Anchitha H; Pramod Kumar; Deepti Dsouza; Pooja K Suresh
Abstract
Tufted angioma is an uncommon vascular benign tumor of infancy or early childhood with slow and indolent growth. We report the case of a four-year-old boy with an asymptomatic annular lesion over the nape of the neck resembling granuloma annulare. Punch biopsy revealed multiple scattered vascular lobules ...
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Tufted angioma is an uncommon vascular benign tumor of infancy or early childhood with slow and indolent growth. We report the case of a four-year-old boy with an asymptomatic annular lesion over the nape of the neck resembling granuloma annulare. Punch biopsy revealed multiple scattered vascular lobules or tufts. Aggregates of closely packed, dilated to compressed vascular spaces with plump endothelial cell lining were seen in the dermis, confirming the diagnosis of tufted angioma. Immunohistochemical positivity was present with CD31 and CD34 staining of endothelial cells. It is a slow-growing tumor; Kasabach–Merritt syndrome (KMS) and consumptive coagulopathy are rare complications. Blood coagulation profiles were within normal limits. In our case, the lack of reliable distinguishing characteristics of the vascular tumor and atypical annular presentation was a source of diagnostic confusion. Tenderness, typically present in tufted angiomas, was absent in our patient. This unusual case illustrates that clinicians should recognize an annular configuration as an atypical manifestation of tufted angioma.
Banihashemi Mahnaz; Mohammad Javad Yazdanpanah; Soleiman Nouri; Sarah Hashemzadeh
Volume 19, Issue 4 , 2016, , Pages 136-138
Abstract
The association of granuloma annulare and some neoplasms is controversial. However, there is an increase in the number of case reports and relevant studies supporting the conceptof granuloma annulare being associated with certain types of hematologic neoplasms and solid tumors.Herein, we describe a 54-year-old ...
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The association of granuloma annulare and some neoplasms is controversial. However, there is an increase in the number of case reports and relevant studies supporting the conceptof granuloma annulare being associated with certain types of hematologic neoplasms and solid tumors.Herein, we describe a 54-year-old woman with a 20-month history of generalized annular lesions that did not respond to conventional treatment and was followed by breast cancer. Only two cases of granuloma annulare and breast cancer have been reported so far in the literature. We believe that these cases emphasize on considering granuloma annulare as a possible paraneoplastic dermatoses.
Hamideh Herizchi Qadim; Shahla Talgini; Mohammad Reza Ranjkesh; Neda Yousefi
Volume 11, Issue 3 , 2008, , Pages 123-125
Abstract
Granuloma annulare is one of the granulomatous dermatoses, the localized form of which is the most common clinical type, although rare variants such as subcutaneous form have been reported.We present a 22-year-old girl with asymptomatic cutaneous lesions on her fingers from 14 years ago.On physical examination, ...
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Granuloma annulare is one of the granulomatous dermatoses, the localized form of which is the most common clinical type, although rare variants such as subcutaneous form have been reported.We present a 22-year-old girl with asymptomatic cutaneous lesions on her fingers from 14 years ago.On physical examination, multiple nodules with rubbery consistency were noted on palmar aspects of fingers of both hands.Histopathologic examination showed granulomas with a palisading pattern and degeneration of collagen bundles. The diagnosis of subcutaneous granuloma annulare was confirmed. Intralesional triamcinolone prescribed for the patient caused slight improvement.
Farhad Malekzad; Behrooz Barikbin; Zahra Ghoorchiani
Volume 10, Issue 1 , 2007, , Pages 78-82
Abstract
Perforating granuloma annulare (PGA) is a rare subtype of GA. It is characterized by crops of erythematous umblicated or scaly papules. Plaques, pustule-like lesions and scars may also be seen. It can be localized or generalized.Transepithelial elimination of mucinous, degenerating collagen fibers and ...
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Perforating granuloma annulare (PGA) is a rare subtype of GA. It is characterized by crops of erythematous umblicated or scaly papules. Plaques, pustule-like lesions and scars may also be seen. It can be localized or generalized.Transepithelial elimination of mucinous, degenerating collagen fibers and surrounding palisading lymphohistiocytic granulomas, are important histologic features.The patient reported here was a 23-year-old man with recurrent crops (every few weeks) of umbilicated papular lesions predominantly affecting trunk and extremities for 8 years, which resolved with varioliform scars.
I Esfandiar Pour; F Darvish Damavandi; F Fahimi
Volume 7, Issue 3 , 2004, , Pages 185-191
Abstract
Generalized granuloma (GA) is an inflammatory benign cutaneous disease of unknown etiology that may manifest different clinical features. The most common presentation or classic form of the disease is flesh colored, annular, grouped papules. They usually are on the extremities especially on the lateral ...
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Generalized granuloma (GA) is an inflammatory benign cutaneous disease of unknown etiology that may manifest different clinical features. The most common presentation or classic form of the disease is flesh colored, annular, grouped papules. They usually are on the extremities especially on the lateral or dorsal surfaces of the fingers, hands, wrists, ankles, and insteps. Several clinical manifestations have been reported for this disease. Variants, such as localized, generalized, subcutaneous, linear, perforating and patch GA, have been reported. The generalized form may present as either disseminated, individual, usually skin-colored papules arise anywhere on the skin surface especially trunk, or annular to circinate erythematous lesions that resemble erythema multiform, erythema migrans, erythema annulare centrifugum and erythema gyratum repens. In latter group, the popular quality is less obvious than the erythema. In these lesions, rings may spread centrifugally and central hyper pigmentation may be present. This report describes a case of generalized GA in a 46-year-old diabetic woman with annular and circinate erythematous plaques resembling erythema annulare. At first according to clinical and histological findings, diagnosis of erythema gyratum repens had been suggested but later, GA was confirmed.
