Background: Diffuse hair loss is one of the most common complaints of women attending skin clinics. Objective: The purpose of this study was to evaluate diffuse hair loss in women referring to a private office. Patients and Methods: This descriptive, retrospective study was performed on women attending a private skin clinic in Ahwaz complaining of diffuse hair loss. The study was done for 10 months in 1376-77. The patients who were hirsute or had apparent clinical pattern of androgenetic or scarring alopecia were excluded. Results: 68% of the total of 180 patients aged between 10 to 30 years old. Thyroid function disorders was found in 18.8%, and anemia was the only finding in 23% of the patients. Trichotillomania was observed in 3.2% and in 41.4% we could not find any clinical or laboratory positive finding. Conclusion: Women complaining of diffuse hair loss should be screened for thyroid disorders and anemia.