Mahsa Ghajarzadeh; Maryam Ghiasi; Shahrbanoo Kheirkhah
Volume 14, Issue 4 , 2011, , Pages 140-143
Abstract
Background: Alopecia Areata (AA) is a skin disease which affects 0.2 % of general population. Unlike its little physical impairment, Alopecia areata causes a lot of cosmetic problems but most clinicians do not pay attention to mood disorders and the impaired quality of life as the consequences of disease. ...
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Background: Alopecia Areata (AA) is a skin disease which affects 0.2 % of general population. Unlike its little physical impairment, Alopecia areata causes a lot of cosmetic problems but most clinicians do not pay attention to mood disorders and the impaired quality of life as the consequences of disease. Objectives: To evaluate depression and quality of life in Iranian patients with Alopecia areata . Methods: From January 2009 until January 2010 one hundred alopecia areata patients who were randomly selected (through simple random selection) from the outpatient clinic of Razi Hospital were asked to answer valid and reliable instruments such as Beck Depression Inventory (BDI), SF-36 and DLQI (Dermatology Life Quality Index) questionnaires. Results: The mean scores of BDI, SF-36and DLQI of the patients were 14.4±9.7, 68.04 ±15.1 and 6.4±5.5, respectively. The BDI score was significantly different between male and female participants (F=18.1 ±11.2 vs. M=12.7±8.5, p=0.01) but SF -36 and DLQI scores did not significantly differ between the two gender groups. Duration of the disease, BDI and age had no significant correlation with DLQI scores. Patients with extensive beard involvement had the highest BDI score and the lowest SF-36 score. Conclusion: mood disorders should be considered in Alopecia areata patients to address the risk of markedly impaired quality of life
Mohammad Dehghan; Sepideh Hajian; Nazila Alborzi; Afsaneh Borgheyee; Amir Hussein Noohi
Volume 12, Issue 1 , 2009, , Pages 13-15
Abstract
Background: Dermatophytes are a group of closely related fungi that invade keratinized tissues (skin, hair and nails) of humans and animals and produce infections called dermatophytosis. Our objective was to determine causative agents of dermatophytosis in Gorgan, North of Iran. Methods: Data was based ...
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Background: Dermatophytes are a group of closely related fungi that invade keratinized tissues (skin, hair and nails) of humans and animals and produce infections called dermatophytosis. Our objective was to determine causative agents of dermatophytosis in Gorgan, North of Iran. Methods: Data was based on collecting specimens from 1108 patients clinically suspected to have fungal infection during five years from 2003 through 2007. Specimens were collected from hair, nail and skin and were investigated by direct examination and cultured in Sabouraud dextrose agar. Fungal colonies were identified by macroscopic and microscopic examination and supplementary tests. Results: 351 samples out of 1108 were positive for dermatophytes and 277 ones had positive cultures. Epidemophyton floccosum was the most frequent species (70.4%) followed by Trichophyton rubrum (14.5%) and Microsporum audouinii (7.2%). Regarding the location of the lesions, groin and nails were the most frequent sites that developed dermatophytosis in the majority of the patients. Conclusion: Dermatophytosis is probably still one of the most infectious diseases in Iran. The anthropophilic (E.fluoccosum) and zoophilic (T. rubrum) species were the most common causes of dermatophyte of tinea in Gorgan, north of Iran. The frequency of tinea was higher in females and tinea cruris showed a remarkably increasing rate and can be an important public health issue in Gorgan.
Seirafi Hasan; Farnaghi Farshad; Shams Negin; Davari Parastoo; Gorouhi Farzam
Volume 11, Issue 4 , 2008, , Pages 156-158
Abstract
Background: Inpatient therapy in dermatology offers a number of advantages in several ways i.e. careful monitoring of patients’ conditions, improvement of their skin lesions under the supervision of trained staff, absence of domestic pressure and increasing the quality of patients’ life index. ...
