Liyana D Aminuddin; Tarita Taib; Mohamad Rodi Isa; Mohan Arumugam; Sabrina A Wahab
Abstract
Background and Aim: Silicone-based products are often used to improve signs and symptoms of hypertrophic and keloid scars. An improved silicone product, ScarLess™ Hydrogel (SH), is a 5% silicone-based super-oxidized hydrogel meant to reduce keloid scars’ vascularity, elasticity, and height. ...
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Background and Aim: Silicone-based products are often used to improve signs and symptoms of hypertrophic and keloid scars. An improved silicone product, ScarLess™ Hydrogel (SH), is a 5% silicone-based super-oxidized hydrogel meant to reduce keloid scars’ vascularity, elasticity, and height. This study aimed to compare the efficacy between SH and hydrocortisone (HCT) 1% ointment in keloid treatment.Methods: This study was a prospective, single-centered, randomized, double-blind study involving twenty-eight subjects with keloid scars. The scars were assigned randomly as Scar A and Scar B in a 1:1 ratio to receive HCT or SH under occlusion, respectively, for over 12 weeks. The Patient and Observer Scar Assessment Scale (POSAS) was used for clinical evaluation.Results: According to the POSAS, there were significant improvements in both patient and observer scorings in both treatment arms.Conclusion: SH has equal therapeutic efficacy as HCT in keloid treatment. SH did not present with any safety issues or side effects.
Balighi Kamran; Jamshidi Samaneh; Daneshpajooh Maryam; Lajevardi Vahideh; Aalami Harandi Sima; Ghassemi Hamed
Volume 14, Issue 3 , 2011, , Pages 95-99
Abstract
Background: Treatment of acne scars is a therapeutic challenge that may require multiple modalities. Subcision is a procedure that has been reported to be beneficial in the treatment of acne scars. Although subcision is a valuable method, its efficacy is mild to moderate due to the high recurrence rate. ...
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Background: Treatment of acne scars is a therapeutic challenge that may require multiple modalities. Subcision is a procedure that has been reported to be beneficial in the treatment of acne scars. Although subcision is a valuable method, its efficacy is mild to moderate due to the high recurrence rate. This study aimed to evaluate the novel complementary treatment of repeated suction sessions plus subcision at the recurrence period of subcised scars. Methods: The standard technique of subcision was applied to treat scars in 12 patients; then, one side of the face underwent repeated suctioning for 2 weeks. All patients completed treatment and the follow-up period. The patients’ and investigators’ assessments of improvement were both recorded. Results: According to patients and investigators, subcision plus suction showed 81% and 65% improvement after 3 month, respectively. Subcision alone, after 3 month, was associated with 62% and 33.3% improvement according to patients and investigators, respectively. The rate of response showed a significant difference with the use of repeated suctioning. The side-effects of local edema and bruising were all transient. Conclusion: Subcision plus frequent suctioning at the recurrence period of subcision appears to be a safe technique that increases the efficacy of subcision without considerable complications.
Hajihosseini Hossein; Amini Seyed Saeed
Volume 13, Issue 3 , 2010, , Pages 103-104
Abstract
Amniotic Band Syndrome is a sporadic congenital disorder that may result in constriction bands, amputation and multiple craniofacial, visceral and body wall defects. Its incidence is estimated at approximately 1:5000 to 1:10,000 pregnancies. Band formation most frequently affects the distal segments, ...
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Amniotic Band Syndrome is a sporadic congenital disorder that may result in constriction bands, amputation and multiple craniofacial, visceral and body wall defects. Its incidence is estimated at approximately 1:5000 to 1:10,000 pregnancies. Band formation most frequently affects the distal segments, including the hand. We report a case of constriction amniotic bands involving the trunk.
Balighi Kamran; Moslehi Homayun; Robati Reza Mahmoud; Robati Amin Mahmoud
Volume 10, Issue 4 , 2007, , Pages 271-277
Abstract
Background and aim: Subcision is a procedure that has been reported to be beneficial in treatment of acne scars. The objective of this trial was to assess the efficacy of subcision in the treatment of rolling acne scars and evaluate a novel subdermal filler" absorbable plain catgut suture" with subcision. ...
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Background and aim: Subcision is a procedure that has been reported to be beneficial in treatment of acne scars. The objective of this trial was to assess the efficacy of subcision in the treatment of rolling acne scars and evaluate a novel subdermal filler" absorbable plain catgut suture" with subcision. Materials and methods: 22 patients with rolling acne scars underwent subcision, 20 of whom completed treatment and follow-up period. One side of the face underwent subcision and another side subcision with subdermal implant. The patients and investigators' assessments of improvement were both recorded. Results: Subcision showed mild improvement in about 60% of patients and moderate improvement in about 40% of them. The rate of response showed no significant difference with the use of subdermal implant. The side effects of local edema, bruising, and infection were all transient. Conclusion: Subcision appears to be a safe method to correct the rolling acne scars with long term improvement. However, the subdermal implant led to no significant superior results.
