Nasrin Saki; Mina Bazyar Sarani; Fatemeh Sari Aslani; Mohammad Mahdi Parvizi
Abstract
Primary cutaneous diffuse large B‐cell lymphoma-leg type (PCDLBCL‐LT) is a rare malignant disease seen in older adults, especially women. In this case report, we discuss a 78-year-old man who developed erythematous indurated plaques on his left shin for about three months. The patient did not report ...
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Primary cutaneous diffuse large B‐cell lymphoma-leg type (PCDLBCL‐LT) is a rare malignant disease seen in older adults, especially women. In this case report, we discuss a 78-year-old man who developed erythematous indurated plaques on his left shin for about three months. The patient did not report pruritus, weight loss, night sweats, fever, or chills. There was no lymphadenopathy, splenomegaly, or hepatomegaly on the physical examination. A local tissue biopsy was taken from the plaques, confirming the diagnosis of PCDLBCL‐LT via immunohistochemistry. The patient was referred to an oncologist to begin additional evaluation and treatment. According to the literature, chemotherapy with or without adjuvant radiotherapy is the first treatment choice for PCDLBCL‐LT. Monotherapy with rituximab could be considered in some patients with this condition, but the disease may relapse in a short period.
Behnam Avandi; Mehdi Ghahartars; Navid Moradi Kashkooli; Najmeh Ahramiyanpour; Mohammad Mahdi Parvizi
Abstract
Erythroderma or generalized scaling dermatitis is a condition marked by redness and scaling of more than 90% of the body surface. This study aimed to review the epidemiological and clinical features of erythroderma patients hospitalized in the Dermatology Ward of Shahid Faghihi Hospital, Shiraz, Iran. ...
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Erythroderma or generalized scaling dermatitis is a condition marked by redness and scaling of more than 90% of the body surface. This study aimed to review the epidemiological and clinical features of erythroderma patients hospitalized in the Dermatology Ward of Shahid Faghihi Hospital, Shiraz, Iran. This retrospective cross-sectional was conducted from 2001 to 2017 using patient records. All patients with a diagnosis of erythroderma on record were included in the survey, and those whose data were missing or were not compatible with the clinical diagnosis were excluded. Data were analyzed with SPSS version 22 and Stata version 14.2. Overall, 217 erythroderma patients were admitted to this ward, including 119 (54.8%) men and 98 (45.2%) women. The mean age of the patients was 47.27 ± 19.68 years (range: 4-92 years). Moreover, the most frequent cause of erythroderma was drug reaction (67%); lamotrigine, with a frequency of 12 patients, was the most prevalent prescribed medication in patients with drug reaction-induced erythroderma. The mean duration of hospital stay was 6.64 ± 4.50 days; this parameter was directly associated with the erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) level. Pruritus (41.9%) and fever (15.2%) were the most frequent clinical manifestations among these patients. As erythroderma is a dermatologic condition that medications can induce, patients should be informed about the warning signals and course of the disease before certain medications are prescribed.
Leili Amani; Fatemeh Fadaei; Mohammadreza Shams Ardakani; Mehran Mirabzadeh Ardakani; Seyede Nargess Sadati Lamardi; Laila Shirbeigi
Abstract
Background: Skin conditions are among the most common health problems worldwide and are associated with immense psychological, social, and financial burdens. Atopic dermatitis, alopecia, eczema, diabetic ulcers, and abscesses are common acute or chronic conditions, which are increasing ...
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Background: Skin conditions are among the most common health problems worldwide and are associated with immense psychological, social, and financial burdens. Atopic dermatitis, alopecia, eczema, diabetic ulcers, and abscesses are common acute or chronic conditions, which are increasing dramatically in prevalence due to industrialization and unhealthy lifestyle habits. The use of complementary and alternative medicine to treat skin diseases has been increasing in recent years. Methods: This review focuses on proposed skin conditions for leech therapy as mentioned by Avicenna, a great Iranian philosopher and physician (980-1037 AD)in the Canon of Medicine. Electronic databases including PubMed, Scopus, and Google Scholar were searched for clinical studies on treatment protocols in this book to compare them with recent clinical trials involving leech therapy. Results: Investigation of traditional Iranian medicine literature can lead to the identification of natural medicines for the management of skin problems. Leech saliva contains anti-coagulative, antiaggregative, and vasodilatory components. Conclusions: In addition to the annelid’s mechanical ability to extract blood, leeches can contribute to patients’ health while posing minimal risks.
Dadras Mohammad Shahidi; Golfeshan Atefeh; Younespour Shima
Volume 18, Issue 1 , 2015, , Pages 16-19
Abstract
Background: The ABO blood group antigens play a role in thepathophysiology of some diseases and several researches haveinvestigated this relationship in the field of dermatology. In thepresent study, an attempt was made to find the distribution ofblood types in patients with pemphigus vulgaris and chronicplaque ...
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Background: The ABO blood group antigens play a role in thepathophysiology of some diseases and several researches haveinvestigated this relationship in the field of dermatology. In thepresent study, an attempt was made to find the distribution ofblood types in patients with pemphigus vulgaris and chronicplaque type psoriasis.Method: Fifty patients with chronic plaque type psoriasis, 50patients with pemphigus vulgaris and 100 healthy persons ascontrol group, were selected as the study population. ABO bloodgrouping was determined by the cell type tube test method, usingstandard commercial anti/A, anti/B and 5% suspension of redblood cells. Chi square test was used to compare the frequencyof ABO blood groups in patients and control groups.Result: Among the 50 patients with psoriasis, 21 (42%) hadblood group O, 15 (30%) blood group A, 10 (20%) blood groupB and 8 (4%) had blood group AB. Among the 50 patients in thepemphigus group, 22 (44%) had blood group O, 19 (38%) bloodgroup A, 8 (16%) blood group B and 1 (2%) had blood groupAB. The distribution of blood groups in patients with these twodiseases was not significantly different from the control group.Conclusion: Despite some researches, which found associationsbetween blood group antigens and psoriasis or pemphigus, thisstudy did not find any such relationship.
