Iranian Society of Dermatology
Iranian Journal of Dermatology
2717-0721
23
3
2020
10
01
Association between metabolic syndrome and acne in teenage girls: a cross-sectional study
85
90
EN
Ghazal
Shariatpanahi
0000-0001-5778-6444
Department of Pediatric, Ziaeian Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
gshariatpanahi@yahoo.com
Rezvan
Hashemi
Department of Geriatric Medicine, Ziaeian Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
r_hashemi@yahoo.com
Mahsa
Asadabadi
Department of Pediatric, Ziaeian Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
mah.asadabadi@gmail.com
Nava
Shirzadi
Department of Pediatric, Ziaeian Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
n.shirzady@yahoo.com
Nazgol
Sadat Haddadi
Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran
nazgolhaddadi@gmail.com
Safoura
Shakoei
0000-0001-6790-7633
Department of Dermatology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
dr.shakoei@gmail.com
10.22034/ijd.2020.111544
<strong>Background: </strong>Acne is a common chronic inflammatory skin disease predominantly occurring during adolescence; this condition adversely affects a person’s self-esteem and can be associated with metabolic disorders. This study aimed to investigate the prevalence of metabolic syndrome and its components in adolescent girls with acne compared to a control group. <br /> <strong>Materials and Methods: </strong>In this cross-sectional study,105 adolescent girls aged 12-18 years were assigned to either the acne (case; n=55) or control group (n=50). The case group was selected from the Dermatology Department of a general hospital in Tehran, Iran, between January and August 2017. Acne lesions were confirmed and graded by a dermatologist. Clinical and biochemical parameters were evaluated for all participants.<br /> <strong>Results:</strong> The prevalence of metabolic syndrome in patients with and without acne was 18.2% and 14%, respectively. As a result, metabolic syndrome was not correlated with acne in adolescent girls (P=0.561). In addition, the mean body mass index (P=0.89), waist circumference (P=0.62), mean systolic and diastolic blood pressures (P=0.57 and 0.62, respectively), fasting blood sugar (P=0.59), total cholesterol, and low-density lipoprotein cholesterol levels were comparable between the studied groups (P>0.05). Moreover, triglyceride levels were significantly lower in the acne group (P=0.028), whereas this group featured a higher level of high-density lipoprotein cholesterol (P=0.02). However, the logistic regression results showed that none of the measured lipids were associated with acne.<br /> <strong>Conclusion: </strong>The findings indicated that metabolic syndrome and its components (representing metabolic imbalance) were not correlated with acne in adolescent girls.
Acne Vulgaris,Metabolic Syndrome,Adolescent
https://www.iranjd.ir/article_111544.html
https://www.iranjd.ir/article_111544_eca1c1f38385e78f3feed2a1a5f9e157.pdf
Iranian Society of Dermatology
Iranian Journal of Dermatology
2717-0721
23
3
2020
10
01
Quality of life of psoriatic patients and their acceptance of the disease
91
97
EN
Shrouk
Aladl
Dermatology Department, Meniat
ElNasr General Hospital, Ministry of
Population & Health, Meniat ElNasr,
Egypt
dr_sunrise_145@yahoo.com
Abdel-Hady
El-Gilany
0000-0001-9376-6985
Department of Community Medicine,
Faculty of Medicine, Mansoura
University, Mansoura, Egypt
ahgilany@gmail.com
Bothaina
Ghanem
Dermatology, Andrology & STDs
Department, Faculty of Medicine,
Mansoura University, Mansoura,
Egypt
dr_bothaina.mahrous@yahoo.com
Hassan
Fayed
Dermatology, Andrology & STDs
Department, Faculty of Medicine,
Mansoura University, Mansoura,
Egypt
fayedha2004@yahoo.com
10.22034/ijd.2020.111545
