Narges Alizadeh; Javad Golchai; Atefeh Ghanbari; Behrooz Golchai; Shirin Zaresharifi
Abstract
Background: Anogenital warts are the most prevalent sexually transmitted disease worldwide and are caused by human papillomavirus (HPV). There are more than 100 different types of HPV, of which certain types make the patient more susceptible to malignant neoplasms. This study aimed to determine the frequencies ...
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Background: Anogenital warts are the most prevalent sexually transmitted disease worldwide and are caused by human papillomavirus (HPV). There are more than 100 different types of HPV, of which certain types make the patient more susceptible to malignant neoplasms. This study aimed to determine the frequencies of specific types of HPV in anogenital warts.
Methods: This study included 157 patients diagnosed with anogenital warts that underwent HPV DNA detection using polymerase chain reaction (PCR) with INNO-LiPA genotyping assay.
Results: Of 157 patients with anogenital warts, 122 samples (77.7%) were positive for HPV, with some patients showing mixed HPV subtypes. HPV 6 (n = 99; 68.3%) and HPV 11 (n = 13; 8.9%) were the most prevalent types. 101 patients were male (64.3%). The mean age was 32.02 ± 10.06 years (range: 2 to 72 years). Most patients were infected with the low-risk types (80%); the high-risk HPV type 16 was significantly more common among women (P = 0.0001).
Conclusion: This study showed the higher relative frequency of HPV6 and HPV11 in anogenital warts in Guilan, northern Iran. The frequency of genital HPV infection appears to be higher among men, but the frequency of high-risk types seems to be higher among women.
Azadeh Goodarzi; Mahsa Farshidzadeh; Masoumeh Roohaninasab; Najmolsadat Atefi; Elham Behrangi
Abstract
Background: The use of vitamin D and its analogues in the treatment of warts has been to be effective and painless without any considerable side effects, unlike some other routine safe and effective therapeutic modalities such as cryotherapy that in some cases is really difficult ...
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Background: The use of vitamin D and its analogues in the treatment of warts has been to be effective and painless without any considerable side effects, unlike some other routine safe and effective therapeutic modalities such as cryotherapy that in some cases is really difficult to perform due to related pain, especially in the children. Owing to a probable relationship between the deficiency of serum vitamin D and warts, this research aimed to find the association between level of serum vitamin D and warts. Methods: This case-control study was conducted on 56 subjects in Rasoul Akram Hospital, Tehran, Iran, for 18 months. The subjects were randomly divided into case and control groups, including 28 age and sex-matched subjects in each of them. The required data were extracted through a questionnaire. Finally, the data were analyzed in the SPSS software V.22 using tests such as Mann-Whitney and Pearson correlation. Results: In this study, 56 people were examined, and 28 subjects were included in both case and control groups. The mean serum level of vitamin D in both case and control groups was 23.564and 31.593, respectively. The association between serum levels of vitamin D in the group with and without wart was not significant in both men and female groups. Serum vitamin D levels were compared in two groups of under 18 years old and between 18 and 50 years old, which were not statistically significant. Conclusion: According to our results, there is no significant relationship between serum vitamin D levels and existence of warts. This relationship is not statistically significant at the level of age and sex variables, and there is no difference in age and gender between the case and control groups.
Gholamreza Eshghi; Leila Khezrian; Alireza Ghasemi-Basir; Heshmat-allah Babaee-Kiadehi
Volume 17, Issue 2 , 2014, , Pages 76-78
Abstract
Focal epithelial hyperplasia or Heck’s disease is a benign, rare viral disease of the oral cavity and is associated with human papillomavirus 13 and 32 (HPV-13 and HPV-32). Most patients are children but adults may also be at risk. Clinically, the patients have multiple small white or pink papules ...
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Focal epithelial hyperplasia or Heck’s disease is a benign, rare viral disease of the oral cavity and is associated with human papillomavirus 13 and 32 (HPV-13 and HPV-32). Most patients are children but adults may also be at risk. Clinically, the patients have multiple small white or pink papules on the mucosal surface of the lips, buccal mucosa and the tongue. In Iran, this disease seems to be rare. Herein, we describe an adult Iranian case of focal epithelial hyperplasia.
