TY - JOUR ID - 101094 TI - A comparative study on the efficacy of intralesional injections of Bleomycin and Normal Saline in treatment of recalcitrant common warts on palm and dorsum of hand JO - Iranian Journal of Dermatology JA - IJD LA - en SN - AU - Yazdanfar, A AU - Karimirad, K AU - Mani Kashani, Kh AD - Y1 - 2003 PY - 2003 VL - 7 IS - 1 SP - 8 EP - 13 KW - Yazdanfar A KW - Karimirad K KW - Mani Kashani Kh DO - N2 - Background: Wart is a common skin disease, and 8% of patients referred to dermatologists suffer from warts. Objective: To compare the efficacy of intralesional injections of bleomycin with normal saline in treatment of common resistant warts on palms and dorsum of hands. Patients & Methods: This study was a double blind, randomized, controlled clinical trial on 34 patients with common warts on palms and dorsum of their hands. These patients were randomly divided into two groups: 18 patients were treated with intralesional injections of bleomycin and 16 patients were treated with intralesional injections of normal saline. After 3 weeks of treatment, patients were evaluated and in case of unresponsiveness the second injection with the same medication was attempted. This group was visited again 3 weeks later and finally response to treatment ad possible complications were evaluated. Results: In bleomycin group 88.9% and in normal saline group 56.3% remitted (Fisher’s exact test, P<0.05). Conclusion: Intralesional bleomycin is an effective and low risk treatment of common resistant warts on palms and dorsum of hands. UR - https://www.iranjd.ir/article_101094.html L1 - https://www.iranjd.ir/article_101094_4ea82f5a55e72ed11962687a66af7105.pdf ER -