Khalili Maryam; Farajzadeh Saeedeh; Mohammadi Saman; Aflatoonian Mahin; Ahmadi Rahim; Zeinadini Alireza
Abstract
Leishmaniasis is a common parasitic disease classified to acute and chronic types based on the duration of the disease. The acute lesion is presented as ulcerated papule and nodule that heal after a few months with an atrophic scar. The chronic form of cutaneous leishmaniasis is a nonhealing lesion that ...
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Leishmaniasis is a common parasitic disease classified to acute and chronic types based on the duration of the disease. The acute lesion is presented as ulcerated papule and nodule that heal after a few months with an atrophic scar. The chronic form of cutaneous leishmaniasis is a nonhealing lesion that is persistent for more than one year. Here, we describe a chronic case of leishmaniasis developed after a head injury, similar to a keloidal scar.
Mohammadi Saman; Khalili Maryam; Fadai Fahameh; Badakhsh Hoda; Farajzadeh Saeedeh; Mohebbi Azadeh; Aflatoonian Mahin
Volume 20, Issue 4 , 2017, , Pages 131-134
Abstract
Goltz syndrome or focal dermal hypoplasia is a rare syndrome with mesoectodermal hypoplasia. This syndrome is an X-linked dominant disorder with involvement of the cutaneous, ocular, dental and skeletal systems. The most significant feature of this disease is connective tissue dysplasia. Here, we report ...
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Goltz syndrome or focal dermal hypoplasia is a rare syndrome with mesoectodermal hypoplasia. This syndrome is an X-linked dominant disorder with involvement of the cutaneous, ocular, dental and skeletal systems. The most significant feature of this disease is connective tissue dysplasia. Here, we report a 30-year old woman who presented with congenital unilateral linear atrophic areas on her trunk, back, and upper and lower extremit
Farajzadeh Saeedeh; Esfandiarpour Iraj; Abbassi Mohammad Mehdi Hayatbatch; Moghaddam Sodaif Darvish; Hosseininasab Fatemeh
Volume 13, Issue 3 , 2010, , Pages 78-81
Abstract
Background: The correlation between coronary artery disease and androgenic alopecia has been demonstrated, but the mechanism of this association still remains to be cleared. Objective: To investigate lipid profile, as an indicator of coronary artery disease, in women with female pattern alopecia. Methods: ...
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Background: The correlation between coronary artery disease and androgenic alopecia has been demonstrated, but the mechanism of this association still remains to be cleared. Objective: To investigate lipid profile, as an indicator of coronary artery disease, in women with female pattern alopecia. Methods: Fifty one women with female pattern alopecia and thirty one healthy women with normal hair status were selected as the case and control groups, respectively. Lipid profile including cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, lipoprotein (a), apolipoprotein A1, and apolipoprotein B were measured in both groups. Results: The most important result of our study was a remarkably higher level of lipoprotein (a) in the case group. On the other hand, 55.3% of the patients and 16.7 % of the controls had lipoprotein (a) level >30 mg/dl, higher than the critical level for atherosclerosis. Conclusion: Lipid profile, especially lipoprotein (a), which is an important risk factor for coronary artery disease, should be investigated in women with androgenic alopecia. Those with disturbance in lipid profile should be referred to a cardiologist.
Farajzadeh Saeedeh; Bazargan Nasrin; Shahesmaeili Armita; Shahrbabaki Azam Gholami; Fekri Ali Reza
Volume 13, Issue 2 , 2010, , Pages 33-36
Abstract
Background: The role of food allergy in atopic dermatitis (AD) is controversial. The aim of this study was to determine the frequency of food allergens in children with AD. Method: Fifty one atopic dermatitis children aged 6 months to 5 years entered our study. The severity of AD was determined by scoring ...
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Background: The role of food allergy in atopic dermatitis (AD) is controversial. The aim of this study was to determine the frequency of food allergens in children with AD. Method: Fifty one atopic dermatitis children aged 6 months to 5 years entered our study. The severity of AD was determined by scoring index of AD (SCORAD). Skin prick test (SPT) was done using 15 allergens including the white of the egg, yolk, peanut, kiwi, strawberry, cow's milk, walnut, fish, banana, wheat, orange, tomato, cereals, apple and cocoa. Results: Thirty four patients (66.7%) had a positive reaction to one or more allergens and in 17 patients (33.3%), the SPT was negative to all allergens. Eleven patients (21.6%) had a positive SPT to one food allergen, 9 patients (17.6%) to two allergens, 9 patients (17.6%) to three allergens, 3 patients (5.9%) to four allergens, 1 patient (2%) to seven allergens and 1 patient (%2) to ten allergens. The most common food allergen among 15 allergens was white egg in 19 patients (37.3%). Yolk was the second most common allergen in 11 patients (21.6%). The relationship between the severity of the SPT with AD severity was observed only for cow's milk, which showed a reverse relationship (R=-0.337). Conclusion: White egg was the most common allergen in all ages and both sexes. Food allergens may play a role in the pathogenesis of atopic dermatitis.
