Validity and reliability of Persian Version of 12-Item Pruritus Severity Score Questionnaire in the Hemodialysis Patients with Uremic Pruritus
Paria
Baharvand
Department of Clinical Pharmacy,
School of Pharmacy, Tehran
University of Medical Sciences,
Tehran, Iran
author
Ayda
Esmaeili
Department of Clinical Pharmacy,
School of Pharmacy, Urmia
University of Medical Sciences,
Urmia, Iran
author
Mohammad Reza
Abbasi
Dialysis Association, Imam
Khomeini Hospital, Tehran
University of Medical Sciences,
Tehran, Iran
author
Soha
Namazi
Department of Clinical Pharmacy,
School of Pharmacy and Research
Center for Rational Use of Drugs,
Tehran University of Medical
Sciences, Tehran, Iran
author
text
article
2021
eng
Background: The 12-Item Pruritus Severity Scale (12-PSS) is a multidimensional tool that evaluates pruritus intensity and duration along with an assessment of psychometric properties such as the patient´s mood, daily activities, and sleep pattern. Given its chronicity, uremic pruritus has a substantial impact on quality of life, so it is worth having a valid Persian questionnaire for assessing the various aspects of pruritus. This study was designed to evaluate the validity and reliability of the translated 12-PSS in hemodialysis patients with chronic uremic pruritus.
Methods: Participants in this cross-sectional study were hemodialysis patients with uremic pruritus who were referredto the dialysis departments of three hospitals in Tehran, Iran. Following forward-backward translation of the 12-PSS to and from Persian, we assessed its content validity index (CVI) and reliability. Finally, we asked patients to respond to questions using both the Visual Analog Scale (VAS) and the 12-PSS.
Results: Overall, 195 eligible patients participated in this study. The average age was 55.08 ± 12.34 years. The internalconsistency (Cronbach’s alpha) of the 12-PSS was found to be 0.88, indicating strong consistency. The mean VAS and 12-PSS scores were 6.40 ± 2.63 and 11.52 ± 3.91, respectively, and the correlation between VAS and the total raw points of the pruritus intensity domain of the 12-PSS (questions 9 and 10) was strong(P-value < 0.05, r = 0. 90).
Conclusions: This study showed that the translated form of the 12-PSS questionnaire has acceptable validity and reliability and has a strong correlation with the VAS in assessing pruritus intensity.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
73
79
https://www.iranjd.ir/article_132450_752483fcb5852cbb702dc5cf12c4e2a4.pdf
dx.doi.org/10.22034/ijd.2021.221589.1036
Study of total serum immunoglobulin E level and prevalence of atopy in alopecia areata patients
Nadia
Elsherif
Dermatology Department, Faculty
of Medicine, Benghazi University,
Benghazi, Libya
author
Salwa
El-Dibany
Dermatology Department, Omar El-
Mukhtar University, Al-Beida, Libya
author
Azza
Greiw
Department of Family and
Community Medicine, Faculty of
Medicine, Benghazi University,
Benghazi, Libya
author
text
article
2021
eng
Background: Alopecia areata (AA) is non-scarring hair loss. Its etiopathology is not fully known, most evidence considered AA an immunologically mediated disease. To compare serum levels of total immunoglobulin E (IgE) between AA patients and healthy subjects, and to assess whether AA is associated with atopy.
Methods: 50 AA patients and 50 healthy subjects were included in this study. Presence of atopy was elicited by detailed family and/ or personal history of atopy. Clinically patients were divided into 2 groups: patients with single patch of AA (alopecia unilocularis, AU), or with multiple patches (alopecia multilocularis, AM). Serum levels of IgE were measured in both groups.
Results: Serum levels of total IgE were significantly higher in patients than in controls (178 ± 154 ku/l vs. 118 ± 57 ku/l; P < 0.05). Evidence of atopy was present in 48% of AA patients compare to 18% of control subjects (P < 0.05). Patients with disease duration more than one year had significantly higher serum IgE levels (P < 0.05), and patients with AM had significantly higher serum IgE levels than patients with AU (267 ± 189 ku/l vs. 102 ± 32.3 ku/l; P < 0.05). Mean value of serum IgE did not vary significantly with patient’s age at onset, gender, history of atopy or family history of AA. Atopy was significantly associated with AM.
