@article { author = {Nastaran, Namazi and Sarah, Ershadi and Laya Rahbar, Nikoukar and Morteza, Ghassemipur}, title = {Classic Kaposi sarcoma presenting as elephantiasis nostras verrucosa}, journal = {Iranian Journal of Dermatology}, volume = {18}, number = {1}, pages = {25-28}, year = {2015}, publisher = {Iranian Society of Dermatology}, issn = {2717-0721}, eissn = {2717-0721}, doi = {}, abstract = {Kaposi sarcoma is a malignant disease that originates fromthe lymphatic system. Different epidemiological, clinical andhistopathological variants of this neoplasm have been identified.Classic Kaposi sarcoma is one of the four main clinico-epidemiologicvariants. Cutaneous lesions vary from pink patches to darkviolet plaques, nodules or polyps, depending on clinical variantand stage. Kaposi sarcoma with elephantiasis is reported in thecontext of AIDS. An 82-year-old male presented with a 2-yearhistory of progressive verrucous skin changes and non-pittingedema consistent with elephantiasis nostras verrucosa (ENV),secondary to Kaposi’s sarcoma. Past medical history, physicalexamination, lab tests and imaging ruled out common causes ofENV and anti-HIV antibody test was negative. Classic Kaposisarcoma was confirmed on biopsy. To the best of our knowledge,this study reports the first case of elephantiasis nostras verrucosain an HIV-negative patient with classic Kaposi sarcoma.}, keywords = {elephantiasis nostras verrucosa,Kaposi sarcoma,Lymphedema}, url = {https://www.iranjd.ir/article_98248.html}, eprint = {https://www.iranjd.ir/article_98248_4189dc0723190f24d73894f5e8377c69.pdf} }