Document Type : Case Report


1 Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia

2 Department of Pathology, Faculty of Medicine and Health Science, Universiti Putra Malaysia, Malaysia


Granuloma annulare (GA) is an idiopathic benign skin disease, characterized by annular dermal plaques or papules. Much is still unknown concerning its aetiology, association, and pathogenesis.
We report two patients with generalized GA (GGA), with different age of presentation, co-morbidities, and disease morphology. Herein, we report two patients with GGA with different clinical features, disease morphologies, and histology patterns. We also illustrate the treatment used in our patients and the outcome. GA is a self-limiting disease and can regress spontaneously. GGA tends to be more persistent and usually requires treatment for symptomatic or cosmetic reasons. Expert consensus on treatments recommends topical corticosteroid, psoralen and ultraviolet A (PUVA), and antimalarial drugs.