Conclusion: Total serum IgE is elevated in AA patients with significant association with severe and chronic disease irrespective of the presence of atopy. Atopic diseases were more frequent in AA patients with severe clinical presentation.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
80
84
https://www.iranjd.ir/article_132451_1a285ae75e82734ba022204819667ec7.pdf
dx.doi.org/10.22034/ijd.2021.132451
Incomplete excision of basal cell carcinoma and its associated risk factors
Yalda
Nahidi
Department of Dermatology,
Cutaneous Leishmaniasis Research
Center, Mashhad University of
Medical Sciences, Mashhad, Iran
author
Naser
Tayyebi Meibodi
Cutaneous Leishmaniasis Research
Center, Mashhad University of
Medical Sciences, Mashhad, Iran
author
Habiballah
Esmaeili
Department of Social Sciences,
Faculty of Health, Mashhad
University of Medical Sciences,
Mashhad, Iran
author
Zahra
Tafazzoli
Department of Dermatology,
Cutaneous Leishmaniasis Research
Center, Mashhad University of
Medical Sciences, Mashhad, Iran
author
text
article
2021
eng
Background: Basal cell carcinoma (BCC) is the most common type of skin tumor. Surgical removal has remained the gold standard of treatment for BCC, but incomplete removal is an important clinical challenge. The goal of our study was to evaluate the incomplete excision of BCC and the factors affecting it.
Methods: In this retrospective study, 361 histological samples of BCC excisions referred to the Pathology Department of Imam Reza Hospital, Mashhad, Iran, from 2004 to 2018 were reviewed. Data including age, gender, tumor site, size, histopathologic subtype, surgical margin involvement, and the surgeon’s specialty were recorded.
Results: The incomplete removal rate was 20%. Ten percent of the lesions had deep margin involvement, 5.8% had lateral margin involvement, and both margins were involved in 4.2% of cases. Incomplete excision had a significant relationship with the following variables: nodular, mixed, and sclerosing types; the 60-70 years age group; lesions larger than 2 cm, location in nose and canthi; and excision by an otorhinolaryngologist, ophthalmologist, or dermatologist.
Conclusion: In this study, the frequency of incomplete excision was relatively high compared with other studies. Therefore, it is suggested to perform a diagnostic biopsy before the complete excision of BCC. Excision with a wider margin or using Mohs surgery is recommended for midface lesions, older individuals, nodular, mixed, or sclerosing lesions, and for tumors larger than 2 cm.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
85
90
https://www.iranjd.ir/article_132454_6004e01858d0564a79fbd0d55c4f1685.pdf
dx.doi.org/10.22034/ijd.2021.132454
Efficacy and safety of carboxytherapy for treatment of striae: a clinical trial study
Yalda
Nahidi
Department of Dermatology,
Cutaneous Leishmaniasis Research
Center, Mashhad University of
Medical Sciences, Mashhad, Iran
author
Elahe
Abdali
Dermatologist, Mashhad, Iran
author
Masoud
Maleki
Department of Dermatology,
Cutaneous Leishmaniasis Research
Center, Mashhad University of
Medical Sciences, Mashhad, Iran
author
Azadeh
Saki
Department of Community Medicine,
School of Medicine, Mashhad
University of Medical Sciences,
Mashhad, Iran
author
Pouran
Layegh
Department of Dermatology,
Cutaneous Leishmaniasis Research
Center, Mashhad University of
Medical Sciences, Mashhad, Iran
author
text
article
2021
eng
Background: Striae is a common condition that is relatively difficult to treat. Recently, carboxytherapy was proposed as a treatment modality. This study aimed to evaluate the therapeutic effect of carboxytherapy in patients with striae.
