Document Type : Case Report


Department of Family Medicine Universiti Sains Malaysia, Kubang Kerian, Malaysia


Pemphigoid gestationis is an unusual autoimmune dermatosis of pregnancy, and recurrences may occur in consequent pregnancies. This dermatosis begins with intense itching, which progresses to papules and annular plaques and, consequently, vesicles and tense bullae. These lesions typically arise from the umbilical region then spread centrifugally to the abdomen, thighs, palms, and soles. Diagnosis is based on clinical examination and immunohistopathologic studies. Here, we report the case of a 29-year-old women who developed recurrent pemphigoid gestationis in her second pregnancy and the postpartum period in 2020. The condition initially manifested during her first pregnancy in 2014. She was successfully treated with oral prednisolone and the local application of betamethasone cream. Pruritic skin lesions are a common complaint among pregnant women. Clinicians should be aware of autoimmune dermatosis of pregnancy, its fetomaternal and neonatal complications, and its possibility of recurrence in subsequent pregnancies.