TY - JOUR ID - 132464 TI - Trichilemmal carcinoma in an Iranian patient: reporting a rare skin tumor JO - Iranian Journal of Dermatology JA - IJD LA - en SN - AU - Esmati, Ebrahim AU - Vand Rajabpour, Mojtaba AU - Shirkhoda, Mohammad AU - Soleimani, Vahid AU - Garousi, Maryam AD - Radiation Oncology Research Center (RORC), Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran AD - Radiation Oncology Research Center (RORC), Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran AD - Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran AD - Pathology Department, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran AD - Radiation Oncology Department, Iran University of Medical Sciences, Tehran, Iran Y1 - 2021 PY - 2021 VL - 24 IS - 2 SP - 147 EP - 149 KW - Carcinoma KW - skin KW - Tumor KW - hair follicle KW - Surgery DO - 10.22034/ijd.2020.244451.1196 N2 - Trichilemmal carcinoma is a rare tumor of the outer sheath cells of hair follicles. These tumors occur on the sun-exposed skin of the elderly in the majority of cases. The gross tumor demonstrates exophytic, polypoid, ulcerative, or nodular lesions with or without bleeding. Histopathologically, it is characterized by an anastomosing trabecular, diffuse, or lobular growth pattern with clear keratinization. A critical differential diagnosis is squamous cell carcinoma (SCC), where the prognosis of trichilemmal carcinoma is far better than SCC. Surgery is a significant and effective treatment for trichilemmal carcinoma cases, and recurrence after complete surgical resection with a negative margin is uncommon. Trichilemmal carcinoma is considered a low-grade tumor with low metastatic potential. This paper reports a 48-year-old Iranian male with trichilemmal carcinoma of the scalp treated with surgery, having no recurrence after three years of follow-up. The role of other treatment modalities like radiation, local therapy, and systemic therapy are also discussed. UR - https://www.iranjd.ir/article_132464.html L1 - https://www.iranjd.ir/article_132464_23ce28495ec7854cd451d932d95686fe.pdf ER -