TY - JOUR ID - 98069 TI - The Comparison of Oral Ivermectin and Topical Lindane in the Treatment of Scabies JO - Iranian Journal of Dermatology JA - IJD LA - en SN - AU - Mohammad Ali, Mapar AU - Behrooz, Mali AD - Y1 - 2008 PY - 2008 VL - 11 IS - 4 SP - 147 EP - 150 KW - antiscabietics KW - Ivermectin KW - Lindane DO - N2 - Background: Scabies is a common skin disease and a public health problem. The topical antiscabietics have a poor compliance. The aim of this study was to compare the efficacy of oral Ivermectin with topical Lindane solution in the treatment of scabies. Methods: This was a prospective comparative open study. Fifty seven patients were randomized in two groups. One group (32 patients) received 200µg/kg body weight of Ivermectin in two oral doses with a one-week interval, and the second group, (25 patients) received 2 consecutive weekly topical applications of Lindane. All patients were followed up for 2 weeks. Results: A single oral dose of Ivermectin cured 72% of patients and 91% of the patients were cured after the second dose. Two applications of Lindane with a one-week interval cured 92% of cases. Conclusion: Compared to topical Lindane in the treatment of scabies, Ivermectin was at least as effective as Lindane. UR - https://www.iranjd.ir/article_98069.html L1 - https://www.iranjd.ir/article_98069_28e152ac110fa54f03038ee8d9532948.pdf ER -