Maryam Nasimi; Robabeh Abedini; Zahra Halaji; Maryam Hosseinizadeh; Fariba Mohammadi
Abstract
Background: Basal cell carcinoma (BCC) is the most common form of malignancy in white populations. It has been hypothesized that dietary factors may play a role in BCC development. In this study, serum levels of folic acid and vitamin B12 were evaluated in patients with BCC to investigate the potential ...
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Background: Basal cell carcinoma (BCC) is the most common form of malignancy in white populations. It has been hypothesized that dietary factors may play a role in BCC development. In this study, serum levels of folic acid and vitamin B12 were evaluated in patients with BCC to investigate the potential role of these vitamins in BCC development.Methods: Forty-five BCC patients and 45 age- and sex-matched healthy controls were enrolled in the study. Patients with a history of radiotherapy in the affected area were excluded. All participants completed a questionnaire including demographic characteristics, and blood samples were taken to evaluate serum levels of folic acid and vitamin B12.Results: There were no significant differences in serum levels of vitamin B12 and folic acid between healthy controls and BCC patients. Serum levels of vitamin B12 were significantly higher in female patients than male patients.Conclusion: It seems that BCC is not related to serum levels of vitamin B12 and folic acid; however, this issue should be studied with larger sample sizes.
Ghiasi Maryam; Lajevardi Vahide; Farahbakhsh Abbas
Volume 18, Issue 2 , 2015, , Pages 45-50
Abstract
Background and Aim: Vitiligo is a hypopigmentation disorder of the skin that is associated with depression and an impaired quality of life. There has been conflicting reports on the association between the disease and the serum levels of homocysteine, vitamin B12, and folic acid.In this study,serum levels ...
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Background and Aim: Vitiligo is a hypopigmentation disorder of the skin that is associated with depression and an impaired quality of life. There has been conflicting reports on the association between the disease and the serum levels of homocysteine, vitamin B12, and folic acid.In this study,serum levels of homocysteine, vitamin B12, and folic acid were evaluated in patients with vitiligo.Methods: Thirty patients with vitiligo and 30 age- and sex-matched healthy controls were recruited. Venous blood samples wereobtained from the study subjects and the levels of homocysteine, vitamin B12, and folic acid were measured. Data were analyzedusing non-parametric statistical tests.Results: No significant differences were found in the levels of serum homocysteine, vitamin B12, and folic acid between vitiligo patients and healthy controls. Moreover, there were no associations between these factors and age, body weight, gender,as well as the extent, duration, and type of vitiligo.Conclusion: It seems that vitiligo is not related to serum levels of homocysteine, vitamin B12, and folic acid.