M Mirshams Shahshahani; Y Sedaghat
Volume 8, suppl , 2004, , Pages 59-61
Abstract
Sometimes we see patients with disappearing vermilion totally or in some parts. It seems that the marginal skin has advanced to the lip surface with the same color. It occurs mainly in lower lip. The majority of patients had history of recurrent herpes labialis on their lips, in the same location as ...
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Sometimes we see patients with disappearing vermilion totally or in some parts. It seems that the marginal skin has advanced to the lip surface with the same color. It occurs mainly in lower lip. The majority of patients had history of recurrent herpes labialis on their lips, in the same location as disappearing vermilion. Disappearing vermilion is not accompanied by any change in consistency of labial skin. There is no symptom and most patients are unaware of it. Sometimes they refer to the physician for other reasons. Rarely patients, particularly women, complain of the disease. We collected a series of 14 cases of disappearing vermilion to evaluate this disease.
M Mirshams Shahshahani; E Aboo Saeidi
Volume 8, Issue 1 , 2004, , Pages 19-23
Abstract
Background: Epidermal nevus is a common skin hamartoma. Its definite treatment is difficult and in most cases the disease has recurrence. Objective: Evaluation of topical tretinoin 0.05% and 5 Fluorouracil (5FU) 5% in the treatment of epidermal nevus. Patients and Methods: Fifteen patients with epidermal ...
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Background: Epidermal nevus is a common skin hamartoma. Its definite treatment is difficult and in most cases the disease has recurrence. Objective: Evaluation of topical tretinoin 0.05% and 5 Fluorouracil (5FU) 5% in the treatment of epidermal nevus. Patients and Methods: Fifteen patients with epidermal nevus referred to skin clinic in Razi Hospital in Tehran whose diagnoses were confirmed by pathology examination, were treated with topical tretinoin 0.05% and 5FU 5%. Five patients were excluded because of loss to follow up and 10 patients were regularly followed. Results: Four patients were male and 6 of them were female. Their age ranged from 12 to 40 years. After 10 weeks, their nevi were flattened considerably so the patients were satisfied. There was no complication that needed to stop the treatment completely. Maintenance treatment was recommended and no recurrence was seen until the end of follow up duration. Conclusion: Topical tretinoin 0.05% and 5FU 5% are easy and inexpensive treatments for epidermal nevi, with satisfactory results and long maintenance therapy will prevent recurrence.
M Mirshams Shahshahani; S Alami Harandi; AH Ehsani
Volume 8, Issue 1 , 2004, , Pages 39-43
Abstract
Background: Urticaria is a common skin disease characterized by transient and itchy swelling. The spectrum of etiologic factors in urticaria is very wide and contains external factors such as drugs, foods and internal diseases such as infections, SLE, hormonal factors and even lymphoma. Objective: To ...
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Background: Urticaria is a common skin disease characterized by transient and itchy swelling. The spectrum of etiologic factors in urticaria is very wide and contains external factors such as drugs, foods and internal diseases such as infections, SLE, hormonal factors and even lymphoma. Objective: To determine different kinds of urticaria and different etiologic and prevocational factors in patients with urticaria. Patients and Methods: This descriptive study was carried on 120 patients with urticaria referred to Razi Hospital in Tehran in year 1376. They were evaluated in two groups: Acute and chronic urticaria, duration of 6 weeks was the limit between them. Results: About 30% of patients had acute urticaria and causes were determined in 58% of them. Upper respiratory tract infections, drugs and foods were the most common etiologic factors. In only 22% of patients with chronic urticaria, the causes were found, which included infections (Sinusitis, hepatitis B, intestinal parasitic infections), drugs (NSAIDs and Codeine) and food. Fifty percent of these patients had common urticaria, 22% of them were affected with one of the physical urticarias and in 22% of them a combination of two or more kinds of urticaria were founded. Conclusion: The most important factor in determining the cause and provocation of urticaria are taking detailed history and performing thorough clinical examination. Paraclinical studies had a little role in determining etiology of urticaria.
M Mirshams Shahshahani; H Ghani Nezhad
Volume 8, Issue 1 , 2004, , Pages 70-74
Abstract
Acne rosacea is a relatively common disease, which usually manifests in the third and fourth decades of life. It has an inflammatory condition (Papules and pustules) associated with telangiectasis, erythema and sometimes rhinophyma at the end stage of the disease. Pulsed-dye-laser (PDL), which has been ...
