Jahangir Majid; Qayoom Seema; Peerzada Sajad; Naseer Choh; Rifat Ara; Kafeel Khan
Volume 18, Issue 1 , 2015, , Pages 1-5
Abstract
Background: Hirsutism, a common clinical condition, not onlycauses cosmetic concern but may also be a sign of underlyingdisease. Polycystic ovary syndrome (PCOS) is an importantand common cause of hirsutism. In fact, many women withPCOS present as hirsutism. This study assessed young Kashmiriwomen presenting ...
Read More
Background: Hirsutism, a common clinical condition, not onlycauses cosmetic concern but may also be a sign of underlyingdisease. Polycystic ovary syndrome (PCOS) is an importantand common cause of hirsutism. In fact, many women withPCOS present as hirsutism. This study assessed young Kashmiriwomen presenting as hirsutism, for ultrasonographic evidence ofpolycystic ovaries (PCO), in addition to recording their clinical andhormonal profile. The purpose of this study was to determine theprevalence of polycystic ovary syndrome using ultrasonography,in young Kashmiri women presenting as hirsutism.Method: In total, one hundred and seventy (170) consecutive youngKashmiri women presenting with chief complaint of hirsutismwere assessed. A total of eighty (80) age matched non- hirsutefemales having normal menstrual cycles, served as controls. Theovaries were visualised by transabdominal ultrasonography (USG).The serum was analysed for luteinizing hormone (LH), folliclestimulating hormone (FSH), total testosterone (tT), prolactin(PRL) and thyroid stimulating hormone (TSH).Result: The study showed prevalence of 61.18% PCOS in youngKashmiri women presenting as hirsutism. PCOS was diagnosed in35.11% hirsute women with regular menses and ultrasonographywas used to identify PCO in 90.35% patients. Biochemicalhyperandrogenemia was present in 70.15% of the patients andthe LH/FSH ratio increased in 81.73% of the patients.Conclusion: The results of this study show a high prevalence ofPCOS in young Kashmiri women presenting as hirsutism andalso highlights the fact that PCOS is not necessarily associatedwith menstrual disturbances. Therefore, all hirsute women, evenwith regular menses, should be evaluated for PCOS.
Hassan Iffat; Sajad Peerzada; Jahangir Majid
Volume 15, Issue 2 , 2012, , Pages 47-49
Abstract
Background: Systemic sclerosis is an autoimmune connective tissue disorder which is characterised by cutaneous and internal organ fibrosis. Raynaud’s phenomenon is the earliest feature and may precede the onset of the disease by months to years. The heart, lungs, gastrointestinal tract, kidneys ...
Read More
Background: Systemic sclerosis is an autoimmune connective tissue disorder which is characterised by cutaneous and internal organ fibrosis. Raynaud’s phenomenon is the earliest feature and may precede the onset of the disease by months to years. The heart, lungs, gastrointestinal tract, kidneys and other organs may be involved. Our aim was to evaluate skin thickness and echogenicity in systemic sclerosis patients by ultrasound and compare it with the healthy age and sex matched controls. Method: Our study included 15 successively admitted patients (14 females and 1 male) with systemic sclerosis and 15 healthy age and sex matched controls. All the patients met the ACR criteria of diagnosis. The age range of the patients was 25-55 years. The disease duration ranged from 1-8 years. A complete history and physical examination was done for each patient. Skin thickness and echogenicity were measured by a 20MHz ultrasound probe at 6 different anatomical sites which was compared with that of the controls. Result: Skin thickness was more in systemic sclerosis patients (significant p value) as compared to controls, and echogenicity was inversely proportional to the skin thickness. Conclusion: Skin ultrasonography is a noninvasive method which can reflect the severity of skin involvement and periodic assessment of skin thickness and echogenicity can help to monitor the progression of the disease.