Behnam Avandi; Mehdi Ghahartars; Navid Moradi Kashkooli; Najmeh Ahramiyanpour; Mohammad Mahdi Parvizi
Abstract
Erythroderma or generalized scaling dermatitis is a condition marked by redness and scaling of more than 90% of the body surface. This study aimed to review the epidemiological and clinical features of erythroderma patients hospitalized in the Dermatology Ward of Shahid Faghihi Hospital, Shiraz, Iran. ...
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Erythroderma or generalized scaling dermatitis is a condition marked by redness and scaling of more than 90% of the body surface. This study aimed to review the epidemiological and clinical features of erythroderma patients hospitalized in the Dermatology Ward of Shahid Faghihi Hospital, Shiraz, Iran. This retrospective cross-sectional was conducted from 2001 to 2017 using patient records. All patients with a diagnosis of erythroderma on record were included in the survey, and those whose data were missing or were not compatible with the clinical diagnosis were excluded. Data were analyzed with SPSS version 22 and Stata version 14.2. Overall, 217 erythroderma patients were admitted to this ward, including 119 (54.8%) men and 98 (45.2%) women. The mean age of the patients was 47.27 ± 19.68 years (range: 4-92 years). Moreover, the most frequent cause of erythroderma was drug reaction (67%); lamotrigine, with a frequency of 12 patients, was the most prevalent prescribed medication in patients with drug reaction-induced erythroderma. The mean duration of hospital stay was 6.64 ± 4.50 days; this parameter was directly associated with the erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) level. Pruritus (41.9%) and fever (15.2%) were the most frequent clinical manifestations among these patients. As erythroderma is a dermatologic condition that medications can induce, patients should be informed about the warning signals and course of the disease before certain medications are prescribed.
Saman Mohammadi; Saeedeh Farajzadeh; Hossein Safizadeh; Maryam Khalili; Mahin Aflatoonian; Rezvan Amiri; Elham Mohammadrezakhani
Abstract
Background: Atopic dermatitis is the most common inflammatory skin disease in children. Severe itching may lead to an impaired quality of life in the patients. In this study, we evaluated the validity and reliability of Persian version of a questionnaire regarding the infants’ ...
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Background: Atopic dermatitis is the most common inflammatory skin disease in children. Severe itching may lead to an impaired quality of life in the patients. In this study, we evaluated the validity and reliability of Persian version of a questionnaire regarding the infants’ dermatitis quality of life in children suffering from atopic dermatitis.Methods: When the original authors approved of the Persian version of the questionnaire, the parents completed the questionnaire for their 98 children with atopic dermatitis aged less than four years. We analyzed the data by SPSS 16. Cronbach’s alpha and inter-item and calculated the correlations to evaluate the reliability and validity via Kaiser criterion and scree plot.Results: The calculated mean score of questionnaire was 9.65±5.41. The first (itching and scratching) and eight questions (treatment problems) obtained the highest and lowest scores, respectively. There was a strong, positive correlation between the severity of the disease and the quality of life score in the patients. Cronbach’s alpha was calculated as 0.88 which is a sign of good internal consistency of the items. The inter-item correlative coefficients varied between -0.004 to 0.87. We used Kaiser’s criterion and scree plot to evaluate the validity and achieve a two-factor solution.Conclusion: Persian version of infants’ dermatitis quality of life index questionnaire was valid and reliable.
Ghanei Nerges; Shafihosseini Mitra; Mohammad Ebrahimzadeh Ardakani; Reza Bidaki
Abstract
Lymphangioma circumscriptum is a rare benign lymphatic malformation, clinically characterized by clusters of translucent vesicles. Uncommon manifestations such as verruciform or zosteriform have also been reported in the literature, yet eczematous-like presentation is extremely rare. The present study ...
