Zahra Akbari; Mohammad Shafie'ei; Nastaran Sarvipour; Mohadese Ahmadzade; Hamidreza Rouientan; Saeedeh Farajzadeh; Najmeh Ahramiyanpour
Abstract
Background: Among many coronavirus disease 2019 (COVID-19)integumentary system involvements, alopecia is one of the leastinvestigated. This disorder has been reported in many individualswho have suffered from varying severities of COVID-19. Weaimed to systematically review studies evaluating the onset ...
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Background: Among many coronavirus disease 2019 (COVID-19)integumentary system involvements, alopecia is one of the leastinvestigated. This disorder has been reported in many individualswho have suffered from varying severities of COVID-19. Weaimed to systematically review studies evaluating the onset ofdifferent types of alopecia following COVID-19.Methods: The PubMed, Scopus, Web of Science, and Embasedatabases were searched with a specified string of relevantkeywords. After quality assessments, the data of eligible studieswere qualitatively and quantitatively synthesized.Results: Sixteen studies were included in our review, six ofwhich underwent meta-analysis for the differences in the risk ofalopecia between males and females. Though the disorder wasnot differentiated in all the cases, we found that COVID-19 wasassociated with several different types of alopecia, includingtelogen effluvium, alopecia areata, alopecia parvimaculata, andlichen planopilaris. Moreover, although statistically insignificant,the odds of developing alopecia favored the female population.Conclusion: Although many hypotheses have been suggested asto why an individual might be more predisposed to developingalopecia following COVID-19, the data obtained from the studiesyielded results that could not lead to definite conclusions. Therefore,we recommend that further studies be conducted to evaluatethe association between the two phenomena more confidently.
Prodip Sarkar; Karunamoy Chakraborti; Sudeshna Mondal; Loknath Ghoshal; Debabrata Bandyopadhyay
Abstract
Background: Androgenetic alopecia is defined as patterned hair loss caused by androgens in genetically susceptible individuals. Metabolic syndrome is a cluster of interrelated risk factors that increase the risk of coronary artery disease. Androgenetic alopecia is associated with metabolic syndrome components ...
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Background: Androgenetic alopecia is defined as patterned hair loss caused by androgens in genetically susceptible individuals. Metabolic syndrome is a cluster of interrelated risk factors that increase the risk of coronary artery disease. Androgenetic alopecia is associated with metabolic syndrome components including insulin resistance, dyslipidemia, and obesity. This study aimed to compare the prevalence of metabolic syndrome in androgenetic alopecia patients with controls.Methods: The study groups consisted of 50 androgenetic alopecia patients and 50 controls who agreed to participate. Following recruitment into the study, history taking, clinical examination, and laboratory investigations were carried out, and details of each individual were recorded into a pre-structured case record sheet.Results: The groups were not statistically different in terms of age or sex distribution, height and weight, glucose levels, thyroid hormone level, blood counts, and lipid levels. We found that 26% of patients in the case group and 6% in the control group satisfied the definition of metabolic syndrome; this difference was significant (P = 0.007). We observed a statistically significant difference in LDL and HDL levels between the cases and controls (P = 0.0027 and 0.0091, respectively).Conclusion: Patients with androgenetic alopecia have an increased likelihood of having metabolic syndrome and must be routinely screened for hypertension, diabetes mellitus, and dyslipidemia. They should be made conscious of the more serious implications of the apparently cosmetic disorder.
Kambiz Kamyab Hesari; AliReza Ghanadan; Vahidehsadat Azhari; Shirin Taraz Jamshidi; Reza Amiri; Hamidreza Mahmoudi; Ali Salehi Farid; Ali Nili; Anahita Borzouei; Maryam Daneshpazhooh
Abstract
Background: Lichen planopilaris (LPP) is the most common form of immune-mediated scarring alopecia. We evaluated the histopathologic features of LPP in vertical sections of scalp biopsies and compared findings between the scarring and nonscarring phases of the disease.Methods: From June 2019 to June ...
