; Noormohammadpoor Pedram; Sadeghinia Ali; Hemmati Sara; Ahmadi Maedeh; Sotoudeh Sara; Azizpour Arghavan; Nasimi Maryam
Volume 20, Issue 4 , 2017, , Pages 118-121
Abstract
Background: Basal cell carcinoma (BCC), the most common form of skin cancer, usually occurs in the sun-exposed areas of the body like head and neck, yet is also seen in unexpected sites. Myriad studies have mentioned a lower limb BCC incidence rate of 1.5-13.5%.Methods: The present retrospective cross-sectional ...
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Background: Basal cell carcinoma (BCC), the most common form of skin cancer, usually occurs in the sun-exposed areas of the body like head and neck, yet is also seen in unexpected sites. Myriad studies have mentioned a lower limb BCC incidence rate of 1.5-13.5%.Methods: The present retrospective cross-sectional study was conducted on 650 BCC patients, who were referred to the dermatology tumor clinic of Razi hospital from 2008 to 2012 with confirmed biopsy results of BCC. Patient characteristics including age, sex, relevant history and physical examination and tumor characteristics such as location and pathological subtypes were recorded.Results: The prevalence of lower limb BCC was 1.53% with the mean age of 69.5 years and a male to female ratio of 2.33:1. Of 10 cases with BCC on the lower extremities, 6 were on the legs, 3 on the thighs and 1 on the foot. The most frequent pathological type was nodular and constant UV exposure was the most important risk factor (60%). Other underlying factors were chemical exposure, chronic ulcer and history of radiation.Conclusion: BCC of the lower limbs is more prevalent in men compared with women. Moreover, UV exposure is the most important risk factor for BCC. On the other hand, factors like ulcers, radiation and chemical exposure have to be further considered.
Seirafi Hassan; Fateh Soheil; Farnaghi Farshad; Ehsani Amir Hooshang; Noormohammadpoor Pedram
Volume 13, Issue 1 , 2010, , Pages 1-5
Abstract
Background: Although cryotherapy is still the first-line therapy for solar lentigines, due to side effects such as post-inflammatory hyperpigmentation (PIH), especially in patients with darker skin types, pigment specific lasers should be considered as initial treatment. The aim of this study was to ...
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Background: Although cryotherapy is still the first-line therapy for solar lentigines, due to side effects such as post-inflammatory hyperpigmentation (PIH), especially in patients with darker skin types, pigment specific lasers should be considered as initial treatment. The aim of this study was to evaluate the efficacy and safety of cryotherapy in comparison with 595-nm pulsed dye laser (PDL) with cutaneous compression in the treatment of solar lentigines. Method: Twenty two patients (skin type II- IV) with facial or hand lentigines completed this study. Lesions of one side of the face or each hand were randomly assigned and treated with either cryotherapy or PDL. Treatments were performed with radiant exposures of 10 J/cm2, 7mm spot size and 1.5ms pulse duration with no epidermal cooling. Photographs were taken before treatment and one month later. The response rate and side effects were compared. Results: PDL was more likely to produce substantial lightening of solar lentigines than cryotherapy, especially in skin types III and IV (n=8, n=9; P0.05). PIH was only seen in the cryotherapy group. PDL group only showed minimal erythema. No purpura was observed. Conclusion: PDL with compression is superior to cryotherapy in the treatment of solar lentigines in darker skin types.
Ehsani Amir Hooshang; Toosi Siavash; Noormohamadpour Pedram; Hosseini Mahboubeh; Nazeman Leila
Volume 11, Issue 4 , 2008, , Pages 143-146
Abstract
Background: Pityriasis rosea is an inflammatory skin disorder with a known response to erythromycin. Considering similarities between erythromycin and azithromycin and lesser adverse effects of the latter, in a pilot study, we gave azithromycin to seven patients with pityriasis rosea and observed a noticeable ...
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Background: Pityriasis rosea is an inflammatory skin disorder with a known response to erythromycin. Considering similarities between erythromycin and azithromycin and lesser adverse effects of the latter, in a pilot study, we gave azithromycin to seven patients with pityriasis rosea and observed a noticeable improvement. The aim of this study was to evaluate the efficacy of azithromycin in patients with pityriasis rosea.Methods: A double-blind, placebo-controlled clinical trial was performed in our clinic. Sixty patients over a period of 20 months were alternatively assigned to the treatment group or the placebo group. Patients in the treatment group received azithromycin, 250 mg/day, for 14 days. The response was categorized as complete response, partial response, or no response. All patients were followed up for 2 months.Results: Age at presentation, sex, and average duration of the disease were comparable in both groups. Complete response was observed in 19 patients (63.3 %) in the treatment group and two in the placebo group (p<0.0001).Conclusion: Oral azithromycin is effective in treating patients with pityriasis rosea.
Hosseini Mahboobeh-Sadat; Ehsani Amir Hooshang; Hosseinpanah Farhad; Azizi Fereydoon; Salami Maryam; Khedmat Hossein
Volume 11, Issue 3 , 2008, , Pages 113-117
Abstract
Bachground: Skin lesions are common in type 2 diabetic patients and its association with microvascular complications been reported. Methods: In this study, 1135 type-2 diabetic patients were included and examined by a dermatologist for diabetes mellitus related skin lesions, skin infections and cutaneous ...
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Bachground: Skin lesions are common in type 2 diabetic patients and its association with microvascular complications been reported. Methods: In this study, 1135 type-2 diabetic patients were included and examined by a dermatologist for diabetes mellitus related skin lesions, skin infections and cutaneous complications of the treatment. Smear, culture and biopsy of the lesions were done for definite diagnosis. Weight, height, blood pressure were also done. FBS and HbA1C were measured for all patients Results: The mean age of the study population was 54±11 years; 619 were (55%) female and 516 were (45%) male. Mean duration of the disease was 9±7 years and HbA1c was 7.8±1.6. The prevalence of skin lesions was 64% (95%CI: 61.2-66.8). The most common solitary skin lesion was diabetic dermopathy (32.3%) while the most common condition observed overall was skin infections (41.5%). Acanthosis nigricans with a prevalence of 26.4% was the third most common lesion. Other skin conditions had a prevalence of less than 12%. Skin disorders were apparently more prevalent in male than in female patients.Conclusion: More than sixty percent of patients with type-2 diabetes mellitus have skin lesions.