<strong>Background:</strong> Psoriasis and its acceptance adversely affect the patient’s quality of life. This study aims to measure quality of life of psoriatic patients, psoriasis disability index and acceptance of psoriasis as a disease and their associated factors as well as their interaction. <br /> <strong>Methods:</strong> A total of 125 psoriatic patients were included in the study. Socio-demographic and clinical data were collected. Psoriasis Area Severity Index (PASI), Psoriasis quality of life index (PQOL), Psoriasis Disability (PDI) and acceptance of psoriasis scale index (PAI) were measured using Arabic validated tools. Multivariate linear regression analysis was done to find out the independent predictors of the outcome variables.<br /> <strong>Results:</strong> The mean overall PQOL, PDI and PAI were 14.3, 20.8 and 60.1; respectively. Compared to the moderate/severe chronic plaque psoriasis, the mild chronic plaque shows significantly lower mean PQOL, lower mean PDI and higher mean PAI. There are positive moderate significant correlations between PQOL and PDI and PASI (r=0.59, r=0.54; respectively). However, there is inverse moderate significant correlation between PQOL and psoriasis acceptance index (r=-0.55). <br /> The linear regression revealed that the independent predictors of psoriasis quality of life are PDI, PASI and PAI. These three variables predict 0.42 of variability of PQOL. <br /> <strong>Conclusion:</strong> psoriasis exerts significant, negative effect on patients' quality of life. Disease disability, severity and its acceptance are independent predictors of quality of life.
Area Severity Index,Disability,Egypt
https://www.iranjd.ir/article_111545.html
https://www.iranjd.ir/article_111545_5293966fd964a0bf21629181b1308a7f.pdf
Iranian Society of Dermatology
Iranian Journal of Dermatology
2717-0721
23
3
2020
10
01
Safety and efficacy of fluoxetine in the treatment of acne excoriée: a double-blind, placebo-controlled study
98
104
EN
Balakrishna P
Nikam
Department of Dermatology, Krishna
Institute of Medical Sciences, Karad
(Maharashtra), India
mangeshnikam@yahoo.com
Mohan
Kale
Department of Dermatology, Krishna
Institute of Medical Sciences, Karad
(Maharashtra), India
kims.submission@gmail.com
Varsha
Jamale
Department of Dermatology, Krishna
Institute of Medical Sciences, Karad
(Maharashtra), India
jamalevarsha@gmail.com
Tunika
Arora
Department of Dermatology, Krishna
Institute of Medical Sciences, Karad
(Maharashtra), India
Asma
Hussain
Department of Dermatology, Krishna
Institute of Medical Sciences, Karad
(Maharashtra), India
drasmaarif.5aug@gmail.com
Nishchhal
Shrivastav
Department of Dermatology, Krishna
Institute of Medical Sciences, Karad
(Maharashtra), India
nishchhal.pg@gmail.com
10.22034/ijd.2020.111546
<strong><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US;">Background</span></strong><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US;">: Self-inflicted acne excoriée is often observed in patients with compulsive skin picking, posing a challenge for diagnosis and treatment as the exact psychiatric cause remains unknown. Studies have suggested that <span style="color: #231f20;">serotonin reuptake inhibitors </span>such as fluoxetine may help in the management of this condition. To determine the efficacy and safety profile of fluoxetine in the treatment of acne excoriée and to study the psychological profiles of patients.</span><br /> <strong><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US;">Methods:</span></strong><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US;"> Sixty patients of either sex aged ≥16 years with acne excoriée </span><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US; mso-bidi-language: EN-US;">were assigned to either Group A (n=30), which received oral fluoxetine (F) (20 mg/day) and oral doxycycline (D) (100 mg/day) with topical clindamycin (1%), or Group B (n=30), which received a placebo (P), oral doxycycline (100 mg/day), and topical clindamycin (1%). Patients were evaluated for standardized rating scales and followed up every two weeks for 12 weeks.