Document Type : Original Article

Authors

• Amirhoushang Ehsani ¹
• Alireza Firooz ^{2, 3}
• Arezou Jam Manesh ⁴
• Amirali Jahanshahi ⁴
• Elnaz Khosravani ⁴
• vahide Lajevardi ^{1, 5}
• Parvin Mansouri ⁶
• Mansour Nassiri Kashani ²
• Reza M Robati ⁷
• Zahra Saffarian ¹

¹ Department of Dermatology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

² Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran

³ Clinical Trial Center, Tehran University of Medical Sciences, Tehran, Iran

⁴ Dr. Abidi Pharmaceutical Company, Tehran, Iran

⁵ Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran

⁶ Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

⁷ Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract

Urticaria is a frequent and difficult-to-treat skin condition, described as temporary erythematous, raised, and itchy skin lesions (wheals) brought on by dilated blood vessels, elevated local blood flow, and increased vascular permeability. It can occur alone or in conjunction with angioedema. Urticaria can be diagnosed and treated in fields other than dermatology; patients often visit general physicians, internal medicine specialists, allergologists, and clinical immunologists. In 2018, the Iranian Society of Dermatology produced a clinical practice guideline on diagnosing and managing urticaria. To update the guideline, the Guideline Development Committee conducted an exhaustive search of scientific papers published on the topic from April 2018 to the end of August 2022, and the new guideline was developed. Finally, the updated guideline was critiqued by members of the Dermatology Board Certificate Examination Panel and chairs of dermatology departments in Iran, and it was improved using their feedback.

Keywords

• urticaria
• diagnosis
• management
• antihistamines
• clinical guideline