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Background: Lichen planopilaris (LPP) is the most common form of immune-mediated scarring alopecia. We evaluated the histopathologic features of LPP in vertical sections of scalp biopsies and compared findings between the scarring and nonscarring phases of the disease.Methods: From June 2019 to June 2020, vertically sectioned scalp biopsies of 70 new cases of LPP were examined (H&E) according to North American Hair Research Society criteria. Furthermore, patients were divided into two groups based on either the presence or the absence of vertical fibrous bands, and other histopathological features were compared between these two groups.Results: Characteristic findings of LPP were perifollicular lymphocytic infiltration (97.1%), follicular interface degeneration (60%), and perifollicular plasmacytic infiltration (21.4%). Vacuolar degeneration in the dermo-epidermal junction (38.6%), perifollicular lamellar fibroplasia (67.1%), loss of sebaceous glands (87.1%), perifollicular cleft formation (28.6%), and vertical fibrous tracts (65.7%) were also found. Furthermore, we found a significant correlation between the presence of fibrous tracts with both loss of sebaceous glands (P = 0.005) and the presence of lamellar fibroplasia (P = 0.015).Conclusion: The most common findings in the histopathological examination of LPP slides are perifollicular lymphocytic infiltration and loss of the sebaceous glands. Furthermore, sebaceous gland loss and perifollicular lamellar fibroplasia correlate with the scarring phase of LPP.
Mohammad Ebrahimzadeh-Ardakani; Kazem Ansari; Hesan Pourgholamali; Zahra Sadri
Abstract
Background: Postpartum hair loss is one of the most common childbirth complications, sharing an association with certain clinical and disease-related factors. The aim of this study was to determine the frequency of postpartum hair loss and risk factors in women referring to Yazd primary healthcare clinics.Methods: ...
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Background: Postpartum hair loss is one of the most common childbirth complications, sharing an association with certain clinical and disease-related factors. The aim of this study was to determine the frequency of postpartum hair loss and risk factors in women referring to Yazd primary healthcare clinics.Methods: This descriptive cross-sectional study was conducted in 2016 in four dermatology clinics in Yazd, Iran. The statistical population included all women aged 17 to 48 years who had given birth during the previous six months and attended primary healthcare clinics. Cluster sampling was performed to select the participants; 329 women visiting four clinics in Yazd were examined for hair loss and its risk factors. Study data were analyzed using SPSS software (t-test, ANOVA, and chi-squared test).Results: The mean age of the participants was 29.29 ± 6.12 years. In this study, 68.4% of participants had postpartum hair loss. There was a statistically significant relationship between postpartum hair loss and variables such as anemia (P = 0.001), breastfeeding (P = 0.002), nocturnal feeding (P = 0.001), gestational diabetes (P = 0.019), history of hypothyroidism (P = 0.001), and stress before and during delivery (P = 0.001 for both).Conclusions: This study revealed that a history of hair loss, breastfeeding, gestational diabetes, and stress could affect postpartum hair loss. Therefore, these factors might be used as hair loss predictors in women undergoing pregnancy.
Hamed Zartab; Behzad Iranmanesh; Rezvan Amiri; Simin Shamsi Meymandi
Abstract
Background: Alopecic and aseptic nodule of the scalp (AANS) is a rare entity characterized by the presence of sterile, culturenegative nodules/cysts and areas of non-scarring alopecia.Methods: We describe a case on the vertex of a 26-year-old man with a two-week history of a nodular, moderately-fluctuant, ...
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Background: Alopecic and aseptic nodule of the scalp (AANS) is a rare entity characterized by the presence of sterile, culturenegative nodules/cysts and areas of non-scarring alopecia.Methods: We describe a case on the vertex of a 26-year-old man with a two-week history of a nodular, moderately-fluctuant, alopecic lesion. The patient also had cutis verticis gyrata (CVG).Results: The aspirate culture was negative and histopathologic findings were nonspecific. We also performed a trichoscopy of the lesion. After eight weeks, the patient showed dramatic clinical response to doxycycline and a dose of intralesional corticosteroid.Conclusion: This is the first report of the simultaneous occurrence of AANS and primary essential CVG. AANS is a probably under-reported cause of non-scarring alopecia with a rapid and dramatic response to non-surgical treatment and a generally good prognosis.
Leili Amani; Fatemeh Fadaei; Mohammadreza Shams Ardakani; Mehran Mirabzadeh Ardakani; Seyede Nargess Sadati Lamardi; Laila Shirbeigi
Abstract
Background: Skin conditions are among the most common health problems worldwide and are associated with immense psychological, social, and financial burdens. Atopic dermatitis, alopecia, eczema, diabetic ulcers, and abscesses are common acute or chronic conditions, which are increasing ...