Methods: This was a pilot clinical study. Patients were treated with 10 sessions of carboxytherapy every week. The patients were photographed at the onset of the treatment course, before each treatment session, and three months after the last ones. Two dermatologists compared the images of each patient before and three months after treatment and evaluated the treatment response based on the following scores: I, no improvement (0%);II, poor (1% to 25%); III, fair (26% to 50%); IV, good (51% to 75%); and V, excellent improvement (76% to 100%). Furthermore, patients’ satisfaction with therapy outcome was recorded on a scale of 0 to 10.
Results: 15 patients were enrolled in this study; 2 (13.4%) were male and 13 (86.6%) were female. Three patients (20%) showed good response, one (6.7%) had a relatively good response, two showed (13.3%) poor response, and seven (46.6%) had no response to treatment. Analysis of the association of carboxytherapy outcomewith different patients’ characteristics showed no statistically significant correlation (P > 0.05).
Conclusions: Although carboxytherapy therapy did not result in a significant response in the majority of our patients, it is somehow capable of improving the striae in some patients. Further studies with bigger sample sizes may be required to ensure the efficacy of this modality in the treatment of striae.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
91
96
https://www.iranjd.ir/article_132455_accd22612d22f7ea624a157add1d9bde.pdf
dx.doi.org/10.22034/ijd.2021.132455
Study of vitamin D deficiency in patients with alopecia areata attending a dermatology center in Iran
Robabe
Abedini
Department of Dermatology, Tehran
University of Medical Sciences, Razi
Hospital, Tehran, Iran
author
Saeed
Shakiba
School of Medicine, Tehran
University of Medical Sciences,
Tehran, Iran
author
Narges
Ghandi
Department of Dermatology, Tehran
University of Medical Sciences, Razi
Hospital, Tehran, Iran
author
Farnaz
Yazdaniamjad
School of Medicine, Tehran
University of Medical Sciences,
Tehran, Iran
author
Nazgol-Sadat
Haddadi
School of Medicine, Tehran
University of Medical Sciences,
Tehran, Iran
author
Maryam
Nasimi
Department of Dermatology, Tehran
University of Medical Sciences, Razi
Hospital, Tehran, Iran
author
text
article
2021
eng
Background: Alopecia areata (AA) is an autoimmune disease involving the inflammation of hair follicles. In many autoimmune diseases, inadequate levels of vitamin D have been reported. We aimed to determine the association between vitamin D levels and AA.
Methods: In this case-control study, 50 AA patients and 50 controls were assessed regarding serum levels of 25-hydroxy vitamin D [25-(OH)-D3]. The levels of 25-(OH)-D3 were classified as deficient ( < 20 ng/ml), insufficient (20 to 30 ng/ml), and sufficient ( > 30 ng/dl). The severity of the disease was scored according to the Severity of Alopecia Tool (SALT).
Results: The serum level of 25-(OH)-D3 was significantly lower in AA cases compared with the control group. Patients with the totalis or universalis pattern of hair loss had lower levels of 25-(OH)-D3 relative to patients with the patchy or ophiasis type of AA. Moreover, severe cases showed significantly lower levels of vitamin D relative to mild and moderate cases. We found a significant inverse association between 25-(OH)-D3 level and age. We found no association between serum levels of 25-(OH)-D3 and gender, disease duration, disease recurrence, nail involvement, or positive family history of AA.
Conclusion: AA patients had lower serum levels of vitamin D, though this did not contribute to the severity or duration of disease or pattern of hair loss. More studies are required to evaluate the role of vitamin D supplementation in the pathophysiology of AA.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
97
101
https://www.iranjd.ir/article_132456_64c4bc6b057ea4e2fa57baeba05592a7.pdf
dx.doi.org/10.22034/ijd.2021.132456
Therapeutic effect of bleomycin tattooing combined with trichloroacetic acid and shaving on treatment-resistant plantar warts
Ali
Asilian
Department of Dermatology, School
of Medicine, Isfahan University of
Medical Sciences, Isfahan, Iran
author
Zabihollah
Shahmoradi
Department of Dermatology, School
of Medicine, Isfahan University of
Medical Sciences, Isfahan, Iran
author
Shahryar
Rahmani
School of Medicine, Isfahan
University of Medical Sciences,
Isfahan, Iran
author
Hossein
Hafezi
Department of Dermatology, School
of Medicine, Isfahan University of
Medical Sciences, Isfahan, Iran
author
Samaneh
Mozafarpoor
Department of Dermatology, School
of Medicine, Isfahan University of
Medical Sciences, Isfahan, Iran
author
text
article
2021
eng
Background: Bleomycin is used for the treatment of warts. However, only its injected form can be used due to systemic use side effects, and plantar warts have a high recurrence rate following administration of bleomycin tattooing alone. To find an effective alternative with fewer side effects, we decided to investigate the effectiveness of bleomycin tattooing combined with trichloroacetic acid (TCA) and shaving in the management of treatment-resistant plantar warts.