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Acne rosacea is a relatively common disease, which usually manifests in the third and fourth decades of life. It has an inflammatory condition (Papules and pustules) associated with telangiectasis, erythema and sometimes rhinophyma at the end stage of the disease. Pulsed-dye-laser (PDL), which has been designed for treatment of vascular lesions, may be used in treatment of acne rosacea. We present a 64-year-old man with a chronic and resistant form of acne rosacea, who underwent multiple sessions of PDL (Candela, Scleroplus) with pulse duration=1500?s, 600nm long waves and 13-14 J/cm² with 6-8 weeks intervals. Clinical follow up showed not only a reduction in edema, erythrosis and telangiectasis but also a control of inflammatory components and regression of rhinophyma. The patient didn’t take any medication during treatment and follow up period. PDL (585nm, 6-7.5 J/cm²) treatment of telangiectasis associated with rosacea had already be known, however it is the first report of successful management of chronic and resistant acne rosacea with PDL treatment by different parameters.
M Mirshams Shahshahani; M Fathabadi; AH Ehsani; M Zakeri
Volume 5, Issue 3 , 2002, , Pages 35-40
Abstract
Background: Eccrine hydrocystomas are essentially eccrine sweat gland retention cyst located in the dermis that clinically presents as small translucent cystic swelling. Objective: This study was designed to evaluate the efficacy and safety of 20% aluminum chloride hexahydrate in absolute alcohol in ...
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Background: Eccrine hydrocystomas are essentially eccrine sweat gland retention cyst located in the dermis that clinically presents as small translucent cystic swelling. Objective: This study was designed to evaluate the efficacy and safety of 20% aluminum chloride hexahydrate in absolute alcohol in the treatment of eccrine hydrocystoma. Patients and Methods: In a randomized, double-blind, placebo controlled clinical trial, 33 patients with multiple eccrine hydrocystoma referred to Tehran Razi hospital during the summer of 2000, were divided in two groups: One group received 20% aluminum chloride hexahydrate in absolute alcohol and the other one received only absolute alcohol. The patients applied the drugs to dried skin at bedtime, and washed the area in the morning. Results: Excellent or good therapeutic effects (More than 50% of improvement) were achieved in 87.5% of patients who applied 20% aluminum chloride hexahydrate but only in 17.6% of patients in control group (P<0.0001). The mean age in the first group was 42.6 years and in placebo group 45.4 years. Side effects in the first group included pruritus, burning (37.5%), xerosis and scaly (31.2%) and erythema (25%), in control group the rate of these side effects were 23.5%, 17.6%, and 11.7% consequently. Conclusion: 20% aluminum chloride hexahydrate solution is an effective and safe topical agent in the treatment of multiple eccrine hydrocystomas.
M Mirshams Shahshahani; M Danesh pazhooh; A Mirshekari
Volume 3, Issue 3 , 2000, , Pages 14-17
Abstract
Background: Pyogenic granuloma is a benign vascular proliferation that is often related to minor trauma by the patient. Objective: Evaluation of the efficacy of cryotherapy in the treatment of pyogenic granuloma. Patients and Methods: Hundred and forty-six patients with pyogenic granuloma were treated ...
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Background: Pyogenic granuloma is a benign vascular proliferation that is often related to minor trauma by the patient. Objective: Evaluation of the efficacy of cryotherapy in the treatment of pyogenic granuloma. Patients and Methods: Hundred and forty-six patients with pyogenic granuloma were treated by cryosurgery using liquid nitrogen and cotton tip applicator in an open clinical trial. This study was carried out in Razi Hospital, Tehran University of Medical Sciences, in 1377. Patients were followed for at least 3 months after complete resolution. Results: Hundred and thirty-five patients completed the study. Complete resolution was achieved in all patients. Treatment sessions ranged from one to 4 (Mean 1.6±0.8) sessions. 88.2% of patients needed only 1 or 2 treatment sessions. Recurrence of lesions occurred in 3 patients in whom retreatment led to complete resolution. Conclusion: Cryotherapy can be regarded as a completely efficient method in treatment of pyogenic granuloma.