</span><br /> Results: <span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US; font-weight: normal; mso-bidi-font-weight: bold;">Female gender predominance was observed in both groups, with most patients exhibiting anxiety and depression. With each follow-up visit (2<sup>nd</sup>, 3<sup>rd</sup>, 4<sup>th</sup>, and 5<sup>th</sup>) in both groups (A and B), the mean AESI (91.4% vs. 26.7%), HAM-A (80% vs. 27.7%), MADRS (68.1% vs. 28.2%), YBOCS (98.27% vs. 15.63%), PGA (88.47% vs. 31.38%), and VAS (99.17% vs. 37.67%) scores decreased from baseline by the final visit, indicating improved patient conditions. Significant differences were observed between the two groups (p <0.001) in the overall response, indicating that fluoxetine was more efficacious than the control. No remarkable side effects were noted. </span><br /> <br /> Conclusion: <span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US; font-weight: normal; mso-bidi-font-weight: bold;">Fluoxetine efficiently managed acne excoriée without remarkable side effects.</span><br /> <strong><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US;">Background</span></strong><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US;">: Self-inflicted acne excoriée is often observed in patients with compulsive skin picking, posing a challenge for diagnosis and treatment as the exact psychiatric cause remains unknown. Studies have suggested that <span style="color: #231f20;">serotonin reuptake inhibitors </span>such as fluoxetine may help in the management of this condition. <span style="mso-bidi-font-weight: bold;">To determine the efficacy and safety profile of fluoxetine in the treatment of acne excoriée and to study the psychological profiles of patients.</span></span><br /> <strong><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US;">Methods:</span></strong><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US;"> Sixty patients of either sex aged ≥16 years with acne excoriée </span><span style="mso-bookmark: _Hlk32225533;"><span style="mso-bidi-font-size: 12.0pt; line-height: 150%; mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: major-bidi; mso-ansi-language: EN-US; mso-bidi-language: EN-US;">were assigned to either Group A (n=30), which received oral fluoxetine (F) (20 mg/day) and oral doxycycline (D) (100 mg/day) with topical clindamycin (1%), or Group B (n=30), which received a placebo (P), oral doxycycline (100 mg/day), and topical clindamycin (1%). Patients were evaluated for standardized rating scales and followed up every two weeks for 12 weeks.</span></span><br /> <span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US;">Results: </span><span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US; font-weight: normal; mso-bidi-font-weight: bold;">Female gender predominance was observed in both groups, with most patients exhibiting anxiety and depression. With each follow-up visit (2<sup>nd</sup>, 3<sup>rd</sup>, 4<sup>th</sup>, and 5<sup>th</sup>) in both groups (A and B), the mean AESI (91.4% vs. 26.7%), HAM-A (80% vs. 27.7%), MADRS (68.1% vs. 28.2%), YBOCS (98.27% vs. 15.63%), PGA (88.47% vs. 31.38%), and VAS (99.17% vs. 37.67%) scores decreased from baseline by the final visit, indicating improved patient conditions. Significant differences were observed between the two groups (p <0.001) in the overall response, indicating that fluoxetine was more efficacious than the control. No remarkable side effects were noted. </span><br /> <span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US;">Conclusion: </span><span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US; font-weight: normal; mso-bidi-font-weight: bold;">Fluoxetine efficiently managed acne excoriée without remarkable side effects.</span><br /> <span style="mso-ansi-language: EN-US;"> </span><br /> <span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US;">Keywords: </span><span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US; font-weight: normal; mso-bidi-font-weight: bold;">acne</span><span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; font-weight: normal; mso-bidi-font-weight: bold;" lang="EN-GB">vulgaris</span><span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US; font-weight: normal; mso-bidi-font-weight: bold;">,</span><span style="mso-ascii-font-family: 'Times New Roman'; mso-ascii-theme-font: major-bidi; mso-hansi-font-family: 'Times New Roman'; mso-hansi-theme-font: major-bidi; mso-ansi-language: EN-US; font-weight: normal; mso-bidi-font-weight: bold;">fluoxetine, doxycycline</span><br />
