Pedram Noormohammadpour; Somayeh Khezri; Zahra Safaee Naraghi; Alireza Ghanadan; Farzaneh Khezri
Volume 15, Issue 4 , 2012, , Pages 134-136
Abstract
Confluent and Reticulate Papillomatosis (CRP) is a rare disease withpoorly recognized etiology. Various agents such as antibacterial,topical/systemic antifungal and topical/oral retinoids have beenused as treatment. Here, we report a 15-year-old female withCRP in whom yeasts of Malassezia were found ...
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Confluent and Reticulate Papillomatosis (CRP) is a rare disease withpoorly recognized etiology. Various agents such as antibacterial,topical/systemic antifungal and topical/oral retinoids have beenused as treatment. Here, we report a 15-year-old female withCRP in whom yeasts of Malassezia were found in the PAS stainof the skin lesions. Topical terbinafine hydrochloride 1% sprayand oral fluconazole disappeared the lesions, supporting thehypothesis that CRP maybe a reactive dermatosis to Malassezia..
Hassan Seirafi; Maryam Daneshpazhouh; Somayeh Khezri; Pardis Kiani; Sara Sabouri Rad; khadijeh Moghadam; Farzaneh Khezri
Volume 14, Issue 2 , 2011, , Pages 58-63
Abstract
Background: There is a large variety of therapeutic agents for the treatment of vitiligo, but it still remains a challenge. Narrow-band UVB phototherapy and 308-nm excimer laser have been shown to be safe and effective for the treatment of vitiligo. Topical calcipotriol has recently been reported to ...
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Background: There is a large variety of therapeutic agents for the treatment of vitiligo, but it still remains a challenge. Narrow-band UVB phototherapy and 308-nm excimer laser have been shown to be safe and effective for the treatment of vitiligo. Topical calcipotriol has recently been reported to enhance the efficacy of phototherapy, especially 8-methoxypsoralen plus UVA (PUVA). The goal of this study was to evaluate whether the addition of topical calcipotriol enhances the efficacy of 308-nm excimer laser in the treatment of vitiligo. Methods: The patients with symmetrical vitiliginous lesions received 308-nm excimer laser plus Calcipotriol ointment 0.005% (Daivonex®) as the intervention group and 308 nm excimer laser plus vaselin as the control group on the lesions of the right side. All patients in the two groups applied vaselin on the lesions of the left side. The evaluation of the patients was performed at baseline and at 12th week (the last laser session). SPSS version 15.0 package software was used for statistical analysis. P-values< 0.05 were accepted as statistically significant. Results: Seventy out of 83 patients completed the study. The diameter of the right side lesions (308nm excimer laser + calcipotriol) changed from 27.21 cm2 to 15.82 cm2 in the intervention group and from 27.86 cm2 to 16.02 cm2 in the control group; This difference was not statistically significant (p-value=0.74). Conclusion: Our findings showed that 308-nm excimer laser was effective and safe in the treatment of vitiligo, and that topical calcipotriol had no additive or synergistic effect.