Methods: The patients with treatment-resistant plantar warts entered the present quasi-experimental study. the wart site was shaved ahead of bleomycin tattooing and TCA peeling. This treatment was provided at one-month intervals and was repeated a maximum of four times. Patients were followed for six months after completion of the therapy. Finally, the patients’ data were completed according to photographs (monthly photos taken of lesions) and careful examinations.
Results: The present study involved 56 patients with a mean age of 25.75 ± 12.22 years. Twelve patients (21.4%) recovered after the first treatment; 14 (25%) needed the second treatment, 12 (21.4%) needed the third, 10 (17.9%) the fourth, and eight (14.3%) did not recover after the fourth treatment. The recovery rate was 21.4% with one, 45.4% with two, 66.8% with three, and 85.7% with four treatment sessions.
Conclusion: The combination treatment of bleomycin plus TCA and shaving led to a remarkable recovery from treatment-resistant plantar warts (21.4% recovery with the first treatment session and up to 85.7% recovery after four sessions). The treatment included tattooing and local injections, leaving few side effects.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
102
109
https://www.iranjd.ir/article_132457_becdb7a7a2c8a8532a4e45a144063177.pdf
dx.doi.org/10.22034/ijd.2020.235939.1147
Association of functional dyspepsia with selected dermatology complaints and sleep disturbances based on traditional Persian medicine
Mohammad Mahdi
Parvizi
Molecular Dermatology Research
Center, Shiraz University of Medical
Sciences, Shiraz, Iran
author
Mahshad
Shabani
Department of Dermatology, School
of Medicine, Shiraz University of
Medical Sciences, Shiraz, Iran
author
Nasrin
Saki
Molecular Dermatology Research
Center, Shiraz University of Medical
Sciences, Shiraz, Iran
author
Shirin
Rajabi
Research Center for Traditional
Medicine and History of Medicine,
School of Medicine, Shiraz
University of Medical Sciences,
Shiraz, Iran
author
Thomas
Rampp
Department of Internal and
Integrative Medicine, Kliniken
Essen-Mitte, Faculty of Medicine,
University of Duisburg-Essen,
Essen, Germany
author
Mehdi
Pasalar
Research Center for Traditional
Medicine and History of Medicine,
School of Medicine, Shiraz
University of Medical Sciences,
Shiraz, Iran
author
text
article
2021
eng
Background: Functional dyspepsia (FD) is a common disorder of the upper gastrointestinal tract. Several documents in conventional medicine claim an association between FD, sleep disturbance, and some dermatological conditions, but there is still debate about these relationships. This study aimed to measure the association between FD and some skin problems and sleep indices based on the attitudes of traditional Persian medicine.
Methods: This study was carried out on patients with the diagnosis of FD and healthy people. The study populationconsisted of patients who referred to the gastroenterology clinic of Shiraz University of Medical Sciences (Shiraz, Iran) from July to December 2019. To diagnose dyspepsia, we used Rome III criteria. Skin problems and sleep indices were evaluated using a validated researcher-made questionnaire. P-values of ≤0.05 were considered significant.
Results: Overall, 160 patients (46 men and 116 women) with FD and 155 healthy individuals (36 men and 119 women) were enrolled in the study. There were significant differences between patients and healthy individuals in terms of dryness of skin (P = 0.001), oily hair, deep sleep, long sleep, insomnia, difficulty sleeping, and nightmares (p≤0.001). On the other hand, there were no significant differences between the groups in intermittent sleeping (P = 0.116) and periorbital edema after sleeping (P = 0.195).