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Background: Inpatient therapy in dermatology offers a number of advantages in several ways i.e. careful monitoring of patients’ conditions, improvement of their skin lesions under the supervision of trained staff, absence of domestic pressure and increasing the quality of patients’ life index. The objective of this study was to describe the patterns of admission for patients with dermatological diseases in Iran Methods: In this retrospective study, data were collected by completing a questionnaire for 481 patients admitted to Razi skin hospital in Tehran during 18 months. Results: The mean age of admitted patients was 44.03 years ± 19.15. Bullous diseases (39.92%), psoriasis (20.79%), dermatitis (9.56%) and neoplasms (6.65%) were found as the most common reasons for admission. The mean duration of hospitalization was 22.79 days and neoplasms had the highest mean hospitalization period. Conclusions: Patient's admission patterns differ from country to country and there should be prioritizing plans to reach better results.
F Jafari; Sh Moradi; MA Nilforoush Zadeh; R Derakhshan; N Ansari
Volume 9, Issue 3 , 2006, , Pages 211-216
Abstract
Background and aim: Cutaneous leishmaniasis is an endemic disease in Iran. Although there are many different treatments for this disease, there is not any effective treatment yet. Since there has been a number of different reports on the effectiveness of Cassia fistula plant in the treatment of leishmaniasis, ...
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Background and aim: Cutaneous leishmaniasis is an endemic disease in Iran. Although there are many different treatments for this disease, there is not any effective treatment yet. Since there has been a number of different reports on the effectiveness of Cassia fistula plant in the treatment of leishmaniasis, the efficacy of concentrated boiled extract and hydro alcoholic extract of Cassia fistula on the leishmaniasis disease was compared with intralesional injection of Glucantime in this study.Materials and Methods: In this randomized clinical trial a total of 165 patients, 6 to 60 years old, who had a positive leishmania smear refered to the Isfahan Skin and Leishmaniasis Research Center were divided into three groups using list of random numbers and were treated with: concentrated boiled extract of Cassia fistula, hydroalcholic extract of Cassia fistula, or intralesional injection of Glucantime. The patients were treated for 4 weeks and followed for three months after the study started. The efficacy of treatment was reported as complete cure, partial improvement and no improvement on the basis of clinical and parasitological evidence.Results: In the present study 63/6% of patients treated with the concentrated boiled extract, 52/7% of the hydroalcoholic extract and 45/5% of the Glucantime group were men. 22 patients (40%) of the concentrated boiled extract of Cassia fistula, 20 pateints (36/4%) of the hydroalcoholic extract of Cassia fistula group and 36 patients (65/5%) of the Glucantime group showed complete cure. The efficacy in the third group was much more than the first (P<0.02) and second groups (P<0.005), but there was not any difference between concentrated boiled extract and hydroalcoholic extract of Cassia fistula.Conclusion: The results of this study showed that this plant might be used topically along with Glucantime for decreasing the time and dose of treatment with Glucantime.
MA Nilforoush Zadeh; G Sadeghian; F Jafari; AR Firooz; Sh Moradi; R Derakhshan
Volume 9, Issue 1 , 2006, , Pages 35-39
M Maleki; Z Javidi; V Soofi Zadeh; S Ebrahim Zadeh
Volume 9, Issue 1 , 2006, , Pages 40-45
MA Nilfroush Zadeh; N Anasri; R Derakhshan
Volume 8, Issue 6 , 2006, , Pages 457-461
Abstract
Background and aim: Pentavalent antimony compounds are the first line treatment for cutaneous leishmaniasis. Clinical resistance to pentavalent antimony in the form of meglumine antimoniate (Glucantime) has been recognized as a problem in leishmaniasis. Herein, clinical response to Glucantime were studied ...
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Background and aim: Pentavalent antimony compounds are the first line treatment for cutaneous leishmaniasis. Clinical resistance to pentavalent antimony in the form of meglumine antimoniate (Glucantime) has been recognized as a problem in leishmaniasis. Herein, clinical response to Glucantime were studied in patients suffered from cutaneous leishmaniasis.Materials and Methods: In a cross-sectional study 370 patients with cutaneous leishmaniasis were treated with systemic Glucantime, 50 mg/kg/day, for 2 to 3 weeks. They were visited weekly for 3 weeks and also followed up for 3 months after treatment was completed. The clinical and parasitological response to this treatment was evaluated, and classified into partial and complete response and failure to treatment. Results: Two hundred forty-seven men and 123 women were followed up. The mean age was 36.7±16 years. There were 64.1% partial response after 2 weeks and 73% partial response at the third week of treatment. 11.6% of lesions were not cured after 3 weeks of treatment and 8.1% were not still cured 12 weeks thereafter.Conclusion: Clinical resistance to Glucantime is an important problem. The mechanisms of resistance and using drug combinations are needed to be considered.