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Lymphangioma circumscriptum is a rare benign lymphatic malformation, clinically characterized by clusters of translucent vesicles. Uncommon manifestations such as verruciform or zosteriform have also been reported in the literature, yet eczematous-like presentation is extremely rare. The present study describes the case of a young woman with a 16-year history of an exudative eczematous-like plaque, mistreated as dermatitis which converted to a semi vesicular lesion during the treatment of super infection and was later diagnosed as lymphangioma circumscriptum by histopathology study. It is suggested that since lymphangioma circumscriptum may resemble other diseases such as dermatitis, histology, as the gold standard for diagnosis, should not be forgotten in the clinical context of this entity.
Ghasemibasir Hamidreza; Khezrian Leila; Sobhan Mohammad Reza
Volume 18, Issue 3 , 2015, , Pages 136-139
Abstract
Lichenoid and granulomatous dermatitis is a new entity which is histologically defined by a band like lymphocytic infiltration in the upper portion of the dermis with obscuring the dermoepidermal junction and accompanied by basal layer degeneration and granulomatous inflammation. Herein, we presented ...
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Lichenoid and granulomatous dermatitis is a new entity which is histologically defined by a band like lymphocytic infiltration in the upper portion of the dermis with obscuring the dermoepidermal junction and accompanied by basal layer degeneration and granulomatous inflammation. Herein, we presented two Iranian women with similar cutaneous and histopathologic findings. Both patients had asymptomatic subcutaneous nodules on their hands. The pathological manifestation in both of them was lichenoid and granulomatous dermatitis. Our investigations indicated different underlying causes of the lesions in our patients. In one patient, the lesion was associated with hyperthyroidism and in the other one it was accompanied by rheumatoid arthritis.
Behrooz Barikbin; Afsaneh Maarefat; Rayhaneh Rahgoshai; Hamideh Moravvej; Nahid Mohtasham; Maryam Yousefi
Volume 13, Issue 4 , 2010, , Pages 131-134
Abstract
Background: Hand eczema is one of the most common dermatologic diseases requiring treatment but common therapeutics such as corticosteroids and anti-histamines have numerous side effects. So, use of herbal agents, which generally have no major side effects, may be useful especially if their efficacy ...
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Background: Hand eczema is one of the most common dermatologic diseases requiring treatment but common therapeutics such as corticosteroids and anti-histamines have numerous side effects. So, use of herbal agents, which generally have no major side effects, may be useful especially if their efficacy is established. Malva Sylvestris (MS) is a tropical plant in Iran with cooling characteristics. Hence, in this study, its efficacy in of the treatment of hand eczema was evaluated. Methods: In this randomized clinical trial, 50 patients with hand eczema who were visited at Shohada-e Tajrish and Loghman hospitals, Tehran, Iran, between 2006 and 2008, were recruited and divided into two groups. In the first group, MS 4% ointment was applied twice a day and in the other group, placebo ointment was usd. The efficacy and side effects were evaluated three and six weeks after beginning of the treatment. Results: Mean age of the patients was 37.3 years and 35.6 years in MS and placebo groups, respectively (P > 0.05). There were no therapeutic adverse effects in the groups. There was a statistically significant difference in all measured scores between two groups in the first and second follow-up sessions (P < 0.0001). Conclusion: Malva Sylvestris seems to be a safe and effective therapeutic modality for the treatment of hand eczema and can be used as an optimal substitute for corticosteroids and antihistamines.
Farajzadeh Saideh; Esfandiarpour Iranj; Pourhamzadeh Bahareh
Volume 10, Issue 4 , 2007, , Pages 320-328
Abstract
زمینه و هدف: از آن جایی که بیماری های پوستی در دوران کودکی از جهت های زیادی با افراد بالغ متفاوت است لذا تعیین الگوی شیوع بیماری های کودکان نقش مهمی در تعیین راه کارهای ...
