Saeedeh Farajzadeh; Mahin Aflatoonian; Saman Mohammadi; Hamid Sharifi; Maryam Khalili
Abstract
Background: Hyperhomocysteinemia and vitamin D deficiency maybe involved in the pathogenesis of vitiligo. This study comparedthe serum levels of vitamin D, homocysteine, vitamin B12, andfolic acid between vitiligo-affected children and healthy children.Methods: Using a case-control design, 30 children ...
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Background: Hyperhomocysteinemia and vitamin D deficiency maybe involved in the pathogenesis of vitiligo. This study comparedthe serum levels of vitamin D, homocysteine, vitamin B12, andfolic acid between vitiligo-affected children and healthy children.Methods: Using a case-control design, 30 children with vitiligoand 30 age and sex-matched healthy children were enrolledfrom April 2018 to August 2020. Serum levels of vitamin D,homocysteine, vitamin B12, and folic acid were analyzed in bothgroups during the same season of the year. Additionally, theassociation between serum levels of these factors with demographicand clinical features of the children (collected by interview andphysical examination) was evaluated. Data were analyzed usingthe independent T-test, Fisher’s exact test, and chi-squared test.Results: The vitiligo group had significantly lower vitamin Dand folic acid serum levels compared with the control group[95% CI -19.87 to -2.96 and -4.15 to -4.18, respectively]. Amongpatients, the vitamin D level was negatively correlated with age(r = -0.459, P = 0.011) and disease duration (r = -0.373, P = 0.042).Moreover, there was a significant association between vitiligoactivity and serum homocysteine levels (P = 0.027).Conclusion: Routine measurement of vitamin D and folic acidserum levels might be suggested, especially in children withlong-standing disease. Monitoring the homocysteine level maybe beneficial, particularly in children with progressive vitiligo.
Farnoosh Seirafianpour; Farzaneh Mashayekhi; Milad Dodangeh; Forough Seifi Gharabaghloo; Masoud Pourghahramani Koltapeh; Ali Jamshidi Naeini; Rohollah Valizadeh; Davood Lakestani; Samaneh Mozafarpoor; Azadeh Goodarzi
Abstract
Background: About 20% of patients with coronavirus disease2019 (COVID-19) present with mucocutaneous eruptions. Earlyskin or dermatological manifestations can help pediatriciansprevent the spread of the disease by suspecting COVID-19 inasymptomatic or minimally symptomatic patients.Methods: PubMed, Scopus, ...
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Background: About 20% of patients with coronavirus disease2019 (COVID-19) present with mucocutaneous eruptions. Earlyskin or dermatological manifestations can help pediatriciansprevent the spread of the disease by suspecting COVID-19 inasymptomatic or minimally symptomatic patients.Methods: PubMed, Scopus, Embase, Google Scholar, and theNottingham University website were searched on Sep. 1st, 2020,to retrieve studies regarding COVID-19-related mucocutaneousmanifestations in patients under the age of 18.Results: Data were extracted from 76 articles including 38,387 cases.Chilblain/pernio-like lesions were the most common dermatologicalmanifestation, followed by multisystem inflammatory syndrome inchildren (MIS-C)/Kawasaki-like syndrome. Most dermatologicalsigns were self-limited, presenting before, simultaneously with,or after other COVID-19 manifestations. In 40% of the affectedchildren, these signs were the sole presentation of COVID-19.Conclusion: During the COVID-19 pandemic, each newmucocutaneous event in children, especially acral lesions withvascular color, should be considered a possible indicator ofCOVID-19.
Caroline Oktarina; Danny Surya; Putu Martha Gerynda Sukma; Teguh Hopkop Putera Manurung; Sandra Widaty
Abstract
Background: Scabies is an infestation caused by Sarcoptes scabiei var. hominies, prevalent in children with poor nutritional status and hygiene, particularly in overcrowded communities. Indonesia has 14.5% cases of the double burden of malnutrition among school-aged children. As there has been no study ...