Acne Vulgaris,fluoxetine,Doxycycline
https://www.iranjd.ir/article_111546.html
https://www.iranjd.ir/article_111546_33abf72dc67c17db2ae92b5bbabf79eb.pdf
Iranian Society of Dermatology
Iranian Journal of Dermatology
2717-0721
23
3
2020
10
01
Clinical and epidemiological profile of psoriasis patients: a retrospective study in tertiary medical centers, Mangalore, India
105
111
EN
Nitin
Joseph
Kasturba Medical College, Light
House Hill Road, Mangalore,
Manipal Academy of Higher
Education, Manipal, India
drnitinjoseph@gmail.com
Deepti
D’Souza
Department of Dermatology, Kasturba Medical College Hospital,
Attavar, Mangalore, Manipal
Academy of Higher Education,
Manipal, India
deepti.dsouza@manipal.edu
Matthew
Antony
Manoj
Kasturba Medical College, Light
House Hill Road, Mangalore,
Manipal Academy of Higher
Education, Manipal, India
matthewmanoj12@gmail.com
Shajimon
Priya
Varsha
Kasturba Medical College, Light
House Hill Road, Mangalore,
Manipal Academy of Higher
Education, Manipal, India
shaji196909@hotmail.com
Tanya
Singh
Kasturba Medical College, Light House Hill Road, Mangalore, Manipal Academy of Higher Education, Manipal, India
singhtanya495@gmail.com
Archit
Gupta
Kasturba Medical College, Light House Hill Road, Mangalore, Manipal Academy of Higher Education, Manipal, India
archit.gupta96@gmail.com
Akshiti
Kaushik
Kasturba Medical College, Light House Hill Road, Mangalore, Manipal Academy of Higher Education, Manipal, India
akshitikaushik@gmail.com
10.22034/ijd.2020.111547
<strong>Background:</strong> Psoriasis is an immune-mediated chronic skin disorder. Information regarding its clinic-epidemiological manifestations is limited in parts of Asia. This study was conducted to determine the risk factors, clinical presentation, and management of psoriasis among patients in Mangalore, India.<br /> <strong>Methods:</strong> The medical records of 225 psoriasis patients over the past ten years (from January 2009 till March 2019) were examined by the investigators. Data were collected using a semi-structured form.<br /> <strong>Results:</strong> The mean age at diagnosis of psoriasis was 42.2 ± 16.0 years. Nail psoriasis and psoriatic arthritis (PsA) were present in 66 (29.3%) and 21 (9.3%) patients, respectively. Relapse of psoriasis was seen more among patients with a history of disease exacerbation in winter (P=0.009) or in rainy seasons (P=0.031). Systemic therapy with methotrexate and topical therapy with steroids were used in the management of 52 (23.1%) and 72 (32%) patients, respectively. Phototherapy (n=11) was the most common modality used among the 18 patients with extensive psoriasis. Co-morbidities like diabetes mellitus (P=0.02) and complications like PsA (P=0.008) were associated with greater disease durations among the patients.<br /> <strong>Conclusion:</strong> The proportion of patients with extensive psoriasis was high in the current setting probably because of delayed diagnosis. Awareness about the disease and its clinical manifestations might help in its early identification. Seasonal exacerbation was an important risk factor for psoriasis and it was associated with its relapse. The most common management modalities were topical steroids for psoriasis and phototherapy for extensive psoriasis.<br /> <br /> <strong> </strong>
Psoriasis,risk factors,psoriatic arthritis
https://www.iranjd.ir/article_111547.html
https://www.iranjd.ir/article_111547_fcf23b540caa2c08d80aea97f58ae1c7.pdf
Iranian Society of Dermatology
Iranian Journal of Dermatology
2717-0721
23
3
2020
10
01