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زمینه و هدف: از آن جایی که بیماری های پوستی در دوران کودکی از جهت های زیادی با افراد بالغ متفاوت است لذا تعیین الگوی شیوع بیماری های کودکان نقش مهمی در تعیین راه کارهای درمانی و پژوهشی دارد. هدف از این مطالعه تعیین الگوی شیوع بیماری های پوستی اطفال در کودکان مراجعه کننده به کلینیک های تخصصی پوست شهر کرمان بود. روش اجرا: در این مطالعه که از نوع توصیفی- تحلیلی، مقطعی است 937 نفر از کودکان زیر 16 سالی که به کلینیک های تخصصی پوست شهر کرمان در فاصله شهریور تا اسفند 85 مراجعه کرده بودند وارد مطالعه شدند. برای هر یک از بیماران پرسش نامه شامل سن، جنس، محل زندگی، تحصیلات والدین و نوع بیماری پوستی تکمیل شد. بیماری های پوستی توسط متخصص و بر اساس علایم و معاینه بالینی و روش های پاراکلینیک شامل بیوپسی، اسمیر و کشت باکتریال، اسمیر قارچ، Woods lamp و Tzank test تشخیص داده شد. یافته ها: طبق نتایج به دست آمده در مجموع درماتیت ها و عفونت های پوستی شایع ترین بیماری ها را تشکیل می داد. در بین درماتیت ها، درماتیت آتوپیک و سبورئیک از بقیه شایع تر و درماتوز پلانتار جوانان و لیکن سیمپلکس مزمن از بقیه نادرتر بود. در بین عفونت ها هم، عفونت های ویروسی و انگلی شایع تر از انواع باکتریایی و قارچی بود. در مقایسه بین دخترها و پسرها خال های ملانوسیتی به طور معنی داری در دخترها بیش تر از پسرها بود (02/0>p). اختلال های کراتینیزاسیون در کودکان مادران تحصیل کرده کم تر مشاهده شد (006/0>p). نتیجه گیری: طبق نتایج به دست آمده، درماتیت آتوپیک شایع ترین بیماری در این مطالعه بود که علت آن ممکن است به دلیل تغییر رژیم غذایی، عوامل پری ناتال و افزایش تماس با آلرژن های محیطی باشد. بیماری شایع بعدی عفونت های پوستی بود که این مطلب نشانه اهمیت توجه به مسایل بهداشتی این گروه سنی است.
Kafaie Parichehr; Soghra Yassaei
Volume 10, Issue 4 , 2007, , Pages 329-112
Abstract
Contact dermatitis can affect dentists, orthodontists, technicians, nurses and the patients. The increase of dental patients in recent years caused an increase in reports of dermatitis and other allergies in patients and in dentists too. With changes in dental materials through years, allergy and contact ...
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Contact dermatitis can affect dentists, orthodontists, technicians, nurses and the patients. The increase of dental patients in recent years caused an increase in reports of dermatitis and other allergies in patients and in dentists too. With changes in dental materials through years, allergy and contact reactions in persons in contact with new allergens had been increased. So dentists and dermatologists should be aware of new allergens and try to avoid contact with these materials as possible. This review is performed to increase the knowledge of medical personnel about this issue with description of each allergen.
Firooz Alireza; Nassiri-Kashani Mansour; Gorouhi Farzam; Davari Parastoo; Yaghoubi Reza; Farshchian Mahmoud; Esfandiarpour Iraj; Golchai Mohammad Javad; Dowlati Yahya
Volume 10, Issue 3 , 2007, , Pages 187-195
Abstract
Background and aim: The frequency of sensitization to contact allergens varies in different countries because of both genetic and, more importantly, allergen exposure variations. The objective is to determine the frequency of sensitization to contact allergens in Iranian patients with dermatitis.Materials ...
