Fatemeh Mohaghegh; Ali Asilian; Soheila Taheri; Parvin Rajabi
Volume 12, Suppl.3 , 2009, , Pages 23-24
Abstract
Sebaceoma is a benign tumor with sebaceous differentiation. It usually presents as a yellowish papule or nodule on the face and scalp. This is a report of a 27-year-old-woman who presented with a giant, 6cm×4.5 cm exophytic tumor on her head. Clinically, we considered several diseases; however, ...
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Sebaceoma is a benign tumor with sebaceous differentiation. It usually presents as a yellowish papule or nodule on the face and scalp. This is a report of a 27-year-old-woman who presented with a giant, 6cm×4.5 cm exophytic tumor on her head. Clinically, we considered several diseases; however, the histological and immunohistochemical features matched those of sebaceoma. The lesion was excised and the defect was repaired by a split-thickness graft.
Soheila Taheri; Ali Asilian; Gita Faghihi
Volume 12, Issue 2 , 2009, , Pages 36-41
Abstract
Background: Many efforts are made to find new and more effective treatments for psoriasis. Intralesional 5-Fluorouracil (5-FU) +epinephrine is a cheap option which can be administered with long intervals. The effectiveness of Pulse Dye Laser (PDL) on psoriasis has been already assessed. We decided to ...
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Background: Many efforts are made to find new and more effective treatments for psoriasis. Intralesional 5-Fluorouracil (5-FU) +epinephrine is a cheap option which can be administered with long intervals. The effectiveness of Pulse Dye Laser (PDL) on psoriasis has been already assessed. We decided to evaluate the effectiveness of 5-FU+epinephrine and compare it to betamethasone and PDL.Methods: A group of 22 patients with chronic stable plaque psoriasis were included. Three plaques on each patient were treated with 5- FU+epinephrine, PDL and betamethasone, respectively. Psoriasis Severity Index (PSI) scoring was applied to assess each plaque before treatment and in weeks 2, 4, 6, 12, and 24. Photos of each plaque were taken before treatment and at each treatment and follow-up session. They were finally compared and scored by a dermatologist.Results: Decline in mean Psoriasis Severity Index (PSI) in week 6 (2 weeks after treatment) and in week 24 (the last follow-up session) was statistically significant as compared to baseline in all groups. (P<0.001) The highest decline in mean PSI score was in the 5-FU+epinephrine group while the lowest belonged to the PDL group (80% vs. 27%).The mean period of remission in the 5-FU+epinephrine group was significantly longer in comparison to the two other groups. (P<0.001) In photographic evaluation, the best response was observed in the 5- FU+epinephrine group.Conclusion: 5-FU+epinephrine is a cheap option which can provide a rapid response and long remission .With respect to limited effectiveness, short remission and high cost; PDL dose not seem to be a preferred choice in the treatment of psoriasis.
Fariba Iraji; Nader Arbaby; Ali Asilian; Amir Hossein Siadat; Jalal Keshavarz
Volume 9, Issue 4 , 2006, , Pages 331-134
Abstract
Background and aim: Non-melanoma skin cancers (NMSC) are one of the most prevalent malignancies of the human. Although the morality rate is not high for these cancers, they may cause high morbility for the patients. In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, ...
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Background and aim: Non-melanoma skin cancers (NMSC) are one of the most prevalent malignancies of the human. Although the morality rate is not high for these cancers, they may cause high morbility for the patients. In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, inappropriate use of sunscreen and cultural changes may increase the incidence of these cancers. The objective of this study was to determine NMSC in Isfahan.Materials and Methods: We used data of the cancer resistery center for performing this study and the incidence of NMSC per 100,000 papulation was determined.Results: Overall 1681 cases were registered. The incidence of NMSC was calculated to be 10.67/100,000 population. The most common site for BCC and SCC was middle face.Conclusion: NMSC incidence in Isfahan is lower than west countries although this incidence is 10.67/100,000 in a year. It means that 5-6 thousand cases of NMSC occur in Iran each year. We can prevent its morbidity and mortality by early correct diagnosis.