@article { author = {Aryanian, Zeinab and Shahabandaz, Hosein and Abdollahzadeh Sangrody, Meysam and Shirzadian, Azar and Tirgartabari, Soodabeh and Bijani, Ali and Fahim, Shabnam and Etesami, Ifa and Azizpour, Arghavan and Goodarzi, Azadeh}, title = {Carotid doppler ultrasound evaluation in patients with lichen planus}, journal = {Iranian Journal of Dermatology}, volume = {22}, number = {4}, pages = {133-138}, year = {2020}, publisher = {Iranian Society of Dermatology}, issn = {2717-0721}, eissn = {2717-0721}, doi = {10.22034/ijd.2020.104823}, abstract = {Background: Lichen planus is a chronic inflammatory disease associated with an increased risk of subclinical atherosclerosis and cardiovascular diseases. This study aimed to evaluate patients with lichen planus using carotid Doppler ultrasound parameters.Methods: Forty patients with lichen planus and 40 controls were included in this study. Common carotid artery intima-media thickness (CIMT) and the number of atherosclerotic plaque weremeasured and compared to the control group. Total cholesterol, triglyceride, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels were measured. Leptin level (Pg/ml)was measured using the enzyme-linked immunosorbent assay (ELISA) method (Leptin ELISA kit, Orgenium, Finland).Results: Significant difference was found between the groups in terms of CIMT (P=0.005). The median range for blood leptin level, triglyceride, cholesterol, and LDL was higher for lichen planus patients than for controls. We found a significant difference between the severity of LP and CIMT (P=0.035). No statistical difference was found between LP and the number of atherosclerotic plaque.Conclusions: Our study suggested that measurement of the mean intima media wall thickness of the common carotid artery could be beneficial as a valuable method for early diagnosis of atherosclerosis in lichen planus.}, keywords = {Lichen Planus,common carotid artery,Doppler ultrasound}, url = {https://www.iranjd.ir/article_104823.html}, eprint = {https://www.iranjd.ir/article_104823_9c982e1a24bd55529a7eee1fc8e31b3e.pdf} }