Conclusions: According to the results of this study, it seems that there is a positive relationship between FD and some dermatological and sleeping indices based on traditional Persian medicine resources.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
110
116
https://www.iranjd.ir/article_132458_88a5c2e3f61926ba47f8b2dad63527a1.pdf
dx.doi.org/10.22034/ijd.2020.242818.1187
Genotype distribution of human papillomavirus in anogenital warts in Guilan province, northern Iran
Narges
Alizadeh
Department of Dermatology, Medical
School, Guilan University of Medical
Sciences, Rasht, Iran
author
Javad
Golchai
Department of Dermatology, Medical
School, Guilan University of Medical
Sciences, Rasht, Iran
author
Atefeh
Ghanbari
Shahid Beheshti Nursing and
Midwifery School, Guilan University
of Medical Sciences, Rasht, Iran
author
Behrooz
Golchai
Department of Dermatology, Medical
School, Guilan University of Medical
Sciences, Rasht, Iran
author
Shirin
Zaresharifi
Skin Research Center, Shahid
Beheshti University of Medical
Sciences, Tehran, Iran
author
text
article
2021
eng
Background: Anogenital warts are the most prevalent sexually transmitted disease worldwide and are caused by human papillomavirus (HPV). There are more than 100 different types of HPV, of which certain types make the patient more susceptible to malignant neoplasms. This study aimed to determine the frequencies of specific types of HPV in anogenital warts.
Methods: This study included 157 patients diagnosed with anogenital warts that underwent HPV DNA detection using polymerase chain reaction (PCR) with INNO-LiPA genotyping assay.
Results: Of 157 patients with anogenital warts, 122 samples (77.7%) were positive for HPV, with some patients showing mixed HPV subtypes. HPV 6 (n = 99; 68.3%) and HPV 11 (n = 13; 8.9%) were the most prevalent types. 101 patients were male (64.3%). The mean age was 32.02 ± 10.06 years (range: 2 to 72 years). Most patients were infected with the low-risk types (80%); the high-risk HPV type 16 was significantly more common among women (P = 0.0001).
Conclusion: This study showed the higher relative frequency of HPV6 and HPV11 in anogenital warts in Guilan, northern Iran. The frequency of genital HPV infection appears to be higher among men, but the frequency of high-risk types seems to be higher among women.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
117
120
https://www.iranjd.ir/article_132459_84084219eb531fb42589d97a0a748beb.pdf
dx.doi.org/10.22034/ijd.2020.251941.1236
Thermal therapy with radiofrequency for the treatment of basal cell carcinoma: a pilot study
Leila
Izadi Firouzabadi
Razi Hospital, Tehran University of
Medical Sciences, Tehran, Iran
author
Hamidreza
Mahmoudi
Razi Hospital, Tehran University of
Medical Sciences, Tehran, Iran
author
Ali
Khamesipour
Center for Research & Training in
Skin Disease & Leprosy, Tehran
University of Medical Sciences,
Tehran, Iran
author
Abhay
Satoskar
Department of Pathology, The Ohio
State University, Columbus, USA
author
Alireza
Firooz
Center for Research & Training in
Skin Disease & Leprosy, Tehran
University of Medical Sciences,
Tehran, Iran
author
text
article
2021
eng
Background: Basal cell carcinoma (BCC) is the most common type of skin malignancy. Hyperthermia is used as adjuvant therapy together with radiotherapy and chemotherapy in the treatment of some cancers. This study aimed to evaluate the efficacy and safety of thermotherapy in the treatment of BCCs.
Methods: This pilot trial was carried out on five patients with nodular or superficial BCCs on the scalp and face.Thermotherapy was done at 50° C for a duration of 30 seconds with a radiofrequency device (Thermomed 1.8 thermosurgery technologies). Thermotherapy treatment was applied only in one session. The first follow-up was one week after the procedure and then every month for six months. The last follow-up was one year after the procedure.
