Jaspriya Sandhu; Sunil Kumar Gupta; Navneet Kaur; Aditi Bansal; Bhavna Garg
Abstract
Acquired digital fibrokeratoma (ADFK) is a rare benign fibroustissue tumor that occurs over the extremities, predominantly inthe periungual area. We report a case of ADFK over the digitof the right hand presenting as a finger-like growth; the base ofthe lesion showed a collarette of scales. The lesion ...
Read More
Acquired digital fibrokeratoma (ADFK) is a rare benign fibroustissue tumor that occurs over the extremities, predominantly inthe periungual area. We report a case of ADFK over the digitof the right hand presenting as a finger-like growth; the base ofthe lesion showed a collarette of scales. The lesion was excisedwith ablative CO2 laser. The histopathology was typical, showinghyperkeratosis and acanthosis. The core of the lesion had abundantcollagen fibers perpendicular to the long axis of the epithelium.There was good healing with minimal scarring; the patient wasfollowed up, and no recurrence was reported more than oneyear later. ADFK is a relatively rare tumor, with less than 150cases reported worldwide; we present a concise review of thepublished ADFK cases with their clinical and histopathologicalcharacteristics. To the best of our knowledge, this is the seventhsuch case to be reported from India.
Khooei Alireza; Farhadi Farzaneh
Volume 10, Issue 4 , 2007, , Pages 262-270
Abstract
Background and aim: The skin has some appendages that give origin to various tumors. These tumors are generally divided to pilosebaceous and sweat glands tumors according to embryologic and histological features. Clinical and histological characteristics of these tumors are also divergent. In addition, ...
Read More
Background and aim: The skin has some appendages that give origin to various tumors. These tumors are generally divided to pilosebaceous and sweat glands tumors according to embryologic and histological features. Clinical and histological characteristics of these tumors are also divergent. In addition, classification of them according to histological background has been changed considerably in recent years. The aim of this study is to asses the frequency and clinicoepidemiologic characteristics of these tumors based on re-evaluation of the tissue specimens by applying new histological criteria for a better understanding, experience and reclassification. Materials and methods: All tissue samples with a definite, differential, probable or uncertain diagnosis of any kind of skin appendage tumors, archived in Pathology Department of Imam Reza University Hospital of Mashhad, during the past 30 years (1976-2005) were elicited. All the specimens were reobserved histopathologically by applying new diagnostic criteria and if necessary, were recut and stained with H&E and special histochemical stains. Clinical data were gathered and presented in tables and charts and analyzed statistically by SPSS software. Results: From 134748 archived specimens, 444 appendageal tumors were found of which 161 were of follicular origin composed of 119 pilomatrixoma (73.9%), 19 trichoepithelioma (11.8%), 15 inverted follicular keratoses (9.3%), 4 proliferating pilar tumor (2.5%), 2 trichoblastoma (1.2%), 1 trichofolliculoma (0.6%) and 1 trichoadenoma (0.6%), with a mean age of 28 years in 71 men and 90 women. The most prevalent location was head and neck area (57.5%) and the most common presentation was a nodule (81%), mostly single (94%). In most cases previous pathologic diagnosis was confirmed (95.2%) and clinico-epidemiologic features were in accordance with other world wide reports, although some changes in tissue diagnosis and differences in clinico-epidemiologic features were noted. Conclusion: Hair follicular tumors are relatively uncommon tumors, mostly benign and occurring in youngs specially in head and neck. Some differences in clinico-epidemiologic features could be related to race, genetic background, environment and etc. Some mistakes in previous tissue diagnosis alarm the pathologist to pay special attention to the wide range of differential diagnosis and to employ definite histopathologic criteria regarding differences in patterns of involvement.
M Omrani Fard; M Adabi; P Rajabi
Volume 4, Issue 1 , 2000, , Pages 54-57
Abstract
Neurofibroma is a tumor composed of a complex proliferation of neuromesenchymal tissue (Schwann cells, perineural cells, fibroblast, and mast cells). We report a 45-year-old female who had a slow growing, large, soft, pedunculated mass on her left lateral neck. A skin biopsy confirmed the diagnosis of ...
Read More
Neurofibroma is a tumor composed of a complex proliferation of neuromesenchymal tissue (Schwann cells, perineural cells, fibroblast, and mast cells). We report a 45-year-old female who had a slow growing, large, soft, pedunculated mass on her left lateral neck. A skin biopsy confirmed the diagnosis of neurofibroma.