Document Type : Case Report



A 30-year-old healthy man came to our hospital with complaints of red, hot, and painful upper extremities which spontaneously appeared. These manifestations worsened with exercises and heat, but were alleviated by rest and cooling of the hands. There were 2 similar previous episodes of short duration. The patient was a healthy, non-alcoholic, non-smoker with no history of using medicine. Routine laboratory tests showed no abnormalities, and he had a normal physical examination. Clinical evolution was uneventful and the skin changes gradually improved after desquamation with complete return to normal features. The clinical features herein described constitute classical characteristics of primary erythromelalgia, an uncommon, possibly underreported condition.