Results: All patients showed clearance of the tumors. Blisters, ulcers, crusts, and necrosis were the side effects, which healed with acceptable degrees of scarring. No recurrence was observed at the end of the study.
Conclusion: Thermotherapy was safe and efficacious for the treatment of BCCs on the scalp and face. It should be considered especially for the low-risk subtypes of this cancer.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
121
126
https://www.iranjd.ir/article_132460_b766867f3763bfa3d333766e4e6f32e7.pdf
dx.doi.org/10.22034/ijd.2020.250152.1226
Assessment of the psychosocial effects of hand dermatitis among healthcare workers during the COVID-19 pandemic
Mohammad Reza
Pourani
Skin Research Center, Shahid
Beheshti University of Medical
Sciences, Tehran, Iran
author
Fahimeh
Abdollahimajd
Skin Research Center, Shahid
Beheshti University of Medical
Sciences, Tehran, Iran
author
text
article
2021
eng
Hand hygiene is one of the most crucial measures against coronavirus disease 2019 (COVID-19) transmission; however, frequent handwashing may lead to contact dermatitis causing many problems. Occupational hand dermatitis is a relatively common but challenging issue that imposes a negative effect on the quality of life, work performance, and adherence to hygiene principles. We performed a cross-sectional study to assess the psychosocial impacts of hand dermatitis on healthcare workers (HCWs) using an online Persian version of the Nordic Occupational Skin Questionnaire (NOSQ-2002). Sixty-three from a total of 390 HCWs (21%) reported that hand eczema had adverse effects on their occupation, such as a necessity to use gloves (17.3%) and decreased adherence to hand hygiene (14%). HCWs reported a higher exacerbation of hand dermatitis in winter (40.3%) and fall (24.7%). Hand dermatitis exerted a significant impact on sporting activities, sleep, social life, mood, and sex in 17.7%, 43.3%, 44.3%, 66%, and 11.7% of HCWs, respectively. It seems that hand dermatitis-related impairment of the mentioned activities has increased in HCWs during the COVID-19 pandemic.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
127
131
https://www.iranjd.ir/article_132469_e1203ddcc003050eed604c70495b06fb.pdf
dx.doi.org/10.22034/ijd.2021.272982.1321
Mini-review: the p53 gene as a bona fide tumor suppressor gene in human skin cancers
Neda
Hosseini Sarani
Faculty of Paramedical Sciences,
Shiraz University of Medical
Sciences, Shiraz, Iran
author
Mehran
Ataei
Department of Biology, Faculty of Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran
author
Tannaz
Akbari Kolagar
Faculty of Biological Sciences, Tehran North Branch, Islamic Azad University, Tehran, Iran
author
Elaheh
Heydari
Faculty of Biological Sciences, Tehran North Branch, Islamic Azad University, Tehran, Iran
author
Maryam
Farzaneh
Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
author
Amir
Anbiyaiee
Department of Surgery, School
of Medicine, Ahvaz Jundishapur
University of Medical Sciences,
Ahvaz, Iran
author
text
article
2021
eng
Skin cancer is the out-of-control growth of skin cells that can be divided into keratinocyte carcinoma (non-melanoma) and malignant melanoma. Basal cell carcinoma (BCC) and squamous cell carcinomas (SCC) are the most common forms of keratinocyte carcinoma that may grow to involve other parts of the body. These cancers are caused by exposure to ultraviolet (UV) light, toxic substances, and a family history of skin problems. Different signaling pathways are likely to be involved in skin cancer. The TP53 gene (the gene coding for cellular tumor protein p53) is among the most diverse and complex molecules involved in cellular functions. The p53 pathway can initiate DNA replication, modulate cell cycle events, and interact with tumor suppressor genes (TSGs). Mutations in TP53 can occur in numerous human cancers, leading to cellular immortalization, inappropriate proliferation, and genomic instability. TP53 plays a big role in both melanoma and non-melanoma skin cancers. Despite the intensive investigation to clarify the impact of TP53 mutations in the induction of skin cancer, much remains to be elucidated. In this mini-review, we will discuss the protective role of p53 as a bona fide tumor suppressor gene in human skin cancers.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
132
138
https://www.iranjd.ir/article_132461_16aaa54556ee2a358f18da01e2764768.pdf
dx.doi.org/10.22034/ijd.2021.132461
The biological debridement of bedsore with the larvae of Lucilia sericata: a case report
Kamran
Akbarzadeh
Department of Medical Entomology
and Vector Control, School of Public
Health, Tehran University of Medical
Sciences, Tehran, Iran
author
Abedin
Saghafipour
Department of Public Health,
Faculty of Health, Qom University of
