Narges Alizadeh; Javad Golchai; Atefeh Ghanbari; Behrooz Golchai; Shirin Zaresharifi
Abstract
Background: Anogenital warts are the most prevalent sexually transmitted disease worldwide and are caused by human papillomavirus (HPV). There are more than 100 different types of HPV, of which certain types make the patient more susceptible to malignant neoplasms. This study aimed to determine the frequencies ...
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Background: Anogenital warts are the most prevalent sexually transmitted disease worldwide and are caused by human papillomavirus (HPV). There are more than 100 different types of HPV, of which certain types make the patient more susceptible to malignant neoplasms. This study aimed to determine the frequencies of specific types of HPV in anogenital warts.
Methods: This study included 157 patients diagnosed with anogenital warts that underwent HPV DNA detection using polymerase chain reaction (PCR) with INNO-LiPA genotyping assay.
Results: Of 157 patients with anogenital warts, 122 samples (77.7%) were positive for HPV, with some patients showing mixed HPV subtypes. HPV 6 (n = 99; 68.3%) and HPV 11 (n = 13; 8.9%) were the most prevalent types. 101 patients were male (64.3%). The mean age was 32.02 ± 10.06 years (range: 2 to 72 years). Most patients were infected with the low-risk types (80%); the high-risk HPV type 16 was significantly more common among women (P = 0.0001).
Conclusion: This study showed the higher relative frequency of HPV6 and HPV11 in anogenital warts in Guilan, northern Iran. The frequency of genital HPV infection appears to be higher among men, but the frequency of high-risk types seems to be higher among women.
Tabari Soudabeh Tirgar; Barat Shahnaz; Shakerian Mohammad Ali; Hashemi Kamal; Saeedi Fayyaz
Volume 19, Issue 3 , 2016, , Pages 89-92
Abstract
Background: Genital warts are one of the most common viral sexually transmitted diseases in the world. They are caused by different human papilloma viruses and lesions may have benign to malignant transformation. The main purpose of this study was to determine the prevalence of condyloma acuminata in ...
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Background: Genital warts are one of the most common viral sexually transmitted diseases in the world. They are caused by different human papilloma viruses and lesions may have benign to malignant transformation. The main purpose of this study was to determine the prevalence of condyloma acuminata in the spouses of patients with genital warts. Methods: This cross-sectional study was done on 153 patients with genital warts and their spouses who were referred to dermatology and gynecology clinics of Babol University of Medical Science (North of Iran) between 2009 and 2012. All cases were clinically examined by dermatologists and gynecologists. After obtaining consent, the data including patients’ sex and age, genital wart in the spouse, history of warts in other sites of the body, positive family history of all forms of warts, smoking, addiction, alcohol consumption, and OCP use were collected via a questionnaire and analyzed with t and chi-square tests. P values less than 0.05 were considered significant. Results: In this study, 100 (65.4%) patients were women and 53 (34.6%) were men. Genital warts were detected in 25.5% of the spouses. The mean age of the patients and their spouses was 30.2±8.7 and 31.5 ±7.4 years, respectively. There was no significant correlation between age and genital wart in the spouse. Conclusion: The results showed that genital warts are a relatively highly infectious disease. Our recommendation for prevention of genital warts is education and clinical examination of the patients’ spouses.