%0 Journal Article %T A comparative study on the efficacy of intralesional injections of Bleomycin and Normal Saline in treatment of recalcitrant common warts on palm and dorsum of hand %J Iranian Journal of Dermatology %I Iranian Society of Dermatology %Z 2717-0721 %A Yazdanfar, A %A Karimirad, K %A Mani Kashani, Kh %D 2003 %\ 10/01/2003 %V 7 %N 1 %P 8-13 %! A comparative study on the efficacy of intralesional injections of Bleomycin and Normal Saline in treatment of recalcitrant common warts on palm and dorsum of hand %K Yazdanfar A %K Karimirad K %K Mani Kashani Kh %R %X Background: Wart is a common skin disease, and 8% of patients referred to dermatologists suffer from warts. Objective: To compare the efficacy of intralesional injections of bleomycin with normal saline in treatment of common resistant warts on palms and dorsum of hands. Patients & Methods: This study was a double blind, randomized, controlled clinical trial on 34 patients with common warts on palms and dorsum of their hands. These patients were randomly divided into two groups: 18 patients were treated with intralesional injections of bleomycin and 16 patients were treated with intralesional injections of normal saline. After 3 weeks of treatment, patients were evaluated and in case of unresponsiveness the second injection with the same medication was attempted. This group was visited again 3 weeks later and finally response to treatment ad possible complications were evaluated. Results: In bleomycin group 88.9% and in normal saline group 56.3% remitted (Fisher’s exact test, P<0.05). Conclusion: Intralesional bleomycin is an effective and low risk treatment of common resistant warts on palms and dorsum of hands. %U https://www.iranjd.ir/article_101094_4ea82f5a55e72ed11962687a66af7105.pdf