Yazdi Simin Sar; Farajzadeh Saeedeh; Abadi Ali Zeinali Hossein
Volume 13, Issue 2 , 2010, , Pages 54-56
Abstract
Introduction: Various factors are involved in the pathogenesis of acne vulgaris. Recently, G6PD deficiency has been proposed in the pathogenesis of acne. G6PD has an important role in the oxidant/antioxidant balance. According to this theory, antioxidants are used in the treatment of acne recently. The ...
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Introduction: Various factors are involved in the pathogenesis of acne vulgaris. Recently, G6PD deficiency has been proposed in the pathogenesis of acne. G6PD has an important role in the oxidant/antioxidant balance. According to this theory, antioxidants are used in the treatment of acne recently. The aim of this study was to evaluate G6PD deficiency in patient with acne vulgaris. Methods: The activity of G6PD enzyme was measured in the venous blood of 82 patients with acne vulgaris of different severity. The fluorescent lamp method was used in order to determine the activity of G6PD enzyme. Results: The mean age of the patients was 25± 3. From 82 patients, the level of the G6PD enzyme was normal in 77 (93.9%) patients. Also, 4 (4.9%) patients had relative G6PD deficiency and 1 (1.2%) patient had severe G6PD deficiency. As the incidence of G6PD deficiency is 5.7% in the normal population, there was no statistically significant difference in G6PD deficiency between patients and the normal population. No significant relationship was found between acne severity and G6PD deficiency. Conclusion: In order to detect the association between acne and G6PD deficiency, other case-control studies with lager sample sizes are recommended.
Ayatolahi Seyed Amin Mossavi-; Farajzadeh Saeedeh; Fekri Ali Reza; Vares Behrooz; Fekri Sahba
Volume 12, Suppl.3 , 2009, , Pages 12-15
Abstract
We describe a 31-year-old man, a known case of hepatitis C infection for 11 years, who presented with a chronic non-healing large deep ulcer on the dorsum of the right foot for five months. Fusarium solani infection was confirmed by skin biopsy and culture. The biopsy specimen showed an unusually extensive ...
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We describe a 31-year-old man, a known case of hepatitis C infection for 11 years, who presented with a chronic non-healing large deep ulcer on the dorsum of the right foot for five months. Fusarium solani infection was confirmed by skin biopsy and culture. The biopsy specimen showed an unusually extensive dermal invasion with fungal hyphae. The patient's response to oral itraconazole 100 mg/day for 3 months was excellent. Closed monitoring of liver enzymes was done before and during the treatment course.
Farajzadeh Saeedeh; Zandi Soodabeh; Vares Behrooz; Sharifzadeh Mahdiyeh; Fekri Ali-Reza
Volume 11, Issue 1 , 2008, , Pages 21-24
Abstract
Background: Atopic dermatitis is the most common chronic inflammatory dermatitis, due to immunological disorders. Patients with atopic dermatitis are prone to infectious diseases including bacterial infections. On the other hand, atopy may be protective against helminthes parasites. The objective of ...
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Background: Atopic dermatitis is the most common chronic inflammatory dermatitis, due to immunological disorders. Patients with atopic dermatitis are prone to infectious diseases including bacterial infections. On the other hand, atopy may be protective against helminthes parasites. The objective of this study was to compare the frequency and clinical presentations of cutaneous leishmaniasis in atopic dermatitis patients with the control group in an outpatient clinic in Kerman.Methods: This was a case – control study done on 459 patients with atopic dermatitis, who were diagnosed based on Hanifin & Rajka criteria and 400 healthy subjects without immunosuppression as our control group. The frequency of leishmaniasis was investigated in both groups according to age, gender and residential area.Results: Among 459 atopic dermatitis patients, 232 were female and 227 were male. Control group consisted of 232 males and 168 females. The mean age of the atopic dermatitis patients and the controls was 9.2 and 13.3 years, respectively (p0.05%). There was no statistically significant difference in clinical presentations of leishmaniasis between two groups.Conclusion: In this study there was no significant relationship between leishmaniasis and atopic dermatitis. This finding can be due to the small sample size or the difference between case and control groups regarding age.