Frontal fibrosing alopecia: a clinicopathological study of 22 cases from Shiraz, Southern Iran
112
119
EN
Fatemeh
Sari Aslani
0000-0002-6232-9923
Molecular Dermatology Research
Center, Shiraz University of Medical
Sciences, Shiraz, Iran
sari_aslani_f@yahoo.com
Nasrin
Saki
0000-0002-9795-6898
Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
nasrinsa85@yahoo.com
Mohammad
Sasannia
0000-0002-1179-8869
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
mohammadsasannia@gmail.com
10.22034/ijd.2020.111548
<strong>Background: </strong>Since its recognition, frontal fibrosing alopecia (FFA) has increasingly been studied globally in terms of its diverse aspects. Having found no studies describing this condition in Southern Iran, we examined the different clinicopathological features of patients with FFA who referred to Faghihi Hospital, Southern Iran, between 2013 and 2018.<br /> <strong>Methods: </strong>We searched the archives of the Pathology Department of Faghihi Hospital for the cases with a diagnosis of FFA. Due to its similar histopathologic features with lichen planopilaris, the final diagnosis was made using clinical correlations.<br /> <strong>Results: </strong>Twenty-two patients were enrolled; all were female. Fifteen (68.2%) presented with the disease before menopause. Besides frontal and/or temporal hairline involvement in all the patients, eyebrow alopecia, eyelash loss, body hair loss, and facial papules were present in 81.8%, 27.3%, 50%, and 68.2% of them, respectively. Dermoscopic findings included follicular opening loss (100%), honeycombing of the scalp (81.8%), multiple white dots (77.3%), perifollicular erythema (63.6%), and perifollicular scales (59.1%). The histopathologic examination revealed follicular dropout (95.4%), perifollicular lymphocytic infiltration in the infundibulum and isthmus of the follicles (81.8%), perifollicular fibroplasia (77.3%), intact interfollicular epidermis (59.1%), mild perivascular lymphocytic infiltration in the upper dermis (54.5%), and apoptotic keratinocytes in the infundibulum and isthmus (50%). The most common comorbidity was hypothyroidism (40.9%).<br /> <strong>Conclusions: </strong>Thediagnosis of FFA should be considered in both premenopausal and postmenopausal women. Eyebrow alopecia, eyelash loss, body hair involvement, and facial papules are helpful clues in the diagnosis. The coexistence of hypothyroidism with FFA suggests immunological involvement in the pathogenesis.<br />
hair,Lichen Planus,eyebrows,Dermoscopy,Pathology
https://www.iranjd.ir/article_111548.html
https://www.iranjd.ir/article_111548_a43492418e415d187a10994c4c655ba2.pdf
Iranian Society of Dermatology
Iranian Journal of Dermatology
2717-0721
23
3
2020
10
01
Multidrug resistant Candida glabrata in an oral lichen planus patient
120
124
EN
Ensieh
Lotfali
0000000167091320
Department of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
ensiehlotfali@yahoo.com
Alireza
Firooz
0000-0001-7274-4840
Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences
alifiruz@yahoo.com
Azam
Fattahi
Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran
fattahiazam.mycologist@gmail.com
Mojgan
Borzouie
Medical laboratory scientist, Hospital Romgermed, Bucharest, Romania
immuneleana@gmail.com
Behzad
Chalaki
Student Research Committee, Gifted and Talented Dental Students Division, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
behzadchalaki@gmail.com
Reza
Ghasemi
Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
rezaghasemi190@gmail.com
Mohammad Mahdi
Rabiei
Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
m.mahdi.rabiei@gmail.com
Sareh
Farhadi
Assistant professor, Oral &Maxillofacial pathology dept, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
dr.sfarhadi@gmail.com
Seyed Amirfarshad
Esteghamat
Student Research Committee, Gifted and Talented Dental Students Division, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
arshad.esteghamat@gmail.com
Mobina
Habibollahi