Medical Sciences, Qom, Iran
author
text
article
2021
eng
Bedsores are caused by decreased tissue perfusion due to prolonged pressure on the skin and represent one of the problems of immobilized patients, including hospitalized ones. This study reports the successful treatment of a patient with bedsore wounds using the larvae of the fly Lucilia sericata. The study focused on a 64-year-old man residing in Qom (a city in central Iran), who was hospitalized for 45 days at Qom Shahid Beheshti Hospital in November 2019 because of cardiovascular disease and chronic obstructive pulmonary disease (COPD). He had a pressure ulcer of about 9.5 cm in diameter on the skin overlying the sacrum. After showing resistance to honey dressing and conventionalantibiotic treatments, maggot therapy was recommended. This procedure was done by releasing the larvae of L. sericata 12 times every three days. The removal of necrotic tissues and the appearance of the granulated tissues were recorded using a ruler as an indicator of healing. After 12 sessions of larval treatment, the wound surface considerably reduced and was finally healed. Thus, it can be argued that maggot debridement therapy (MDT) is an effective treatment for bedsores and can be recommended to physicians as an adjuvant treatment for complex and resistant ulcers.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
139
142
https://www.iranjd.ir/article_132462_3ffdf11bca48e0ee5ed71d738cf8c1f3.pdf
dx.doi.org/10.22034/ijd.2021.132462
Basal cell carcinoma on the conchal bowl of the ear of a young man
Mina
Almasi-Nasrabadi
Skin Research Center, Shahid
Beheshti University of Medical
Sciences, Tehran, Iran
author
Reza
Robati
Skin Research Center, Shahid
Beheshti University of Medical
Sciences, Tehran, Iran
author
text
article
2021
eng
Basal cell carcinoma (BCC) is the most common form of nonmelanoma skin cancer. A review of the literature revealed only a few reports of BCC on the auricle or conchal bowl, usually occurring in elderly patients. Herein, we report an exceptional case of BCC in a young man with an unusual anatomical location of the tumor as a solitary erythematous to black-colored plaque located in the conchal bowl of his right ear. By thoroughly reviewing the literature, there was no other documented case of BCC located in the conchal bowl of the ear of a young adult. Dermatologists should be aware that skin tumors may also occur in uncommon anatomical locations and with unusual presentations in the young population, even if they have no known predisposing factor. Unusual presentations make clinical suspicion of skin tumors very difficult, so these lesions can easily be missed. Early diagnosis can prevent further growth, extensive destruction, and severe consequence of invasive treatments.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
143
146
https://www.iranjd.ir/article_132463_14ea2a11b3898cecd739dd52bac34d59.pdf
dx.doi.org/10.22034/ijd.2021.132463
Trichilemmal carcinoma in an Iranian patient: reporting a rare skin tumor
Ebrahim
Esmati
Radiation Oncology Research
Center (RORC), Cancer Institute of
Iran, Tehran University of Medical
Sciences, Tehran, Iran
author
Mojtaba
Vand Rajabpour
Radiation Oncology Research
Center (RORC), Cancer Institute of
Iran, Tehran University of Medical
Sciences, Tehran, Iran
author
Mohammad
Shirkhoda
Cancer Research Center, Cancer
Institute of Iran, Tehran University of
Medical Sciences, Tehran, Iran
author
Vahid
Soleimani
Pathology Department, Cancer
Institute of Iran, Tehran University of
Medical Sciences, Tehran, Iran
author
Maryam
Garousi
Radiation Oncology Department,
Iran University of Medical Sciences,
Tehran, Iran
author
text
article
2021
eng
Trichilemmal carcinoma is a rare tumor of the outer sheath cells of hair follicles. These tumors occur on the sun-exposed skin of the elderly in the majority of cases. The gross tumor demonstrates exophytic, polypoid, ulcerative, or nodular lesions with or without bleeding. Histopathologically, it is characterized by an anastomosing trabecular, diffuse, or lobular growth pattern with clear keratinization. A critical differential diagnosis is squamous cell carcinoma (SCC), where the prognosis of trichilemmal carcinoma is far better than SCC. Surgery is a significant and effective treatment for trichilemmal carcinoma cases, and recurrence after complete surgical resection with a negative margin is uncommon. Trichilemmal carcinoma is considered a low-grade tumor with low metastatic potential. This paper reports a 48-year-old Iranian male with trichilemmal carcinoma of the scalp treated with surgery, having no recurrence after three years of follow-up. The role of other treatment modalities like radiation, local therapy, and systemic therapy are also discussed.
