Banihashemi Mahnaz; Nahidi Yalda; Meibodi Naser Tayyebi; Jarrahi Lida; Livani Fatemeh; Seifnia Sahar
Abstract
Background: Pemphigus vulgaris (PV) is a rare autoimmune blistering disease of the skin and mucous membranes. Because vitamin D deficiency is associated with many immune disorders, we compared the levels of vitamin D between PV patients and healthy controls. Methods: Vitamin D level of 20 patients with ...
Read More
Background: Pemphigus vulgaris (PV) is a rare autoimmune blistering disease of the skin and mucous membranes. Because vitamin D deficiency is associated with many immune disorders, we compared the levels of vitamin D between PV patients and healthy controls. Methods: Vitamin D level of 20 patients with PV was compared with 20 healthy individuals matched for age, gender, hours spent in the sun, body mass index (BMI) and daily vitamin D intake at the same time interval. The severity of the disease was estimated according to ABSIS score. The serum level of 25-hydroxyvitamin D (25OHD) was measured by a commercial ELISA test. Results: Vitamin D deficiency in the pemphigus vulgaris group (75%) was higher than healthy controls (45%) (P = 0.053). Mean level of vitamin D in PV patients was significantly lower than healthy controls, and was in the range of vitamin deficiency (P ? 0.05). No significant relationship was observed between the severity of the PV disease and vitamin D levels (P > 0.05). Conclusions: Based on the results of the present study, the mean level of vitamin D in patients with PV was significantly lower than healthy people. Based on our findings and given the important role of vitamin D in preventing inflammatory and autoimmune diseases, vitamin D deficiency can be considered as a factor triggering the onset of PV.
Yazdanpanah Mohammad Javad; Ahmadnia Hassan; Livani Fatemeh; Shargi Mohammad Reza; Vosoughi Elham; Rahmani Shahram; Shakeri Mohammad Taghi
Volume 19, Issue 4 , 2016, , Pages 131-135
Abstract
Background: Knowledge of the frequency and distribution of dermatoses in the male genital area and the effect of circumcision on these two factors are helpful guides to a correct diagnosis. The aim of this study was to determine the prevalence of genital dermatoses in circumcised men.Methods: This cross-sectional ...
Read More
Background: Knowledge of the frequency and distribution of dermatoses in the male genital area and the effect of circumcision on these two factors are helpful guides to a correct diagnosis. The aim of this study was to determine the prevalence of genital dermatoses in circumcised men.Methods: This cross-sectional study was done on all circumcised men complaining about skin lesions in their genital area. Results: Overall, 355 men with skin lesions in their genital area were enrolled in this study. All of them were circumcised for religious reasons. The mean age of the patients was 31.4±11.5 years. Most skin lesions were seen in the age group 20-29 years (152 cases, 42%). Genital warts were the most common disease (60 cases, 16.9%) followed by dermatitis (38 cases, 10.7%), lichen planus (36 cases, 10.1%), and scabies (36 cases, 10.1%). The most common site for genital lesions was the penile shaft (155 cases, 43.7%). Genital warts were more common on the pubic area, penile shaft, and penoscrotal and peno-pubic junction. We did not observe any cases of balanitis in our study.Conclusions: Genital warts were the most common disease among our cases. Inflammatory dermatoses such as psoriasis and balanitis were less common in our population comparedwith other studies.