Student Research Committee, Gifted and Talented Dental Students Division, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
mobina_mh97@yahoo.com
10.22034/ijd.2020.111551
Oral lichen planus (OLP) is a mucocutaneous disease characterized by inflammation leading to severe damage to the epithelial basal layer. This report describes a case of a 65-year-old Iranian female with a complaint of multifocal white lesions on the buccal and tongue mucosa with a reticular pattern and a focal pseudomembranous appearance (similar to thrush), together with burning symptoms for fourteen months. The patient was using topical fluocinolone acetonide 0.1%, two to three times a day at least for six months to control the ulcers and erythema. Molecular analysis of the thrush sample revealed <em>Candida glabrata</em> as the causative agent. Histopathologic examination confirmed the diagnosis of OLP. The minimum inhibitory concentration analysis was performed according to CLSI-M60 and revealed that this <em>C. glabrata</em> isolate was multidrug-resistant (resistant to nystatin, fluconazole, micafungin, and caspofungin). Finally, this patient was treated with amphotericin B oral suspension (0.5 g/5 ml) thrice daily for 14 days. The thrush disappeared completely and the patient no longer had any pain or burning sensations. <em>Candida glabrata</em>, the second most common cause of candidemia, is a major opportunistic fungal pathogen of humans that causes systemic as well as, mucosal and superficial infections. This case is the first case of OLP accompanied by multidrug-resistant <em>C. glabrata</em>.
Oral lichen planus, Candida glabrata, multidrug resistance
https://www.iranjd.ir/article_111551.html
https://www.iranjd.ir/article_111551_34cd32f9d383fa996a8dc19471c90ff7.pdf
Iranian Society of Dermatology
Iranian Journal of Dermatology
2717-0721
23
3
2020
10
01
Lichen planus pigmentosus successfully treated with conventional CO2 laser resurfacing
125
128
EN
Ramin
Radmanesh
Radmanesh Dermatologic and Laser Center, Tehran, Iran
r.radmanesh@gmail.com
Mohammad
Radmanesh
Radmanesh Dermatologic and Laser Center, Tehran, Iran
radmanesh_m@yahoo.com
10.22034/ijd.2020.111552
Lichen planus pigmentosus (LPP) develops as an asymptomatic and dusky pigmentation of the facial skin with no effective treatment. Herein we report a 54-year-old lady with clinical and histopathologic confirmation of LPP who was scheduled to be treated with CO2 laser resurfacing. After tumescent anesthesia, the whole facial skin was treated with three passes of Ultrapulse conventional CO2 ablation. The energy used in the first, second, and third passes were 6.6, 5.4, and 4.8 mJ, respectively. The mandibular area was treated with two passes (4.2 and 3.6 mJ). The eye contours were treated with two passes (3.9 and 3.3 mJ). The patient’s face remained edematous for a week, with the facial skin oozing within the first three days before it became crusted. The crust shed out from day three to six. After a week, smooth and erythematous skin appeared. The erythema persisted for up to four months, after which uniform skin with considerable bleaching and rejuvenation developed. No recurrence occurred within 18 months of follow-up. We conclude that LPP can be treated with CO2 laser resurfacing without any complications.
Lichen Planus,CO2 laser,treatment
https://www.iranjd.ir/article_111552.html
https://www.iranjd.ir/article_111552_d9b347926fb4e39c0a1a2e3fe325e2ff.pdf
Iranian Society of Dermatology
Iranian Journal of Dermatology
2717-0721
23
3
2020
10
01
Cutaneous reaction to the first dosage of Japanese encephalitis vaccine: a letter to editor
129
130
EN
Beuy
Joob
Private Clinic, Bangkok Thailand
beuyjoob@hotmail.com
Viroj
Wiwanitkit
0000-0003-1039-3728
Department of Community Medicine, Dr DY Patil
University, Pune, India
wviroj@yahoo.com
10.22034/ijd.2020.111550
cutaneous,reaction,Japanese Encephalitis,Vaccine
https://www.iranjd.ir/article_111550.html
https://www.iranjd.ir/article_111550_127cc89fa96b894aa4699b74c512326c.pdf