%0 Journal Article %T Pretibial Epidermolysis Bullosa: Report of two cases %J Iranian Journal of Dermatology %I Iranian Society of Dermatology %Z 2717-0721 %A Yaghoobi, R %A Sina, N %A Emad Mostofi, N %A Rafiei, R %D 2004 %\ 12/01/2004 %V 8 %N suppl %P 39-46 %! Pretibial Epidermolysis Bullosa: Report of two cases %K Dystrophic epidermolysis bullosa %K Pretibial %K Albopapuloid lesions %K Anchoring fibrils %R %X Pretibial epidermolysis bullosa is a rare variant of hereditary epidermolysis bullosa characterized by the delayed onset of lesions and their localization. We present two cases, a 35-year-old woman and a 21-year-old man. They clinically had pruritus, nodular prurigo-like or lichenified lesions, violaceous scarring, milia, nail dystrophy and in one case albopapuloid lesions on the trunk. Physical signs of disease were first noticed between 3 and 9 years of age. Histologic examination showed a subepidermal blister with milia formation, and a mild mixed inflammatory infiltrate. These patients represent an nusual, poorly recognized form of dystrophic epidermolysis bullosa with features that resemble a variety of acquired dermatoses. %U https://www.iranjd.ir/article_98522_bd0634e2d10256fb97f67e41a0ce3771.pdf