Handjani Farhad; Kalafi Amir
Volume 16, Issue 4 , 2013, , Pages 128-131
Abstract
Background: Chronic skin diseases such as vitiligo and psoriasis can impair the quality of life in the patients with these diseases. The impact of chronic and/or severe skin diseases on the lives of family members of the affected patients has only recently been addressed. The tool used for this assessment ...
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Background: Chronic skin diseases such as vitiligo and psoriasis can impair the quality of life in the patients with these diseases. The impact of chronic and/or severe skin diseases on the lives of family members of the affected patients has only recently been addressed. The tool used for this assessment is the Family Dermatology Life Quality Index (FDLQI). The aim of this study was to use the FDLQI to assess the impact of four skin diseases (pemphigus, psoriasis, vitiligo, and cutaneous leishmaniasis) on family members of the affected patients.Method: Fifty healthy family members of 50 patients with pemphigus, psoriasis, vitiligo, and cutaneous leishmaniasis were included in this study. The patients had to have an extensive disease with disease duration of at least one month. One family member of each patient completed the 10- item Persian version of the FLDQI questionnaire. The score of this index ranged from 0 to 30.Result: The mean duration and mean FDLQI score of the diseases were as follows: psoriasis (mean duration=4.1±2.7, mean FDLQI score=14.7±5.01), pemphigus (mean duration=3.6±2.3, mean FDLQI score=15.4±4.7), vitiligo (mean duration=5.1±4.05, mean FDLQI score=14.4±5.08) and cutaneous leishmaniasis (mean duration=0.62±0.23, mean FDLQI score=12.0±4.3). There was no significant difference among the groups (p=0.562). In addition, no strong correlation was observed between the mean duration of the disease and mean FDLQI scores for each condition (r=0.051, p=0.726).Conclusion: This small-scale study demonstrated that although not statistically significant, inflammatory diseases like pemphigus had a higher FDLQI score when compared to non-inflammatory conditions like vitiligo and short-term conditions such as leishmaniasis.
Moin Athar; Dowlati Yahya
Volume 9, Issue 4 , 2006, , Pages 343-349
Abstract
Background and aim: Skin diseases among pilgrims are considered to be one of the possible health problems. Data supporting this observation are scanty. The aim of this study was to report the most common skin diseases seen in Hajj season. Materials and Methods: Data regarding skin diseases were collected ...
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Background and aim: Skin diseases among pilgrims are considered to be one of the possible health problems. Data supporting this observation are scanty. The aim of this study was to report the most common skin diseases seen in Hajj season. Materials and Methods: Data regarding skin diseases were collected from piligrims whom were examined and diagnosed clinically at the skin clinics of Iran in Saudi Arabia in 1993 and 1999. Results: During the Hajj season in 1999, 362 patients were seen. The most common groups of diseases were eczemas of different types and related conditions (35.9%), mechanical and thermal injury (17.6%) and infections (16.5%), accounted for more than 70% of cases. During Hajj season in 1993, 560 patients were seen. The most common groups of diseases were infections (19.3%), eczema and related conditions (18.6%) and disorders of skin appendages (16.4%), accounted for about 54.2% of observed skin diseases.Conclusion: The finding of these most common skin disorders is important in training programmes and delivery of service for care of pilgrims, because they are preventable, easily diagnosed and curable in the majority of patients.
H Ansarin; S Abbasi Moin
Volume 5, Issue 1 , 2001, , Pages 34-38
Abstract
Background: Pruritic skin disorders are one of the most common disorders in elderly. Objective: To find out the prevalence of pruritic skin disorders in the elderly residing in Kahrizak Institute in Tehran. Patients and Methods: In this descriptive, cross sectional survey, all the elderly over 60 years ...
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Background: Pruritic skin disorders are one of the most common disorders in elderly. Objective: To find out the prevalence of pruritic skin disorders in the elderly residing in Kahrizak Institute in Tehran. Patients and Methods: In this descriptive, cross sectional survey, all the elderly over 60 years of age without dementia residing in Kahrizak Institute in Tehran in the first 6 months the year 1379 were studied for the presence of 9 pruritic skin disorders including xerosis, eczema, lichen simplex chronicus, infections, urticaria, insect bite and scabies, psoriasis vulgaris, drug eruption and anogenital pruritus. Questionnaires were completed for persons who complained from pruritus, based on general examinations. Statistical analysis was done by using SPSS/PC software. Results: Out of 734 elderly included in the study, 161 (22%) had pruritus including 89 women (54%) and 72 men (46%). The most common cause of pruritus in both sexes were xerosis or senile pruritus. Eczemas were more common in males and the most common type was seborrheic dermatitis. Diabetes mellitus was the most common systemic disorder associated with pruritus. Conclusion: Pruritic skin disorders are very common in elderly. The responsible organizations must pay attention to this fact and plan better institution and medical facility for this precious group of our society.
S Shamsaddini
Volume 3, Issue 4 , 2000, , Pages 38-42
Abstract
What shall we do when we have done everything we could for the diagnosis and treatment of a patient, but were not successful? What shall we do when there is no definite treatment for a patient? What shall we do when we have no diagnosis or treatment for a patient? Some useful suggestions are presented ...
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What shall we do when we have done everything we could for the diagnosis and treatment of a patient, but were not successful? What shall we do when there is no definite treatment for a patient? What shall we do when we have no diagnosis or treatment for a patient? Some useful suggestions are presented here to get rid of these situations.
