Prolactin level changes in pemphigus vulgaris: A cohort study
Narges
Ghandi
author
Shaghayegh
Tavassoli
author
Maryam
Ghiasi
author
Vahideh
Lajevardi
author
Robabeh
Abedini
author
Hamid-Reza
Tohidinik
author
Maryam
Daneshpazhooh
author
text
article
2016
eng
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
19
v.
2
no.
2016
35
39
https://www.iranjd.ir/article_99524_c19dc32ace1e83395a9365db56150da4.pdf
Relationship of blood types (ABO/Rh) with recurrent aphthous ulcers: A case-control study
Rezazadeh
Fahimeh
author
Salah
Shilan
author
Bahareh
Nazemi Salman
author
Ebrahim
Shahdadi
author
text
article
2016
eng
Background: Recurrent aphthous stomatitis (RAS) is among the most common oral lesions and pain is often the chief complaint of patients. The main etiology of RAS is unknown but several predisposing factors have been suggested. This study aims to assess the correlation of blood types (ABO/Rh) with RAS. Methods: We conducted this prospective screening study on 50 patients with RAS and 50 controls. Both groups received a questionnaire and underwent serum screening for detection of blood t
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
19
v.
2
no.
2016
40
44
https://www.iranjd.ir/article_98286_523bd05023ef58aefb4e2a8cdd4dd5c9.pdf
Demographic and histopathologic characteristics of Marjolin’s ulcers in Razi Hospital, Tehran, Iran: A 5-year survey
Ehsani
Amir Houshang
author
Noormohammadpour
Pedram
author
Nasiri
Nafiseh
author
Faraz
Parastoo Tavasoli
author
Goodarzi
Azadeh
author
text
article
2016
eng
Background: Approximately 0.77% to 2% of cutaneous ulcers and post-burn scars will develop malignant degeneration. When squamous cell carcinoma (SCC) emerges in a chronic scar or ulcer, it often is referred to as Marjolin’s ulcer (MU). Methods: This cross-sectional study assessed demographic information and pathological features of MU in Razi Hospital during 2009 to 2014. We reviewed 5150 chronic scar/ulcer cases and found 30 MU cases. Results: Patients had an average age of 59.2±19.9 years. Most cases were males Among 30 cases of MU, well-differential SCC accounted for 43.3% of cases. Moderately-differentiated SCC comprised 13.3% of cases, whereas there was invasive SCC in 10% of MUs. Only 3.3% of patients showed poorly-differentiated SCC and 9 (30%) had undifferentiated SCC. The average latency between burn and malignancy was 32.4±18.5 years In the majority (90%) of cases, the initial injury was a burn. The lower and upper limbs comprised 53.3% and 26.7% of cases, respectively. There was one case with a history of melanoma. Among the 4 measured concurrent risk factors for malignancy, sun exposure was the most prevalent. Conclusion: Since there is a high possibility of SCC formation in burn lesions and other identical lesions, rapid follow-up and appropriate treatment in acute burn lesions is necessary.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
19
v.
2
no.
2016
45
49
https://www.iranjd.ir/article_98287_f892f974dc8638f93fb41eaa1415aa2d.pdf
Evaluation of the efficacy of integrative programs in improving diabetic foot ulcers’ outcomes: A cross-sectional study
Aminian
Neda
author
Momeni
Mahnoush
author
Ranjpoor
Faraz
author
Eidipoor
Hoda
author
Rahbar
Hossein
author
text
article
2016
eng
Background: Treatment of a diabetic foot is a principal step in rehabilitative approaches to the complications of diabetes mellitus. Use of integrative educational courses for diabetic patients is dependent on several factors such as cultural entities of the population, patient perceptions of classes, and their previous trainings about diabetes and related complications. The aim of this study was to determine the efficacy of integrative programs to improve diabetic patients’ outcomes for wound care. Methods: We included 100 patients with diabetic wounds from August, 2014–December, 2014. Resources in this study included educational classes, brochures, and pamphlets. We implemented the educational course for three months in 50 patients and compared the results with 50 controls who received no educational course. The educational course was conducted over a three-month period and we evaluated reduction of HbA1C, fasting blood sugar (FBS), 60-second Diabetic Foot Screen score, STONES (Size, Temperature, Os [bone], New areas of breakdown, Exudate, erythema, edema, Smell) and NERDSS (Non-healing wound, Exudative wound, Red and bleeding wound, Debries in the wound, Smell form the wound) parameters implemented for evaluation of infectious diabetic wounds. Results: We followed STONES and NERDS changes (positive to negative) in 42 (84%) patients from the intervention group and 21 (42%) control group patients (P=0.001). Reduction in the 60-second Diabetic Foot Screen score was 34 (68%) for the intervention group and 24 (48%) in the control group (P=0.03). Conclusion: Possibly the use of interventional educational programs is effective in reduction of harm in patients with diabetic wounds, which will lead to decreased infections and better dynamic conditions.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
19
v.
