Behrooz Barikbin; Afsaneh Maarefat; Rayhaneh Rahgoshai; Hamideh Moravvej; Nahid Mohtasham; Maryam Yousefi
Volume 13, Issue 4 , 2010, , Pages 131-134
Abstract
Background: Hand eczema is one of the most common dermatologic diseases requiring treatment but common therapeutics such as corticosteroids and anti-histamines have numerous side effects. So, use of herbal agents, which generally have no major side effects, may be useful especially if their efficacy ...
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Background: Hand eczema is one of the most common dermatologic diseases requiring treatment but common therapeutics such as corticosteroids and anti-histamines have numerous side effects. So, use of herbal agents, which generally have no major side effects, may be useful especially if their efficacy is established. Malva Sylvestris (MS) is a tropical plant in Iran with cooling characteristics. Hence, in this study, its efficacy in of the treatment of hand eczema was evaluated. Methods: In this randomized clinical trial, 50 patients with hand eczema who were visited at Shohada-e Tajrish and Loghman hospitals, Tehran, Iran, between 2006 and 2008, were recruited and divided into two groups. In the first group, MS 4% ointment was applied twice a day and in the other group, placebo ointment was usd. The efficacy and side effects were evaluated three and six weeks after beginning of the treatment. Results: Mean age of the patients was 37.3 years and 35.6 years in MS and placebo groups, respectively (P > 0.05). There were no therapeutic adverse effects in the groups. There was a statistically significant difference in all measured scores between two groups in the first and second follow-up sessions (P < 0.0001). Conclusion: Malva Sylvestris seems to be a safe and effective therapeutic modality for the treatment of hand eczema and can be used as an optimal substitute for corticosteroids and antihistamines.
M Emam Ghoreishi; R Salman Pour; MR Panjeh Shahin
Volume 8, Issue 3 , 2005, , Pages 218-223
Abstract
Background: Hirsutism can result in cosmetic and psychological problems in women. Because of diverse etiological factors, treatment with a single drug is not usually successful. On the other hand, treatment of Hirsutism can be associated with adverse effects. Objective: To evaluate the efficacy of a ...
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Background: Hirsutism can result in cosmetic and psychological problems in women. Because of diverse etiological factors, treatment with a single drug is not usually successful. On the other hand, treatment of Hirsutism can be associated with adverse effects. Objective: To evaluate the efficacy of a herbal ointment consisted of leguminosea spp. and zingiberaceae spp. extracts in reduction of hair density in hirsute women. Patients and Methods: In an open clinical trial 10 hirsute women were treated with a herbal ointment 3 times a day for 2 weeks in 3 consecutive months. Pre and post-treatment assessment of number, length, and diameter of hairs were done in individual patients. Paired T-test was used for statistical analyses. Results: After 3 treatment courses the mean number of the hairs showed significant reduction in comparison with pre-treatment values. Some patients mentioned that treatment resulted in softer, thinner and lighter hairs. Conclusion: The studied herbal ointment was effective in hair density reduction in hirsute patients. It was also a simple, inexpensive and safe treatment for Hirsutism.