Maryam Khalili; simin Shamsi Meymandi; Saman Mohammadi; Mahin Aflatoonian; Elahe Kooshesh
Abstract
Background: Granulomatous skin lesions are characterized by aggregation of activated histiocytes. Granulomatous skin lesions are classified as xanthomatous, necrobiotic, tuberculoid, sarcoidal, and foreign body types. This study evaluates the clinicopathological features of patients with granulomatous ...
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Background: Granulomatous skin lesions are characterized by aggregation of activated histiocytes. Granulomatous skin lesions are classified as xanthomatous, necrobiotic, tuberculoid, sarcoidal, and foreign body types. This study evaluates the clinicopathological features of patients with granulomatous skin lesions.Methods: We conducted a cross-sectional study of 232 skin biopsies diagnosed as granulomatous skin lesions over ten years from patients referred to Afzalipour Hospital, Kerman, Iran. Demographics, clinical features of lesions, and pathological characteristics were recorded. Then, the correlation of the final diagnosis with the demographic and clinical features of the patients was assessed via the independent t-test and chi-squared test.Results: Most patients were in their third decade of life, with a male-to-female ratio of 1.05 to 1. The most common types of granuloma were tuberculoid (60.3%), necrobiotic (12.5 %), and foreign body type (11.2%). Infectious disease was the most common cause of granulomatous lesions (64.2 %); leishmaniasis constituted approximately 96% of cases. The most common causes of noninfectious granulomatous skin diseases were foreign body granuloma (26.2%), granuloma annulare (23.2%), and xanthogranuloma (12.1%). There was a significant correlation between dermatologic disease type and disease duration (P = 0.024).Conclusion: In the current study, the most common type of granuloma was tuberculoid, followed by necrobiotic and foreign body type granulomas. Infectious diseases were the most common cause of granulomatous skin lesions. Furthermore, the most common granulomatous skin diseases were leishmaniasis, foreign body granuloma, and granuloma annulare. The least common granulomatous skin lesions were sporotrichosis and gout.
Muhammed Mukhtar
Abstract
An ingrown toenail is a painful disorder of the lateral nail fold associated with inflammation, infection, and granuloma formation. Various conservative modalities have been described to reduce the pressure of an ingrown nail on its gutter. The invasive option is preferred for severe ingrown nails (grade ...
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An ingrown toenail is a painful disorder of the lateral nail fold associated with inflammation, infection, and granuloma formation. Various conservative modalities have been described to reduce the pressure of an ingrown nail on its gutter. The invasive option is preferred for severe ingrown nails (grade III). Here an innovative, less invasive technique is described to treat severe grades of ingrown nails with the use of mosquito artery forceps and cyanoacrylate glue. The glue on curing becomes a hard cast that blunts and insulates the nail from its gutter, protecting the gutter from nail injury. The glue is hygroscopic and antiinfective, making the gutter dry, healthy, and maceration-free. The ingrown nail becomes asymptomatic within half an hour of splinting, and the granuloma heals within 3 to 6 weeks. Thus chemical splinting with cyanoacrylate glue is a novel and fast conservative technique for treating severe grades of ingrown toenails in outpatient care units.
M Mir Shams Shahshahani; M Ghiasi
Volume 8, suppl , 2005, , Pages 69-72
Abstract
Between 20% and 35% of patients with systemic sarcoidosis have skin lesions. One of the unusual cutaneous presentations of sarcoidosis is a granulomatous tattoo reaction that may present alone or with other features of sarcoidosis. We present a case of sarcoidosis whom presented with multiple nodules ...
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Between 20% and 35% of patients with systemic sarcoidosis have skin lesions. One of the unusual cutaneous presentations of sarcoidosis is a granulomatous tattoo reaction that may present alone or with other features of sarcoidosis. We present a case of sarcoidosis whom presented with multiple nodules on tattood skin accompanied with facial pulsy, parotid enlargement and uveitis.