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Background: Skin conditions are among the most common health problems worldwide and are associated with immense psychological, social, and financial burdens. Atopic dermatitis, alopecia, eczema, diabetic ulcers, and abscesses are common acute or chronic conditions, which are increasing dramatically in prevalence due to industrialization and unhealthy lifestyle habits. The use of complementary and alternative medicine to treat skin diseases has been increasing in recent years. Methods: This review focuses on proposed skin conditions for leech therapy as mentioned by Avicenna, a great Iranian philosopher and physician (980-1037 AD)in the Canon of Medicine. Electronic databases including PubMed, Scopus, and Google Scholar were searched for clinical studies on treatment protocols in this book to compare them with recent clinical trials involving leech therapy. Results: Investigation of traditional Iranian medicine literature can lead to the identification of natural medicines for the management of skin problems. Leech saliva contains anti-coagulative, antiaggregative, and vasodilatory components. Conclusions: In addition to the annelid’s mechanical ability to extract blood, leeches can contribute to patients’ health while posing minimal risks.
Ahmad Reza Taheri; Mozhgan Afkhamizadeh; Sara Sabourirad; Omid Hassani; Somaye Ghanizadeh
Abstract
Background: Androgenetic alopecia (AGA) is the most prevailing type of progressive hair loss. Thus far, some previous studies have investigated the correlation between AGA and metabolicsyndrome (MetS). However, due to the inconsistency of their results, our study aims at evaluating the ...
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Background: Androgenetic alopecia (AGA) is the most prevailing type of progressive hair loss. Thus far, some previous studies have investigated the correlation between AGA and metabolicsyndrome (MetS). However, due to the inconsistency of their results, our study aims at evaluating the association between AGA and MetS.Methods: Fifty two male patients with grade III-V AGA, based on Ebling’s scale, and 50 control subjects were enrolled in the present study. All participants were evaluated for the presenceof Mets based on the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III).Results: The prevalence of MetS was 51.3% in AGA group and 17.8% in control group (P=0.003). Among MetS parameters, Systolic blood pressure (P=0.003) and waist circumference (P<0.001)were statistically significant in AGA patients compared to the control group.Conclusion: Our study demonstrated that the association between AGA and MetS is of great importance. Therefore, early detection can be beneficial for early intervention to lower the incidence of MetS and further complications.
Namazi Nastaran; Golfeshan Atefe; Saghi Bita
Volume 19, Issue 2 , 2016, , Pages 57-59
Abstract
Gyrate atrophy (GA) is a rare, progressive metabolic choroid and retinal degeneration that results from a deficiency of the pyridoxal phosphate-dependent mitochondrial matrix enzyme ornithine aminotransferase. Here, we report the case of a 40-yearold woman who presented with a gradual decline in visual ...
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Gyrate atrophy (GA) is a rare, progressive metabolic choroid and retinal degeneration that results from a deficiency of the pyridoxal phosphate-dependent mitochondrial matrix enzyme ornithine aminotransferase. Here, we report the case of a 40-yearold woman who presented with a gradual decline in visual acuity since puberty, along with a history of high myopia and cataract surgery. She was admitted to the Dermatology Clinic with chief complaints of sparse hair on her scalp, eyelids, eyebrows and other areas of the body for the previous 5 years. Physical examination showed that scalp hair along with hair from other parts of her body were fine, straight, and sparse with areas of non-well defined alopecia. Hyperornithinemia was documented during laboratory evaluation of the patient.
Shabanzadeh-Dehkordi Hossein; Kamkhah Amir Farhad
Volume 12, Issue 1 , 2009, , Pages 26-30
Abstract
Lipedematous scalp (LS) and Lipedematous Alopecia (LA) are uncommon disorders of unknown etiology, pathogenesis and treatment. They are characterized by thickening of the subcutaneous layer of the scalp and a boggy scalp on palpation. Also, hair loss or shortening of hair is seen in LA. In this report, ...
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Lipedematous scalp (LS) and Lipedematous Alopecia (LA) are uncommon disorders of unknown etiology, pathogenesis and treatment. They are characterized by thickening of the subcutaneous layer of the scalp and a boggy scalp on palpation. Also, hair loss or shortening of hair is seen in LA. In this report, we describe LS in a 42-year-old woman presented with a diffuse thickened and spongy scalp. To date, only 10 cases of LS and 18 cases of LA have been reported and we report the 11th case of LS but it seems to be more prevalent than reported.
MR Mortazavi
Volume 7, Issue 1 , 2003, , Pages 46-50
Abstract
Localized scalp hair loss has different causes which alopecia areata, trichotillomania, tinea capitis and early lupus erythematosus are the most important ones. There are several reports of localized alopecia after tick and flea bites and bee stings, but there is only one report of ant-induced alopecia ...
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Localized scalp hair loss has different causes which alopecia areata, trichotillomania, tinea capitis and early lupus erythematosus are the most important ones. There are several reports of localized alopecia after tick and flea bites and bee stings, but there is only one report of ant-induced alopecia in the literature. We report herein two cases of alopecia induced by ants of genus Pheidole (Species pallidula).