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
147
149
https://www.iranjd.ir/article_132464_23ce28495ec7854cd451d932d95686fe.pdf
dx.doi.org/10.22034/ijd.2020.244451.1196
A long-standing plaque in the cutaneous upper lip of a late middle-aged man
Mohamad Reza
Namazi
Molecular Dermatology Research
Center, Shiraz University of Medical
Sciences, Shiraz, Iran
author
Maryam
Hadibarhaghtalab
Molecular Dermatology Research
Center, Shiraz University of Medical
Sciences, Shiraz, Iran
author
Uranus
Dasmeh
Department of Plastic Surgery,
Shiraz University of Medical
Sciences, Shiraz, Iran
author
Fatemeh
Sari Aslani
Pathology Department, Shiraz
University of Medical Sciences,
Shiraz, Iran
author
Kaveh
Taghipour
Molecular Dermatology Research
Center, Shiraz University of Medical
Sciences, Shiraz, Iran
author
text
article
2021
eng
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
150
152
https://www.iranjd.ir/article_132465_b37b4d2e38df94647cf855b6e02a7593.pdf
dx.doi.org/10.22034/ijd.2021.219539.1026
A middle-aged man with a distinct erythematous firm nodule on his scalp
Mohammad
Darayesh
Department of Dermatology, Shiraz
University of Medical Sciences,
Shiraz, Iran
author
Nasrin
Saki
Department of Dermatology, Shiraz
University of Medical Sciences,
Shiraz, Iran
author
Mojgan
Akbarzadeh
Department of Pathology, Shiraz
University of Medical Sciences,
Shiraz, Iran
author
Mahsa
Hosseini
Department of Internal Medicine,
Shiraz University of Medical
Sciences, Shiraz, Iran
author
text
article
2021
eng
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
153
155
https://www.iranjd.ir/article_132466_de8822bd132e6526e9c411bad69e04fa.pdf
dx.doi.org/10.22034/ijd.2020.256980.1268
Surgical pearl: a simplified technique of using disposable needles as electrodes
Muhammed
Mukhtar
Consultant Dermatologist, Mukhtar Skin Centre, Katihar
Medical College Road, Katihar, India
author
text
article
2021
eng
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
156
157
https://www.iranjd.ir/article_132467_fc207234812588ce222d997b26491865.pdf
dx.doi.org/10.22034/ijd.2021.132467
Letter regarding “Lichen planus pigmentosus successfully treated with conventional CO2 laser resurfacing”
Nasrin
Zand
Department of Medical Laser, Medical Laser Research
Center, Yara Institute, Academic Center for Education,
Culture and Research (ACECR), Tehran, Iran
author
Leila
Ataie Fashtami
Department of Regenerative Medicine, Royan Institute
for Stem Cell Biology & Technology, Academic Center
for Education, Culture and Research (ACECR),
Tehran, Iran
author
text
article
2021
eng
Iranian Journal of Dermatology
Iranian Society of Dermatology
2717-0721
24
v.
2
no.
2021
158
159
https://www.iranjd.ir/article_132468_34992f3eb48b62acf297afd011346ad1.pdf
dx.doi.org/10.22034/ijd.2021.265773.1303