Sh Sadr Eshkevari; A Maboudi; E Akbari Dastak; J Golchai; J Shams Guilani; A Dorjani; N Alizadeh; O Zargari
Volume 8, Issue 2 , 2005, , Pages 104-109
Abstract
Background: Pemphigus is a serious blistering disease with considerable mortality, which heavily burdens on health care system because of the long time hospitalization. It is rare in north America but is considered as the most common immunobullous disease in eastern countries such as Malaysia and China. ...
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Background: Pemphigus is a serious blistering disease with considerable mortality, which heavily burdens on health care system because of the long time hospitalization. It is rare in north America but is considered as the most common immunobullous disease in eastern countries such as Malaysia and China. Objective: The purpose of this study was to define the epidemiologic features of pemphigus in north of Iran. Patients and Methods: One-hundred and twenty-six cases of pemphigus diagnosed based on clinicohistological findings that were hospitalized in Rasht, in north of Iran, between 1995-2001 were studied. Epidemiological data collected from their hospital records were entered in SPSS software and statistical analyses were performed by T-test, Chi-square and Pearson correlation tests. Results: Pemphigus vulgaris was the most common type (83%), followed by foliaceous (6%) and vegetans (1%). The mean age of patients was 45.6 years, with 47.2 in vulgaris and 37.8 in foliaceous group (P<0.05). There was no sex difference in mean age in vulgaris group, whereas the mean age of foliaceous group was 30.2 for females and 51.8 years for males (P<0.05). Female:male ratio was 1.5:1, with 1.44:1 for vulgaris and 1.85:1 for foliaceous groups, respectively. The oral mucosa was the first site of involvement in 63% of vulgaris cases, and 72.4% of them had widespread mucocutaneous disease at the time of hospitalization. Frequency of illness in spring (32%) was higher than other seasons. The mean time for 80% improvement of lesions in hospital was significantly higher in cases with widespread mucocutaneous lesions than cases with only skin or mucosal illness (P<0.05). Conclusion: These findings clearly demonstrate the need for continuous training of involved health workers (Dermatologists, dentists, otolaryngologists, general physicians) for early diagnosis and referral of disease, which not only could decrease the morbidity and mortality, complications rates for patients but also hospitalization costs for patients and health care system.
J Golchai; O Zargari; A Sayyadi Nejad; A Maboudi; S Geranmayeh
Volume 8, Issue 2 , 2005, , Pages 140-144
Abstract
Pseudoporphyria is an uncommon bullous disease with similar clinical and histopathological findings to porphyria cutanea tarda, in the absence of detectable porphyrin elevation. We present a 34-year-old man with clinical and histological findings compatible with porphyria cutanea tarda, whose his urinary ...
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Pseudoporphyria is an uncommon bullous disease with similar clinical and histopathological findings to porphyria cutanea tarda, in the absence of detectable porphyrin elevation. We present a 34-year-old man with clinical and histological findings compatible with porphyria cutanea tarda, whose his urinary uroporphyrin was negative and we concluded that he was a case of pseudoporphyria. Concomitant active infection with hepatitis C virus was a unique finding in this patient.
N Alizadeh; Sh Sadr Ashkevary; J Golchai; A Maboodi; AA Falahati
Volume 7, Issue 4 , 2004, , Pages 255-260
Abstract
Background: In spite of prevention and control programs, dermatophyte infections have a high prevalence worldwide. Objective: To do a descriptive study of dermatophytosis in Guilan. Patients and Methods: 217 patients whom were visited in Razi Hospital in Rasht in 1381 were screened for dermatophytosis ...
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Background: In spite of prevention and control programs, dermatophyte infections have a high prevalence worldwide. Objective: To do a descriptive study of dermatophytosis in Guilan. Patients and Methods: 217 patients whom were visited in Razi Hospital in Rasht in 1381 were screened for dermatophytosis and if had suspicious lesions, direct smear with KOH and culture were done. Results: 93 patients had positive smear (KOH 10%) and culture for dermatophytes. 50 patients were women and 43 patients were men. The most common patterns of dermatophytosis were tinea cruris (47.2%), tinea pedis (14%), tinea capitis (12.9%), onychomycosis, tinea manum, and tinea facei. Trichophyton mentagrophytes was the most common causative agent of tinea cruris that occurred more significantly in hot seasons. Conclusion: Tinea cruris was the most common type of dermatophytosis in this study. High prevalence of tinea cruris specially in women in comparison to the previous studies, may be due to occupational activity (Agriculture) and clothing of women in north of Iran.
J Golchai; O Zargari; M Gholipour; M Karbasi
Volume 7, Issue 1 , 2003, , Pages 29-32
Abstract
Background: Scabies is a contagious skin disorder and one of the most common itching dermatoses in whole of the world. Epidemiologic survey of scabies periodically done in many countries is a reflection of general status of public health in the community. Objective: To determine the prevalence of the ...
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Background: Scabies is a contagious skin disorder and one of the most common itching dermatoses in whole of the world. Epidemiologic survey of scabies periodically done in many countries is a reflection of general status of public health in the community. Objective: To determine the prevalence of the scabies and its relationship with age, sex family size and place of residence. Patients & Methods: In this observational-cross sectional study on the students of primary schools in Somea-Sara in 2000-2001, 3656 students (On the basis of stratified random sampling) were selected and examined. The diagnosis of scabies was made on the basis of clinical criteria and the demographic data were recorded. Results: 50 out of 3656 students (1.36%) were suffered from scabies. The prevalence of scabies was 1.0% in urban schools and 1.61% in rural schools, 1% in male students and 1.7% in female students. The most common age group was 8-9 years and the mean of family size in patients was 6.1 and 6.2 in urban and rural areas, respectively. Conclusion: This study indicated that prevalence of scabies is higher in lower socio-economic state and larger family size.
N Alizadeh; Sh Sadr Ashkevari; J Golchai; AA Fallahi
Volume 6, Issue 3 , 2003, , Pages 35-38
Abstract
Dermatophyte infections are one of the most common superficial fungal infections. However dermatophytes invade subcutaneous tissues rarely. We report herein a 65 year-old woman who was as a known case of rheumatoid arthritis (For 10 years) and taking immunosuppressive drugs, presented with multiple nodules ...
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Dermatophyte infections are one of the most common superficial fungal infections. However dermatophytes invade subcutaneous tissues rarely. We report herein a 65 year-old woman who was as a known case of rheumatoid arthritis (For 10 years) and taking immunosuppressive drugs, presented with multiple nodules and sinuses in the knee area. Histopathologic studies revealed PAS positive granulomas and fungal culture confirmed Trichophyton rubrum infection.
J Golchai; A Ramazanpour
Volume 5, Issue 4 , 2002, , Pages 44-47
Abstract
Although lichen planus and vitiligo are common skin disorders, their association with two other uncommon diseases, i.e. lichen sclerosus et atrophicus and disseminated superficial actinic porokeratosis, seems to be a very rare occurrence. We report herein a 70-year-old man who developed all of these ...
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Although lichen planus and vitiligo are common skin disorders, their association with two other uncommon diseases, i.e. lichen sclerosus et atrophicus and disseminated superficial actinic porokeratosis, seems to be a very rare occurrence. We report herein a 70-year-old man who developed all of these four skin disorders simultaneously.
