%0 Journal Article %T Comparison of efficacy of oral Fluconazole with intramuscular Glucantime in patients with acute cutaneous Leishmaniasis %J Iranian Journal of Dermatology %I Iranian Society of Dermatology %Z 2717-0721 %A Famili, SZ %A Pezeshk Poor, F %A Sepehr, V %A Vahedian, M %D 2005 %\ 01/01/2005 %V 8 %N 2 %P 97-100 %! Comparison of efficacy of oral Fluconazole with intramuscular Glucantime in patients with acute cutaneous Leishmaniasis %K Cutaneous leishmaniasis %K Fluconazole %K glucantime %R %X Background: Cutaneous leishmaniasis is an important skin parasitic disease. Ideal treatment is not found yet and seeking for proper drugs continues. Objective: Comparison of the efficacy of fluconazole with systemic glucantime in patients with acute cutaneous leishmaniasis in Ghaem hospital in Mashhad in 2002. Patients and Methods: During one year of study, all patients with cutaneous leishmaniasis were divided to two group. Thirty-one patients were treated with oral fluconazole (100 mg twice a day) for 6 weeks and 29 patients were treated with intra-muscular glucantime (20 mgSb/kg) for 21 days. Both groups were evaluated 3 and 6 weeks after onset of treatment. T-test and Chi-square test were used for statistical analyses and (P0.05). Conclusion: It seems that efficacy of fluconazole in acute cutaneous leishmaniasis is lower than glucantime. A larger clinical trial is recommended. %U https://www.iranjd.ir/article_98544_0d95eb6358e107a2fbfc9e7a993dcb86.pdf