Autoimmune polyendocrine syndromes are a heterogeneousgroup of rare diseases characterized by autoimmune activityagainst more than one endocrine organ, although non-endocrineorgans can also be affected. We report the association of APS Iwith erythema annulare centrifugum in an 18-years-old male whopresented with multiple figurate erythema spreading on his trunkand extremities along with a history of multiple endocrine disorderssuch as diabetes mellitus, hypothyroidism, hypoparathyroidism,hypogonadism, and adrenal insufficiency from one year ago. Toour knowledge this is a very rare association.