Nilforoushzadeh Afshar Mohammad Ali; Jaffari Fariba; Ansari Nazli; Moradi Shahram
Volume 10, Issue 3 , 2007, , Pages 181-186
Abstract
Background and aim: The scars of the cutaneous leishmaniasis and psychologic problems of this disease needs different intervention for its correction. Our objective in this study was to compare the efficacy of trichloroacetic acid (TCA) 50 percent solution and CO2 laser for treatment of the atrophic ...
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Background and aim: The scars of the cutaneous leishmaniasis and psychologic problems of this disease needs different intervention for its correction. Our objective in this study was to compare the efficacy of trichloroacetic acid (TCA) 50 percent solution and CO2 laser for treatment of the atrophic scars due to leishmaniasis. Materials and methods: This was a randomized clinical trial perfomed in 92 patients. Patients were randomized into 2 groups, first group were treated with TCA 50 percent solution, once monthly and for maximum of 5 months, second group were treated with CO2 laser that was performed for only one time. Patients were followed at 3 months and 6 months after starting treatment. The improvement of scar was graded by 6-point scale using digital camera and the collected data were analyzed using SPSS software and t, Wilcoxon and Mann-Whitney tests.Results: In this study that 74 females and 18 males were followed, the improvement of scar was 48.13% in the TCA group and 44.87% in the CO2 laser group. This difference was not statistically significant (P=0.55). There was also no significant difference regarding side effects between these 2 groups. Conclusion: The results of our study showed efficacy of topical treatment with 50 percent TCA solution is comparable with CO2 laser in the treatment of leishmaniasis scar. Because of the low cost and simple application of TCA solution in comparison with CO2 laser, we suggest the use of this treatment for correction of leishmaniasis or atrophic scars.
Z Nilforooshan; A Asilian; MA Nilforoosh Zadeh
Volume 8, suppl , 2004, , Pages 11-16
Abstract
Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most frequent skin cancers. The etiology of these tumors is multifactorial: Environmental and exogenous factors, genotype and phenotype factors. The development of malignant neoplasms at sites of previous dermal scars is an uncommon ...
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Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most frequent skin cancers. The etiology of these tumors is multifactorial: Environmental and exogenous factors, genotype and phenotype factors. The development of malignant neoplasms at sites of previous dermal scars is an uncommon but well recognized phenomenon, and since almost all of them were developed on exposed areas it has been hypothesized that the accompanying atrophy and decreased vascularity and adnexal structures in areas of scarring may render the affected tissues more susceptible to the effects of environmental factors, eg. ultraviolet light. We report four cases of BCC and SCC on old leishmania scars on face, and recommend that any changes on scars must be evaluated clinically and pathologically.
MH Aziz Jalali; H Ansarin; S Mirzazadeh Javaheri
Volume 7, Issue 3 , 2004, , Pages 192-194
Abstract
Basal cell carcinoma (BCC) is the most common malignant tumor of the skin, which originates from the basal cell layer of the skin. It is more common in white race with skin types I and II. Some predisposing factors are sunlight, ionizing radiation, arsenic salts, PUVA and scar. We present a case of BCC, ...
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Basal cell carcinoma (BCC) is the most common malignant tumor of the skin, which originates from the basal cell layer of the skin. It is more common in white race with skin types I and II. Some predisposing factors are sunlight, ionizing radiation, arsenic salts, PUVA and scar. We present a case of BCC, which appeared over an old scar of localized cutaneous leishmaniasis in a 49-year-old woman.
H Ansarin; A Ghahhari; SF Akbarian
Volume 6, Issue 4 , 2003, , Pages 34-45
Abstract
The available treatment modalities for hypertrophic scars and keloids have very little success. Surgical treatment of these lesions without adjuvant therapy is also associated with high recurrence rate. Hypertrophic scars and keloids are the results of a series of cellular and molecular changes which ...
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The available treatment modalities for hypertrophic scars and keloids have very little success. Surgical treatment of these lesions without adjuvant therapy is also associated with high recurrence rate. Hypertrophic scars and keloids are the results of a series of cellular and molecular changes which their identification can guide us toward new treatment modalities which may decrease the pathological factors, or help balancing the repair mechanism; thus inhibiting extensive scar formation. In this article, we have reviewed the latest treatment methods, as well as molecular and cellular reactions, which lead to the formation of hypertrophic scars and keloids.
H Ansarin; A Ghahhari; SF Akbarian
Volume 6, Issue 3 , 2003, , Pages 27-34
Abstract
The available treatment modalities for hypertrophic scars and keloids have very little success. Surgical treatment of these lesions without adjuvant therapy is also associated with high recurrence rate. Hypertrophic scars and keloids are the results of a series of cellular and molecular changes which ...
Read More
The available treatment modalities for hypertrophic scars and keloids have very little success. Surgical treatment of these lesions without adjuvant therapy is also associated with high recurrence rate. Hypertrophic scars and keloids are the results of a series of cellular and molecular changes which their identification can guide us toward new treatment modalities which may decrease the pathological factors, or help balancing the repair mechanism; thus inhibiting extensive scar formation. In this article, we have reviewed the latest treatment methods, as well as molecular and cellular reactions, which lead to the formation of hypertrophic scars and keloids.
