Document Type : Case Report
Authors
Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India
Abstract
Porokeratosis is a heterogeneous group of keratinization disorders
with an autosomal dominant inheritance pattern. The etiology and
pathogenesis of this disease have not been completely elucidated.
The porokeratosis clinically presents with a characteristic prominent
peripheral ridge and central dell. The histological feature of the
parakeratotic column known as ‘cornoid lamellae’ is a hallmark
feature observed in the peripheral rim. Among the various
morphological forms, linear porokeratosis is a rare variant with
four subtypes. When compared to other forms, the linear variant
carries an increased risk of malignancy, particularly squamous
cell carcinoma, warranting a regular follow-up. Though there are
multiple treatment options, achieving complete clinical resolution
is difficult. We report an interesting case of linear porokeratosis
with generalized lesions in a 60-year-old male. The lesions were
typical and predominantly distributed in the extremities. The
biopsy was diagnostic in our patient. This case is reported for
its rare presentation and clinical interest.
Keywords
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