Azadeh Goodarzi; Mahsa Farshidzadeh; Masoumeh Roohaninasab; Najmolsadat Atefi; Elham Behrangi
Abstract
Background: The use of vitamin D and its analogues in the treatment of warts has been to be effective and painless without any considerable side effects, unlike some other routine safe and effective therapeutic modalities such as cryotherapy that in some cases is really difficult ...
Read More
Background: The use of vitamin D and its analogues in the treatment of warts has been to be effective and painless without any considerable side effects, unlike some other routine safe and effective therapeutic modalities such as cryotherapy that in some cases is really difficult to perform due to related pain, especially in the children. Owing to a probable relationship between the deficiency of serum vitamin D and warts, this research aimed to find the association between level of serum vitamin D and warts. Methods: This case-control study was conducted on 56 subjects in Rasoul Akram Hospital, Tehran, Iran, for 18 months. The subjects were randomly divided into case and control groups, including 28 age and sex-matched subjects in each of them. The required data were extracted through a questionnaire. Finally, the data were analyzed in the SPSS software V.22 using tests such as Mann-Whitney and Pearson correlation. Results: In this study, 56 people were examined, and 28 subjects were included in both case and control groups. The mean serum level of vitamin D in both case and control groups was 23.564and 31.593, respectively. The association between serum levels of vitamin D in the group with and without wart was not significant in both men and female groups. Serum vitamin D levels were compared in two groups of under 18 years old and between 18 and 50 years old, which were not statistically significant. Conclusion: According to our results, there is no significant relationship between serum vitamin D levels and existence of warts. This relationship is not statistically significant at the level of age and sex variables, and there is no difference in age and gender between the case and control groups.
N Esmaeili; M Barzegari; M Rezaei
Volume 8, Issue 2 , 2005, , Pages 110-114
Abstract
Background: Lichen planus (LP) is an idiopathic papulosquamous disorder, which can show cutaneous or mucosal signs. It is caused by a cell mediated immune response to an antigen. A wide range of clinical manifestations has been reported. Objective: To determine the sex and age frequency and clinical ...
Read More
Background: Lichen planus (LP) is an idiopathic papulosquamous disorder, which can show cutaneous or mucosal signs. It is caused by a cell mediated immune response to an antigen. A wide range of clinical manifestations has been reported. Objective: To determine the sex and age frequency and clinical presentations of this disease in patients referred to Razi hospital in Tehran. Patients and Methods: In this observational case series study, patients referred to Razi hospital in Tehran from May to July 2003 were examined and clinically or clinicopathologically confirmed cases of LP were selected. Results: One-hundred and twenty patients had LP (52 females-68 males). The age range was 6-80 years and the mean age was 40.6 years. Sixty-seven of patients had cutaneous lesions, 20% had mucocutaneous and 13% had mucosal lesions. Hypertrophic LP was present in 22% and typical or classic LP was seen in 18%. Seven percent of patients had scalp involvement and oral LP was present in 33.3% of cases and the most common form was reticular. Genital lesions were present in 6% of cases mainly in male cases and as annular form. Six percent of patients had positive family history of LP. Conclusion: In this study LP was more common in male patients and in fourth decade of life. Hypertrophic LP and classic LP were the most common and reticular form was the most common form of oral LP. Genital lesions were mainly seen in male patients and as annular form.
