Sandra Widaty; Eliza Miranda; Sri Linuwih Menaldi; Mufqi Handaru Priyanto; Henin Tirta Kusumawardhani; Aria Kekalih; Kusmarinah Bramono
Abstract
Background: Malassezia folliculitis (MF) is a chronic disease that develops in the pilosebaceous unit, caused by Malassezia species. Patients’ characteristics, clinical manifestations, laboratory examination, and treatment choice affect the clinical recovery in patients with MF. This study aimed ...
Read More
Background: Malassezia folliculitis (MF) is a chronic disease that develops in the pilosebaceous unit, caused by Malassezia species. Patients’ characteristics, clinical manifestations, laboratory examination, and treatment choice affect the clinical recovery in patients with MF. This study aimed to identify several potential factors that determine the treatment outcome of MF.Methods: This retrospective study was conducted at Dr. Cipto Mangunkusumo Hospital, Jakarta, from 2013 to 2017. Eligible patients diagnosed with MF based on clinical and microscopic examinations were included. Clinical outcomes were defined as complete cure or improvement with a decrease in the subjective symptoms (itchiness) and objective symptoms (lesions). Analyses were carried out using STATA version 5.0, and some analyses and graphics were generated in R (version 3.2.2 for Windows), GraphPad Prism version 6.01, and Microsoft Excel.Results: A total of 30 patients with MF were recruited. Several factors had a significant effect on the clinical outcomes such as predilection site (chest; HR 1.422; 95% CI 1.262–1.696; P = 0.018), isolated systemic therapy (HR 1.915, 95% CI 1.441–2.532; P = 0.002), and combination therapy (HR 1.858; 95% CI 1.350–2.541; P = 0.041).Conclusion: Lesions in the chest area, isolated systemic antifungal therapy, and combination therapy were associated with good outcomes following antifungal treatment.
Caroline Oktarina; Danny Surya; Putu Martha Gerynda Sukma; Teguh Hopkop Putera Manurung; Sandra Widaty
Abstract
Background: Scabies is an infestation caused by Sarcoptes scabiei var. hominies, prevalent in children with poor nutritional status and hygiene, particularly in overcrowded communities. Indonesia has 14.5% cases of the double burden of malnutrition among school-aged children. As there has been no study ...
Read More
Background: Scabies is an infestation caused by Sarcoptes scabiei var. hominies, prevalent in children with poor nutritional status and hygiene, particularly in overcrowded communities. Indonesia has 14.5% cases of the double burden of malnutrition among school-aged children. As there has been no study establishing the role of nutritional status in the occurrence of scabies, this study aims to investigate the association between body mass index (BMI) and height with scabies infestation in an Islamic boarding school in Indonesia.Methods: This was a cross-sectional study conducted in an Islamic boarding school in Indonesia with children aged 11-17 years old as participants. Physicians performed anthropometry measurements, and a dermatologist confirmed the diagnosis of scabies through history taking and physical examination. Logistic regression was used to analyze the association between BMI and height and the prevalence of scabies.Results: Of 287 subjects, 135 (47%) were diagnosed with scabies, with a male predominance (66.1%). Most of the subjects had normal weight (76.7%) while 20 (7%) were underweight, and 153 subjects (53.3%) had short stature. Male subjects were four times more likely to be infested by scabies (P < 0.001). Obese and short subjects were 4 and 1.67 times more likely to develop scabies, respectively.Conclusion: Poor nutritional status represented by BMI and height cannot be regarded as an independent risk factor for scabies, while environmental factors might be the most crucial factors in the development of scabies. A holistic approach addressing these factors should be implemented to eradicate scabies in addition to appropriate pharmacological management.