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Background and aim: The frequency of sensitization to contact allergens varies in different countries because of both genetic and, more importantly, allergen exposure variations. The objective is to determine the frequency of sensitization to contact allergens in Iranian patients with dermatitis.Materials and methods: Four hundreds and one patients with a clinical diagnosis of contact dermatitis and/or atopic dermatitis were evaluated with a 24-allergen European standard series in four major cities in Iran. The patches were applied on the back of the patients, removed after 24 hours and the readings were taken on 24, 48 and 72 hours after application.Results: One hundred and seventy six patients (43.8%) showed at least 1 positive reaction with a total positive reactions of 268, and 64 patients (15.9%) had 2 or more positive reactions. The 5 most common allergens were nickel sulfate [64 (15.9%)], potassium dichromate [40 (10.0%)], thiuram mix [27 (6.7%)], cobalt chloride [23 (5.7%)], and Balsam of Peru [17 (4.2%)]. Contact allergy to nickel sulfate was significantly more common in female patients and in patients under 40 years of age (P<0.001).Conclusion: Nickel sulfate is the most common contact allergen in Iran, mostly affecting women and younger patients probably because of more exposure. Thiuram had a significant increase in its prevalence during the previous years and further studies need to distinguish its causes.
Alireza Firooz; Mansour Nassiri-Kashani; Reza Sarhangnejad; Mehdi Rashighi-Firoozabadi; Farzam Gorouhi
Volume 10, Issue 1 , 2007, , Pages 26-31
Abstract
Background and aim: Contact dermatitis is an inflammatory skin response due to contact with environmental materials manifested as acute or chronic eczema. Patch test is the standard test to recognize responsible allergen. The objective of this study was to evaluate the frequency of false positive patch ...
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Background and aim: Contact dermatitis is an inflammatory skin response due to contact with environmental materials manifested as acute or chronic eczema. Patch test is the standard test to recognize responsible allergen. The objective of this study was to evaluate the frequency of false positive patch test responses in patients with Exited Skin Syndrome (ESS).Materials and methods: Fourteen patients older than 12 years with allergic contact dermatitis who had more than one positive reaction in first patch test were re-tested with the same allergens at the time of remission of their eczema. The patches were removed after 48 hours and responses read according to ICDRG guidelines.Results: The patients included 5 men and 9 women with a mean age of 34.92 years. The most common allergens in first patch test were: nickel sulfate (10), cobalt chloride (5), colophony (4), potassium dichromate, PTBF, fragrance mix and MCI/MI (3 each). In the repeated test, the most common positive responses were: nickel (10), cobalt and colophony (4 each), potassium dichromate and fragrance mix (3 each). In 6 of 14 patients the results of second test was different from first one. Three of these patients had active eczema at the time of first test, which in 2 of them one positive response and in one of them, 2 positive responses became negative in second test.Conclusion: It is recommended that patch test be repeated after a while in patients with multiple positive reactions in first test, particularly after remission of active eczema.
MA Nilforoush Zadeh; G Sadeghian; F Jafari; AR Firooz; Sh Moradi; R Derakhshan
Volume 9, Issue 1 , 2006, , Pages 35-39
SZ Ghodsi; H Ghani Nezhad; L Farpoor; A Ali Mardani; A Taheri; P Mansoori
Volume 8, Issue 2 , 2005, , Pages 115-120
Abstract
Background: Geographic tongue is an inflammatory disorder of unknown etiology that affects the epithelium of the tongue. It has been associated with several cutaneous diseases. Objective: To determine the prevalence of geographic tongue and its association with other cutaneous diseases in patients referred ...
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Background: Geographic tongue is an inflammatory disorder of unknown etiology that affects the epithelium of the tongue. It has been associated with several cutaneous diseases. Objective: To determine the prevalence of geographic tongue and its association with other cutaneous diseases in patients referred to the dermatology clinic of Razi hospital. Patients and methods: A cross-sectional study was performed on all patients referred to one of the dermatology clinics of Razi hospital between February 21 and March 18, 1996 to determine the prevalence of geographic tongue and other diseases. Results: One-thousand and one-hundred and sixty referred patients were studied. The prevalence of geographic tongue was 6.2%. There was a statistically significant association between geographic tongue and seborrheic dermatitis (P=0.0053). Conclusion: Geographic tongue is associated with some cutaneous diseases. Detection of these associations could be a clue to the etiology and pathogenesis of geographic tongue.