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Background: Scabies is an infestation caused by Sarcoptes scabiei var. hominies, prevalent in children with poor nutritional status and hygiene, particularly in overcrowded communities. Indonesia has 14.5% cases of the double burden of malnutrition among school-aged children. As there has been no study establishing the role of nutritional status in the occurrence of scabies, this study aims to investigate the association between body mass index (BMI) and height with scabies infestation in an Islamic boarding school in Indonesia.Methods: This was a cross-sectional study conducted in an Islamic boarding school in Indonesia with children aged 11-17 years old as participants. Physicians performed anthropometry measurements, and a dermatologist confirmed the diagnosis of scabies through history taking and physical examination. Logistic regression was used to analyze the association between BMI and height and the prevalence of scabies.Results: Of 287 subjects, 135 (47%) were diagnosed with scabies, with a male predominance (66.1%). Most of the subjects had normal weight (76.7%) while 20 (7%) were underweight, and 153 subjects (53.3%) had short stature. Male subjects were four times more likely to be infested by scabies (P < 0.001). Obese and short subjects were 4 and 1.67 times more likely to develop scabies, respectively.Conclusion: Poor nutritional status represented by BMI and height cannot be regarded as an independent risk factor for scabies, while environmental factors might be the most crucial factors in the development of scabies. A holistic approach addressing these factors should be implemented to eradicate scabies in addition to appropriate pharmacological management.
Manjunath Shenoy; Amina Asfiya; Malcolm Pinto
Abstract
Pyogenic granuloma (PG) is a common, acquired tumor-like growth occurring on skin/mucous membranes. It is prevalent in the pediatric age group. It is benign in nature and is caused by chronic low grade trauma. It presents as pink to red elevated pedunculated or sessile mass. There ...
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Pyogenic granuloma (PG) is a common, acquired tumor-like growth occurring on skin/mucous membranes. It is prevalent in the pediatric age group. It is benign in nature and is caused by chronic low grade trauma. It presents as pink to red elevated pedunculated or sessile mass. There are various treatment modalities including surgery, cryotherapy, laser, electrocautery, etc. However, the therapeutic effects are limited with high recurrence rates. The use of sclerotherapy for the treatment of pyogenic granuloma in children is not commonly reported. We present a case of PG on the scalp successfully treated with intralesional injection of sodium tetradecyl sulfate.
Farajzadeh Saeedeh; Bazargan Nasrin; Shahesmaeili Armita; Shahrbabaki Azam Gholami; Fekri Ali Reza
Volume 13, Issue 2 , 2010, , Pages 33-36
Abstract
Background: The role of food allergy in atopic dermatitis (AD) is controversial. The aim of this study was to determine the frequency of food allergens in children with AD. Method: Fifty one atopic dermatitis children aged 6 months to 5 years entered our study. The severity of AD was determined by scoring ...
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Background: The role of food allergy in atopic dermatitis (AD) is controversial. The aim of this study was to determine the frequency of food allergens in children with AD. Method: Fifty one atopic dermatitis children aged 6 months to 5 years entered our study. The severity of AD was determined by scoring index of AD (SCORAD). Skin prick test (SPT) was done using 15 allergens including the white of the egg, yolk, peanut, kiwi, strawberry, cow's milk, walnut, fish, banana, wheat, orange, tomato, cereals, apple and cocoa. Results: Thirty four patients (66.7%) had a positive reaction to one or more allergens and in 17 patients (33.3%), the SPT was negative to all allergens. Eleven patients (21.6%) had a positive SPT to one food allergen, 9 patients (17.6%) to two allergens, 9 patients (17.6%) to three allergens, 3 patients (5.9%) to four allergens, 1 patient (2%) to seven allergens and 1 patient (%2) to ten allergens. The most common food allergen among 15 allergens was white egg in 19 patients (37.3%). Yolk was the second most common allergen in 11 patients (21.6%). The relationship between the severity of the SPT with AD severity was observed only for cow's milk, which showed a reverse relationship (R=-0.337). Conclusion: White egg was the most common allergen in all ages and both sexes. Food allergens may play a role in the pathogenesis of atopic dermatitis.
