Nassiri Soheila; Saffarian Zahra; Younespour Shima
Volume 16, Issue 1 , 2013, , Pages 1-5
Abstract
Background: Alopecia areata (AA) is an autoimmune disorder ofhair follicles. We aimed to find the association between VitaminD level and AA.Method: Eligible AA patients and controls were enrolled inthis case-control study and serum samples were assessed for25-hydroxy vitamin D (25-(OH)-D3). The levels ...
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Background: Alopecia areata (AA) is an autoimmune disorder ofhair follicles. We aimed to find the association between VitaminD level and AA.Method: Eligible AA patients and controls were enrolled inthis case-control study and serum samples were assessed for25-hydroxy vitamin D (25-(OH)-D3). The levels of 25-(OH)-D3were categorized as deficient (<10ng/ml), insufficient (10 to<30 mg/ml) and sufficient (>30ng/dl) and the SALT (Severityof Alopecia Tool) score was used to assess the severity of thedisease. The data was analysed and the association betweenvitamin D levels and AA, disease distribution, and the patternof hair loss was investigated.Result: Twenty eight patients (19 males, 9 females) and 44healthy controls (16 males, 28 females) were assessed. Therewas no statistically significant difference between patients andcontrols with regard to the level of 25(OH)D3 when the data wasadjusted for gender (Ordinal odds ratio: 0.49 (0.18-1.34 and 95%CI, p-value=0.16). The level of 25(OH)D3 was lower in patientswith nail involvement in contrast to those without it (P=0.02);moreover, no significant difference was found between patientswith different patterns of hair loss.Conclusion: After adjustment for gender, there was no associationbetween AA and the level of vitamin D.
Robati Reza; Ebadi Atyeh; Nazari Sajjad; Saffarian Zahra
Volume 14, Issue 3 , 2011, , Pages 117-118
Abstract
A 33–year-old woman was visited at the dermatological clinic of Loghman-e-Hakim Hospital with multiple hypopigmented patches on her right arm, buttocks and flanks. Her lesions developed over the past year with no regression. Lesions were resistant to multiple antifungal therapies. Clinical examination ...
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A 33–year-old woman was visited at the dermatological clinic of Loghman-e-Hakim Hospital with multiple hypopigmented patches on her right arm, buttocks and flanks. Her lesions developed over the past year with no regression. Lesions were resistant to multiple antifungal therapies. Clinical examination revealed multiple circular or oval patches on the right arm, flank and sacral area. There was no erythema but fine scales were observed on the lesions (Figure1). No cutaneous sensory deficit was detected and no abnormality was found on physical examination. Also, there was no family history of similar problems. Abdominal ultrasonography and chest x-ray were normal. We performed biopsy from one of the lesions.