Document Type : Original Article
Authors
1 Dermatology Unit, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor, Malaysia
2 Discipline of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor, Malaysia
3 Dermatology Unit, Faculty of Medicine, National University of Malaysia Medical Centre, Kuala Lumpur, Malaysia
Abstract
Background and Aim: Silicone-based products are often used to improve signs and symptoms of hypertrophic and keloid scars. An improved silicone product, ScarLess™ Hydrogel (SH), is a 5% silicone-based super-oxidized hydrogel meant to reduce keloid scars’ vascularity, elasticity, and height. This study aimed to compare the efficacy between SH and hydrocortisone (HCT) 1% ointment in keloid treatment.
Methods: This study was a prospective, single-centered, randomized, double-blind study involving twenty-eight subjects with keloid scars. The scars were assigned randomly as Scar A and Scar B in a 1:1 ratio to receive HCT or SH under occlusion, respectively, for over 12 weeks. The Patient and Observer Scar Assessment Scale (POSAS) was used for clinical evaluation.
Results: According to the POSAS, there were significant improvements in both patient and observer scorings in both treatment arms.
Conclusion: SH has equal therapeutic efficacy as HCT in keloid treatment. SH did not present with any safety issues or side effects.
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