Karen Christelle; Maryam Mohd Zulkifli; Nani Draman
Abstract
Pemphigoid gestationis is an unusual autoimmune dermatosis of pregnancy, and recurrences may occur in consequent pregnancies. This dermatosis begins with intense itching, which progresses to papules and annular plaques and, consequently, vesicles and tense bullae. These lesions typically arise from the ...
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Pemphigoid gestationis is an unusual autoimmune dermatosis of pregnancy, and recurrences may occur in consequent pregnancies. This dermatosis begins with intense itching, which progresses to papules and annular plaques and, consequently, vesicles and tense bullae. These lesions typically arise from the umbilical region then spread centrifugally to the abdomen, thighs, palms, and soles. Diagnosis is based on clinical examination and immunohistopathologic studies. Here, we report the case of a 29-year-old women who developed recurrent pemphigoid gestationis in her second pregnancy and the postpartum period in 2020. The condition initially manifested during her first pregnancy in 2014. She was successfully treated with oral prednisolone and the local application of betamethasone cream. Pruritic skin lesions are a common complaint among pregnant women. Clinicians should be aware of autoimmune dermatosis of pregnancy, its fetomaternal and neonatal complications, and its possibility of recurrence in subsequent pregnancies.
S Nasiri; F Mollayi; M Vasheghani Farahani
Volume 3, Issue 4 , 2000, , Pages 34-37
Abstract
Background: Most of patients with bullous pemphigoid are at old age and its differentiation from other bullous diseases is important. There is no report of it in Iran. Objective: This study was done in order to determine clinical and paraclinical features, natural course and response to treatment in ...
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Background: Most of patients with bullous pemphigoid are at old age and its differentiation from other bullous diseases is important. There is no report of it in Iran. Objective: This study was done in order to determine clinical and paraclinical features, natural course and response to treatment in patients with bullous pemphigoid admitted in Loghman Hakim Hospital in 1992-1997. Patients and Methods: This descriptive study was done retrospectively by reviewing the existing files of 17 bullous pemphigoid patients admitted in the skin diseases ward of Loghman Hakim Hospital in Tehran in 1992-1997. The diagnosis was confirmed by histopathological examination in all of the patients. Results: The age range of the patients was 19-80 years; most of them were in the 6th-8th decades. 58.8% of the patients were female. Initial lesions were bullous in 53%, eczematous in 29.4% and erythematous or urticarial in 17.6%. 53% of patients were complaining of pruritus. Mucosal involvement was seen in 47%, all in the oral mucosa; only in one of the patients genital area was also involved. No malignancy was seen. 52% of the patients responded to oral prednisolone alone. None of the patients died from the disease. Conclusion: Iranian bullous pemphigoid patients show similar epidemiologic and clinical features to other parts of world.