Farajzadeh Saideh; Esfandiarpour Iranj; Pourhamzadeh Bahareh
Volume 10, Issue 4 , 2007, , Pages 320-328
Abstract
زمینه و هدف: از آن جایی که بیماری های پوستی در دوران کودکی از جهت های زیادی با افراد بالغ متفاوت است لذا تعیین الگوی شیوع بیماری های کودکان نقش مهمی در تعیین راه کارهای ...
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زمینه و هدف: از آن جایی که بیماری های پوستی در دوران کودکی از جهت های زیادی با افراد بالغ متفاوت است لذا تعیین الگوی شیوع بیماری های کودکان نقش مهمی در تعیین راه کارهای درمانی و پژوهشی دارد. هدف از این مطالعه تعیین الگوی شیوع بیماری های پوستی اطفال در کودکان مراجعه کننده به کلینیک های تخصصی پوست شهر کرمان بود. روش اجرا: در این مطالعه که از نوع توصیفی- تحلیلی، مقطعی است 937 نفر از کودکان زیر 16 سالی که به کلینیک های تخصصی پوست شهر کرمان در فاصله شهریور تا اسفند 85 مراجعه کرده بودند وارد مطالعه شدند. برای هر یک از بیماران پرسش نامه شامل سن، جنس، محل زندگی، تحصیلات والدین و نوع بیماری پوستی تکمیل شد. بیماری های پوستی توسط متخصص و بر اساس علایم و معاینه بالینی و روش های پاراکلینیک شامل بیوپسی، اسمیر و کشت باکتریال، اسمیر قارچ، Woods lamp و Tzank test تشخیص داده شد. یافته ها: طبق نتایج به دست آمده در مجموع درماتیت ها و عفونت های پوستی شایع ترین بیماری ها را تشکیل می داد. در بین درماتیت ها، درماتیت آتوپیک و سبورئیک از بقیه شایع تر و درماتوز پلانتار جوانان و لیکن سیمپلکس مزمن از بقیه نادرتر بود. در بین عفونت ها هم، عفونت های ویروسی و انگلی شایع تر از انواع باکتریایی و قارچی بود. در مقایسه بین دخترها و پسرها خال های ملانوسیتی به طور معنی داری در دخترها بیش تر از پسرها بود (02/0>p). اختلال های کراتینیزاسیون در کودکان مادران تحصیل کرده کم تر مشاهده شد (006/0>p). نتیجه گیری: طبق نتایج به دست آمده، درماتیت آتوپیک شایع ترین بیماری در این مطالعه بود که علت آن ممکن است به دلیل تغییر رژیم غذایی، عوامل پری ناتال و افزایش تماس با آلرژن های محیطی باشد. بیماری شایع بعدی عفونت های پوستی بود که این مطلب نشانه اهمیت توجه به مسایل بهداشتی این گروه سنی است.
MA Mapar; H Nazari; Kh Siavashi
Volume 3, Issue 4 , 2000, , Pages 23-28
Abstract
Background: Determination of the prevalence of diseases is an important step in health programs. Objective: To determine the prevalence of skin diseases in primary school students in Ahwaz. Patients and Methods: This cross-sectional study was done in March and April 1995 (Esfand 1373, Farvardin 1374) ...
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Background: Determination of the prevalence of diseases is an important step in health programs. Objective: To determine the prevalence of skin diseases in primary school students in Ahwaz. Patients and Methods: This cross-sectional study was done in March and April 1995 (Esfand 1373, Farvardin 1374) in Ahwaz. 3000 male and 3000 female primary school students were examined for the presence of skin disease by a physician. This sample comprised 5 percent of total primary school students of Ahwaz. Diagnosis was made on clinical findings, laboratory examinations and skin biopsy, if needed. Results: The most common skin diseases were: pityriasis alba, acne, freckle, keratosis pilaris, pediculosis capitis, chicken pox, wart, impetigo, herpes simplex and leishmaniasis. The most common diseases in girl were acne and pediculosis capitis and in boys were acne and warts. Also the prevalence of diseases was related to the economic status of students. Conclusion: Skin diseases are common in primary school students in Ahwaz. The prevalence of certain skin diseases was related to the sex and economic status of the students.
