Rohit Singla; Kritika Singla; Saurabh Swaroop Gupta; Sanjeev Gupta; Aneet Mahendra; Akriti Gakhar
Abstract
Background: Multiple studies indicate the correlation between lichen planus (LP) and certain systemic disorders. Data suggest an increased incidence of dyslipidemia with LP. Abnormal lipid levels are major risk factors for developing atherosclerotic changes and cardiovascular disorders (CVD). Non-high-density ...
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Background: Multiple studies indicate the correlation between lichen planus (LP) and certain systemic disorders. Data suggest an increased incidence of dyslipidemia with LP. Abnormal lipid levels are major risk factors for developing atherosclerotic changes and cardiovascular disorders (CVD). Non-high-density lipoprotein cholesterol (non-HDL-C) is a reliable marker for cardiovascular events. If non-HDL-C levels are raised in LP patients, it would mean that these individuals are high-risk patients and should be investigated periodically. We aimed to find non-HDL-C serum levels in cases of lichen planus and compare them with controls.Methods: We compared lipid profiles between 100 cases of LP and 50 healthy controls.Results: Non-HDL-C levels were significantly higher in cases than controls (P = 0.002). The non-HDL-C level was elevated in 67% of LP cases, compared to 42% of controls.Conclusions: We demonstrated higher levels of non-HDL-C in LP patients than in controls, confirming the increased risk of CVDs in LP patients.
Mohammad Ebrahimzadeh; Ali Pedarzadeh; Farideh Dehghani; Mohammad Moslemzadeh
Volume 19, Issue 1 , 2016, , Pages 6-10
Abstract
Background: Worldwide, coronary heart disease is the most important cause of mortality and morbidity. Although numerous studies have documented the relationship between male pattern baldness and cardiovascular disease (CVD), few studies focused on this association in women. This study intended to evaluate ...
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Background: Worldwide, coronary heart disease is the most important cause of mortality and morbidity. Although numerous studies have documented the relationship between male pattern baldness and cardiovascular disease (CVD), few studies focused on this association in women. This study intended to evaluate the relationship between coronary artery disease and androgenetic alopecia (AGA) in both men and women.Methods: This case-control study included 200 people, 100 (50 men and 50 women) with coronary heart disease (CHD) and 100 healthy control subjects (50 men and 50 women). Both groups were assessed for grading the severity of their baldness. The collected data were analyzed by the chi-square test.Results: A total of 74% of participants in this group had hair loss severity of grades IV-VIII, however in the control group, 50% had remarkable hair loss. There was a significant association between coronary artery disease and hair loss grade IV onward in men (P=0.038) but this relationship was not observed in women.Conclusion: Male patients with AGA are at greater risk for developing CVD.