Laser– assisted permanent hair removal iscommonly performed for the treatment of unwantedhair. This procedure is usually associated withpain and pain reduction has an important role inthe success of this treatment. A common methodof reducing pain is to use topical analgesics . Amixture of lidocaine and prilocaine (EMLA) is acommonly used and very effective topical anesthetic.Another agent is diclofenac gel. Diclofenac is anon-steroidal anti-inflammatory drug (NSAID) andis a potent inhibitor of inducible cyclo-oxygenase(COX-2) . Oral administration of this medicationcan result in adverse effects. There are no studieson its efficacy as a topical anesthetic in laser hairremoval.