Armaghan Kazeminejad; Lotfollah Davoodi; Zohreh Hajheydari; Erfan Ghadirzadeh; Amirmasoud Taheri; Mohammad Ahmadi; Alireza Mozdastan
Abstract
Background and Method: Psoriasis is one of the most common skin diseases. For the first time in Iran, we conducted a case-control study to evaluate bone mineral density in patients with psoriasis vulgaris in comparison with a healthy control group (20 individuals in each group). Our study sample included ...
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Background and Method: Psoriasis is one of the most common skin diseases. For the first time in Iran, we conducted a case-control study to evaluate bone mineral density in patients with psoriasis vulgaris in comparison with a healthy control group (20 individuals in each group). Our study sample included patients referred to the dermatology clinic of Razi Hospital in Ghaemshahr, Iran, between May and October 2019. Densitometry was performed by the DEXA method on the 2nd to 4th lumbar vertebrae and hip bone. Patients’ demographic information and Psoriasis Area Severity Index (PASI) scores were recorded and analyzed using SPSS version 22.Results: The mean T-score in the case and control groups were -0.47 ± 1.04 and -0.19 ± 0.45, respectively (P = 0.274). The mean T-score had a significant inverse correlation with an age of 40 years or above (r = -0.873 and P < 0.001), disease duration of more than five years (r = -0.599, P = 0.05), and PASI score (r = -0.523, P = 0.001), but had a positive correlation with sunlight exposure (r = 0.581, P < 0.001).Conclusion: Considering the decrease in bone density in patients with psoriasis and its relationship with the disease severity and duration and the effectiveness of sunlight in increasing bone density, preventive treatment should be provided for all patients to increase bone density and prevent osteoporosis.
Ramin Taheri; Arash Nekuvaght Tak; Nooshin Masoudian
Abstract
Background: Psoriasis is a chronic and recurrent inflammatory skin disease. In some recent studies, the association between this disease and migraine headaches has been indicated. The present study aimed to determine the frequency of migraine headache in patients with psoriasis vulgaris.Methods: In this ...
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Background: Psoriasis is a chronic and recurrent inflammatory skin disease. In some recent studies, the association between this disease and migraine headaches has been indicated. The present study aimed to determine the frequency of migraine headache in patients with psoriasis vulgaris.Methods: In this cross-sectional study, 72 patients with psoriasis vulgaris referred to dermatologists in Semnan from April 2018 to September 2018 were included using the complete enumeration method. After the confirmation of migraine headache by a neurologist, the migraine severity and clinical features were assessed. Data were collected and analyzed by SPSS 16 software.Results: Among 72 patients with psoriasis vulgaris, 15 (20.8%) had a migraine. In patients with migraine headache compared to others, the mean and standard deviation of the visual analog scale-based headache severity (8.33 ± 1.05 vs. 4.11 ± 2.30, P < 0.001), MIDAS-based headache severity (13.85 ± 2.48 vs. 4.98 ± 2.11, P = 0.004), and PASI score-based psoriasis severity (22.55 ± 7.08 vs. 5.38 ± 2.95, P = 0.001) were significantly higher.Conclusion: The prevalence of migraine headaches is significantly higher in patients with psoriasis vulgaris, and patients with severe psoriasis are more likely to suffer from migraine headaches. We recommend screening for migraine headaches in patients with psoriasis, especially when the relevant risk factors are evident. High-risk patients should be given further consideration, facilitating the achievement of better management and higher patient satisfaction.
