Volume 27 (2024)
Volume 26 (2023)
Volume 25 (2022)
Volume 24 (2021)
Volume 23 (2020)
Volume 22 (2019)
Volume 21 (2018)
Volume 20 (2017)
Volume 19 (2016)
Volume 18 (2015)
Volume 17 (2014)
Volume 16 (2013)
Volume 15 (2012)
Volume 14 (2011)
Volume 13 (2010)
Volume 12 (2009)
Volume 11 (2008)
Volume 10 (2007)
Volume 9 (2006)
Volume 8 (2005)
Volume 7 (2004)
Volume 6 (2002)
Volume 5 (2002)
Volume 4 (2000)
Volume 3 (1999)
Volume 2 (1998)
Volume 1 (1997)
Frequency of depression in patients with acne vulgaris treated with short-course low dose oral isotretinoin

Nasim Niknezhad; Behnaz Hamedani; Abbas Zamanian; Reza Mahmoud Robati; Elnaz Hamedani

Volume 23, Issue 4 , 2020, , Pages 150-154


  Introduction: Acne vulgaris affects individuals of all ages, and isotretinoin is the most effective treatment available for this disease. However, serious adverse effects, including the possibility of depression and suicide, could limit its use. This study aimed to investigate the ...  Read More

The effect of metformin in the treatment of intractable and late onset acne: a comparison with oral isotretinoin

Behrangi Elham; Sadeghi Somayeh; Sadeghzadeh-Bazargan Afsaneh; Goodarzi Azadeh; Ghassemi Mohammadreza; Sepasgozar Saba; Rohaninasab Masoomeh

Volume 22, Issue 2 , 2019, , Pages 47-52


  Background: Insulin resistance and increased insulin-like growth factor (IGF)-1 with consequent mammalian target of rapamycin complex (mTORC) 1 overexpression is responsible for acne pathogenesis, especially in women with polycystic ovary syndrome (PCOS). Metformin is shown to improve acne as an adjunct ...  Read More

Creatine phosphokinase values and myalgia during isotretinoin therapy

Ghiasi Maryam; Lajevardi Vahide; Mortazavi Hossein; Damavandi Maedeh Raiyati

Volume 16, Issue 4 , 2013, , Pages 137-140

  Background: Systemic isotretinoin is a very effective medication for the treatment of acne, but it has some side effects. One of its side effects is musculoskeletal problems such as increased levels of creatine phosphokinase (CPK), myalgia, and serious muscle damage such as rhabdomyolysis. The aim of ...  Read More

A review of three systemic retinoids in dermatology: acitretin, isotretinoin and bexarotene

Mortazavi Hossein; Aghazadeh Nessa; Ghiasi Maryam; Lajevardi Vahideh

Volume 16, Issue 4 , 2013, , Pages 144-158

  Retinoids are synthetic and natural analogues of vitamin A that have various effects on cellular differentiation, cellular proliferation, immune system, and embryonic development. The present study reviews the history of systemic retinoids in medicine, the structure of syn  Read More

Effects of Oral Isotretinoin on Serum Vitamin D Metabolites and Other Biochemical Markers of Bone Turnover and Calcium Homeostasis in Severe Acne

Hamideh Moravvej; Maryam Yousefi; Nahid Mohtasham; Nelda Saadat; Hamid Reza Haghighatkhah

Volume 11, Issue 3 , 2008, , Pages 108-112

  Background: Few studies have investigated on vitamin D metabolites Serum levels, and calcium homeostasis in humans receiving retinoids, despite a substantial amount of literature concerning retinoid-induced osteoporosis in animals. We prospectively measured vitamin D metabolites serum levels and calcium ...  Read More

Effects of Isotretinoin on bone density and Calcium homeostasis in patients with Acne Vulgaris

F Ghalamkar Pour; H Morravej Farshi; S Zolghadr

Volume 8, Issue 6 , 2006, , Pages 448-456

  Background and aim: Side effects of long-term systemic isotretinion use with high accumulative doses on skeletal system have been known, but there are few studies about the effects of short term isotretinoin therapy for acne patients. This study was aimed to recognize the effects of systemic isotretinion ...  Read More

Evaluation of the efficacy of intermittent Isotretinoin doses in Acne patients

P Toosi; A Sadiqha; H Monshi Zadeh; R Toosi

Volume 8, Issue 4 , 2005, , Pages 256-259

  Background and objective: Oral isotretinoin is the only treatment that has an effect on all the major etiological factors involved in acne (Increased sebum production, alterations in microbial flora, hyperkeratinization of pilosebaceous duct, and inflammation). Considering complications and relative ...  Read More