M Adabi; AR Firoozjahi; M Ghasemi
Volume 8, suppl , 2004, , Pages 21-25
Abstract
Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized ...
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Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized stage of erythema chronicum migrans. The diagnosis was confirmed by the presence of serum antibody using ELISA method.
AR Fekri; S Shamsaddini; A Maghsoodloo Nejad
Volume 3, Issue 4 , 2000, , Pages 7-17
Abstract
Background: Beta-thalassemia major (BTM) is a genetic disorder, which is common in Kerman province of Iran. New methods of care has increased their survival. Objective: The objective of this descriptive study was to assess the frequency of skin and mucosal complications of BTM patients. Patients and ...
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Background: Beta-thalassemia major (BTM) is a genetic disorder, which is common in Kerman province of Iran. New methods of care has increased their survival. Objective: The objective of this descriptive study was to assess the frequency of skin and mucosal complications of BTM patients. Patients and Methods: All BTM patients referred to Kerman-Darman Hospital in 1377 (150 cases) were evaluated. Dermatologic signs and symptoms were diagnosed by physical examination and serum ferritin levels were measured. Results: Skin hyperpigmentation (65.3%), mucosal hyperpigmentation (41.3%), coarse nail (34%) and coarse hair (20.7%) were the most common signs. They were related to the age and serum ferritin levels but sex of patients and dose of desferral had no significant relation with skin complications. Conclusion: Skin and mucosal lesions are common in BTM. An exact exam and control of serum ferritin level with desferral is recommended to prevent skin complications.
D Farhud; F Azizi
Volume 1, 3-4 , 1998, , Pages 40-42
Abstract
Harlequin Ichthyosis is a dermal disorder that always lead to an early death after birth. Although the clinical characteristics of this disorder has been described perfectly but the molecular basis of which isn’t clear well. Harlequin fetus is an Autosomal recessive trait and prenatal diagnosis ...
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Harlequin Ichthyosis is a dermal disorder that always lead to an early death after birth. Although the clinical characteristics of this disorder has been described perfectly but the molecular basis of which isn’t clear well. Harlequin fetus is an Autosomal recessive trait and prenatal diagnosis is possible by embryo skin biopsy after fetoscopy. This case was a male newborn who died 4 days after the birth. The parents of the infant have a consanguineous marriage and live in a village around Shahrood (East of Iran). This family had also another infant with same disorder, who died also on 4 days of her life but they have a 7 years old healthy girl.
R Yaghoobi; N Hoghooghi Rad
Volume 1, Issue 1 , 1997, , Pages 19-23
Abstract
Cutaneous leishmaniasis is a parasitic infection prevalent in many areas. The parasitic agent is usually transmitted by Phlebotomous sp. Lip leishmaniasis is a type of cutaneous leishmaniasis, which has rarely been reported. In a retrospective study performed in Ahwaz, center of Khuzestan province, southwest ...
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Cutaneous leishmaniasis is a parasitic infection prevalent in many areas. The parasitic agent is usually transmitted by Phlebotomous sp. Lip leishmaniasis is a type of cutaneous leishmaniasis, which has rarely been reported. In a retrospective study performed in Ahwaz, center of Khuzestan province, southwest of Iran, 2861 patients were detected during 1986-1996. Seventeen of these patients (0.59%) had lower or upper lip leishmaniasis. The patients, age ranged from 3 months to 40 years. Duration of infection was 2 to 4 months. Eleven patients had only lip lesions whereas 6 patients had one or more skin lesions elsewhere. The appearance of lesions differed from nodules to crusted ulcers, usually observed on the vermilion border. Most of the cases failed to respond to topical or systemic antibiotic therapy. The diagnosis was based on the demonstration of Leishman bodies in Giemsa stained smears.