2
no.
2016
50
53
https://www.iranjd.ir/article_98288_cf0b00c15d547dff4136e38a8b7f7c70.pdf
Tinea incognito simulating dermatitis herpetiformis: An unusual case report
Jowkar
Farideh
author
Saki
Nasrin
author
Derayesh
Mohmmad
author
Aslani
Fatemeh Sari
author
text
article
2016
eng
Tinea incognito is a dermatophyte infection of the skin with an atypical presentation attributed to inappropriate treatment with immunosuppressive medications. In thi
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
19
v.
2
no.
2016
54
56
https://www.iranjd.ir/article_98289_76141709be5e75e5f698ce403bd490a9.pdf
A rare ophthalmologic disorder: Gyrate atrophy with sparse hair
Namazi
Nastaran
author
Golfeshan
Atefe
author
Saghi
Bita
author
text
article
2016
eng
Gyrate atrophy (GA) is a rare, progressive metabolic choroid and retinal degeneration that results from a deficiency of the pyridoxal phosphate-dependent mitochondrial matrix enzyme ornithine aminotransferase. Here, we report the case of a 40-yearold woman who presented with a gradual decline in visual acuity since puberty, along with a history of high myopia and cataract surgery. She was admitted to the Dermatology Clinic with chief complaints of sparse hair on her scalp, eyelids, eyebrows and other areas of the body for the previous 5 years. Physical examination showed that scalp hair along with hair from other parts of her body were fine, straight, and sparse with areas of non-well defined alopecia. Hyperornithinemia was documented during laboratory evaluation of the patient.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
19
v.
2
no.
2016
57
59
https://www.iranjd.ir/article_98290_4436267401ca6201315916d79ead8895.pdf
Transgrediens et progrediens palmoplantar keratoderma of Sybert: Four cases in a single family
Tiwary
Anup Kumar
author
Mishra
Dharmendra Kumar
author
text
article
2016
eng
Palmoplantar keratoderma of Sybert (PPK of Sybert) or Sybert’s keratoderma was first documented by Virginia Sybert in 1988. Due to the high degree of similarity, it was previously considered to be Greither’s keratoderma, an established entity at that time. Currently, clinical and ultrastructural studies distinguish between the two disorders. Sybert’s keratoderma is an extremely rare type of keratoderma with an autosomal dominant mode of inheritance caused by mutations to the keratin 1 gene along with severe bilateral involvement of the palms and soles with a tendency for proximal extension and natal cleft in the absence of systemic manifestation. To the best of our knowledge, there are less than 20 cases of PPK of Sybert reported in the literature. Here we discuss an extremely rare familial PPK of Sybert that has affected 4 family members. The cases presented with symmetrical, severe involvement of their palms, soles, and knees with the development of pseudoainhum and autoamputation of the fingers and/or toes.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
19
v.
2
no.
2016
60
64
https://www.iranjd.ir/article_98291_15448a90defcb921e3d84d3854ccb15e.pdf
Serum prolactin level in psoriasis
Wiwanitkit
Viroj
author
text
article
2016
eng
The recent report, “Serum prolactin level in psoriasis”, is very interesting 1. Ghiasi et al. concluded that “it seems that while intracutaneous prolactin may contribute to the pathogenesis of psoriasis, the probable role of pituitary-produced circulating prolactin in the disease process needs further investigation .” There are some concerns on this report. First, although Ghiasi et al. have studied serum prolactin, they based their conclusion on intracutaneous prolactin. The serum prolactin is not the same as intracutaneous prolactin. The serum prolactin can be affected by several physiological and pathological factors. In fertile females, variations of baseline serum prolactin can be expected. Indeed, for psoriasis, there are previous reports on prolactin with controversial results. The difference in baseline pathophysiological conditions of psoriatic patients can be a good explanation for the different findings on prolactin levels in patients.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
19
v.
2
no.
2016
65
65
https://www.iranjd.ir/article_98292_21a46f6cf3b909f1e8e05dc81d20298f.pdf