@article { author = {Zohreh, Tehranchinia and Hoda, Rahimi and Mohammad, Shahidi-Dadras and Ali, Farnaghi and Mahsa Seyed, Ahadi and Maral Seyed, Ahadi}, title = {Evaluation of the Primary Response of Basal Cell Carcinoma to Aminolevulinic Acid Photodynamic Therapy}, journal = {Iranian Journal of Dermatology}, volume = {13}, number = {3}, pages = {71-77}, year = {2010}, publisher = {Iranian Society of Dermatology}, issn = {2717-0721}, eissn = {2717-0721}, doi = {}, abstract = {Background: Basal Cell Carcinoma (BCC) is the most common type of skin cancer in human beings. Photodynamic therapy (PDT) is a novel therapeutic method which may be regarded as a non-invasive useful alternative for traditional treatments of BCC. This study was designed with the aim of evaluating the primary response of BCC to PDT.Methods: This clinical trial was performed on 28 BCC lesions. Patients were treated with ALA-PDT monthly for 1-6 sessions and evaluated for clinical response, cosmetic results and probable side effects.Results: Twenty three out of 28 lesions showed response to PDT (9 showed complete response and 14 showed partial response). The cosmetic result was excellent or good in 77.5% of the cases. In 92.8% of the cases, no or mild side effects were observed. Patients with a positive history of radiotherapy responded less (p<0.05). No significant relationship was found between patients' age, sex, localization, diameter or type of BCC with clinical response.Conclusion: PDT might be a good therapeutic option in the treatment of BCC, especially the superficial type, with high efficacy and few side effects.}, keywords = {Basal cell carcinoma,Photodynamic therapy,photo chemotherapy}, url = {https://www.iranjd.ir/article_98118.html}, eprint = {https://www.iranjd.ir/article_98118_8566825542ae399ccf4fd7c3d54c3147.pdf} }